Personal Research Database

Title: Journal of Hazardous Substance Research

Full Journal Title: Journal of Hazardous Substance Research

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ISSN: 1344-9702

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? Ray, L., Paul, S., Bera, D. and Chattopadhyay, P. (2005), Bioaccumulation of Pb(II) from aqueous solutions by Bacillus Cereus M¹₁₆. Journal of Hazardous Substance Research, 5 (1), 1-21.

Full Text: 2005\J Haz Sub Res5, 1.pdf

Abstract: Because of the severity of heavy metal contamination and potential adverse health impact on the public, tremendous efforts have been made to purify waters containing toxic metal ions. Biosorption is presented as an alternative to traditional physicochemical means for removing toxic metals from groundwaters and wastewaters. Removal of lead from solution was studied using growing cells and washed cells of Bacillus Cereus M¹₁₆. The removal of Pb(II) ions with growing cells was maximum (85%) when initial lead concentration was 50 mg/L. Other process conditions were optimized. These were volume of medium: 40 ml in a 250-ml Erlenmeyer fl ask, temperature: 30oC, pH: 6.0, fermentation time: 30 hours, and inoculum concentration (24-hour cell growth): 4%. Biosorption of Pb(II) on washed biomass of the selected strain was investigated in batch mode and optimum conditions were determined. The uptake of metal was very fast, and equilibrium was attained within 30 minutes. It was found that the overall adsorption process was best described by pseudo second-order kinetics. Both Langmuir and Freundlich isotherms were tested, and it was found that the latter had a better fi t with the data. The adsorption continuously increased in the pH range of 3.6 – 6.0, beyond which the adsorption could not be carried out due to precipitation of metal. The highest value of lead uptake was 96%, with 1.8 g/L washed biomass (dry basis) at 20C and 92% at 30C.

Keywords: Lead Biosorption, Bacillus sp., Adsorption, Isotherm.

? Ray, L., Paul, S., Bera, D. and Chattopadhyay, P. (2007), Biosorption of chromium(VI) by a mutated strain of Bacillus Cereus M¹₁₆. Journal of Hazardous Substance Research, 7 (1), 1-21.

Full Text: 2007\J Haz Sub Res7, 1.pdf

Abstract: The removal of chromium, a highly toxic metal causing environmental pollution from dilute aqueous solution, was studied in the present work using growing and washed cells of a mutant strain of Bacillus cereus (M¹₁₆) isolated from tannery waste. Particularly, the effects of pH, temperature, metal ion concentration and contact time on removal of chromium were studied. About 40% chromium removal, was observed by growing cells of the selected strain at pH 6.5, temperature 30±1°C, inoculum size 3%, medium volume 50 ml/250 ml Erlenmeyer flask, and initial chromium concentration 50 ppm. Using resting cells 98.02% and 78.34% chromium removal was possible with initial chromium concentration of 25 and 50 ppm, respectively, at pH 3.0, temperature 25-35°C and 2.73 g/L biomass concentration. It was found that the overall adsorption process was best described by pseudo-second order kinetics. Freundlich and Langmuir adsorption models were found suitable for describing the short-term biosorption of chromium(VI). IR spectral analysis of the biomass was carried out to find out the functional groups responsible for chromium(VI) biosorption.

Keywords: Lead Biosorption, Bacillus cereus M¹₁₆, Immobilization, Pseudo Second Order, Freundlich Isotherm

Title: Journal of Headache and Pain

Full Journal Title: Journal of Headache and Pain

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? Schurks, M., Rist, P.M. and Kurth, T. (2010), STin2 VNTR polymorphism in the serotonin transporter gene and migraine: Pooled and meta-analyses. Journal of Headache and Pain, 11 (4), 317-326.

Full Text: 2010\J Hea Pai11, 317.pdf

Abstract: Data on the association between the SLC6A4 STin2 VNTR polymorphism and migraine are conflicting. To perform pooled and meta-analyses, we searched for studies published until September 2009 using electronic databases (MEDLINE, EMBASE, Science Citation Index) and reference lists of studies. Assessment for eligibility and extraction of data was performed by two independent investigators. We extracted allele and genotype frequencies for each study. We then calculated study-specific and pooled odds ratios (OR) and 95% confidence intervals (CI) assuming allele and genotype models. We also calculated pooled ORs and 95% CIs based on study-specific effect estimates for the allele model. We included five studies investigating the association between the STin2 VNTR polymorphism and migraine. Results from the allele model suggested a protective effect against migraine for the STin2.9 and STin2.10 alleles compared to the STin2.12 allele among populations of European descent, which however was not significant. Results from the genotype model indicated a significant similar to 25% reduced risk for migraine among carriers of the 10/12 genotype compared with carriers of the 12/12 genotype among all study populations (OR = 0.76, 95% CI 0.60-0.97) for any migraine, which was more pronounced among populations of European descent (OR = 0.68, 95% CI 0.53-0.87). Results for migraine with and without aura were of similar magnitude, but were not statistically significant. Our results suggest a protective effect of non-STin2.12 alleles compared to STin2.12 alleles, respectively, 10/12 and 10/10 genotypes compared to the 12/12 genotype against migraine among populations of European descent. Associations in non-European populations may differ.

Keywords: 5-HTTLPR Variants, Allele, Association, Aura, Disorders, Headache, Meta-Analysis, Migraine, Population, Regulatory Region, Schizophrenia, Serotonin Transporter, SLC6A4, STIN2 VNTR, Susceptibility