Two Years Eligibility: Bachelor’s degree in Pharmacy with
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- Bu səhifədəki naviqasiya:
- Unit-2 10 hours Entrepreneurship and business development
- Good Laboratory Practices
- Suggested Readings: Gupta, S. (2005). Research methodology and statistical techniques , Deep Deep Publications (p) Ltd.
- Course Tile: Biostatistics L T
- Unit 1 10 hours Overview of biostatistics
- Unit 2 5 hours Experimental design and analysis
- Unit 4 9 hours Regression and correlation
- Course Tile: Biostatistics-Practical L T
- Course Tile: Mid-Term Evaluation of Thesis L T
- Course Tile: Medicinal Chemistry of Anticancer Agents L T
- Unit 1 Introduction
- Unit 2 DNA Alkylating Agents
- Unit 3 Anticancer drugs targeting tubulin and microtubles
- Unit 4 Anticancer drugs targeting receptor and cellular tyrosine kinases
- Course Tile: Thesis Evaluation and Viva Voce L T
Unit 1 10 hours General principles of research: Meaning and importance of research, Critical thinking, Formulating hypothesis and development of research plan, Review of literature, Interpretation of results and discussion. Technical writing: Scientific writing, Writing research paper, Poster preparation and Presentation and Dissertation. Library: Classification systems, e-Library, Reference management, Web-based literature search engines Unit-2 10 hours Entrepreneurship and business development: Importance of entrepreneurship and its relevance in career growth, Characteristics of entrepreneurs, Developing entrepreneurial competencies, Types of enterprises and ownership (large, medium SSI, tiny and cottage industries, limited, public limited, private limited, partnership, sole proprietorship), Employment, self employment and entrepreneurship, Financial management-importance and techniques, Financial statements- importance and its interpretation, Good Laboratory Practices: Recent updates on good laboratory practices. Unit-3 16 hours Intellectual Property Rights: Intellectual Property, intellectual property protection (IPP) and intellectual property rights (IPR), WTO (World Trade Organization), WIPO (World Intellectual Property Organization), GATT (General Agreement on Tariff and Trade), TRIPs (Trade Related Intellectual Property Rights), TRIMS (Trade Related Investment Measures) and GATS (General Agreement on Trades in Services), Nuts and Bolts of Patenting, Technology Development/Transfer Commercialization Related Aspects, Ethics and Values in IP. Suggested Readings:
Unit 1 10 hours Overview of biostatistics: Difference between parametric and non-parametric statistics, Univariant and multivariant analysis, Confidence interval, Errors, Levels of significance, Hypothesis testing. Descriptive statistics: Measures of central tendency and dispersal, Histograms, Probability distributions (Binomial, Poisson and Normal), Sampling distribution, Kurtosis and Skewness. Unit 2 5 hours Experimental design and analysis: Sampling techniques, Sampling theory, Various steps in sampling, collection of data-types and methods. Unit 3 12 hours Comparing means of two or more groups: Student’s t-test, Paired t-test, Mann-Whitney U-test, Wilcoxon signed-rank, One-way and two-way analysis of variance (ANOVA), Critical difference (CD), Least Significant Difference (LSD), Kruskal–Wallis one-way ANOVA by ranks, Friedman two-way ANOVA by ranks, χ2 test. Unit 4 9 hours Regression and correlation: Standard errors of regression coefficients, Comparing two regression lines, Pearson Product-Moment Correlation Coefficient, Spearman Rank Correlation Coefficient, Power and sampling size in correlation and regression. Suggested Readings:
Performing statistics analyses using MS Excel Analysis toolpack and other softwares with respect to the topics mentioned in theory Suggested Readings:
Semester 4
Unit 1 Introduction: Cancer chemotherapy, role of chemistry in cancer chemotherapy, natural products in cancer chemotherapy; Antimetabolites: Introduction, inhibitors of biosynthesis of uridylic acid, 2’-Deoxyribonnucleotides, Thymidilic acid, Dihydrofolate reductase (DHFR), Inhibitors of the De Novo Purin Biosynthesis pathway, Inhibitors of Adenosine Deaminase, Antimetabolite Enzymes. Anticancer drugs that inhibit hormone action: Introduction, Estrogens and their involvement in Carcinogenesis, Antiestrogens as antitumor drugs, Aromatase inhibitors; Steriod sulfatase inhibitors; Androgen-Related Antitumor Agents; Micellaneous Steriodal Harmone-Related Anticancer Therapy. Unit 2 DNA Alkylating Agents: Introduction, Nitrogen Mustards, Aziridines, Epoxides, Methansulfonates, Nitrosoureas, Triazenes, Methylhydrazines, 1,3,5-Triazines, Miscellaneous alkylating and acylating agents antitumor Agents. Alkylating and Non-Alkylating compounds interacting with the DNA Groove: Introduction, Netrospin, Distamycin and related compounds, Mitomycins, Tetrahydroisoquinlinne alkaloids, cyclopropylindole alkylating agents, Pyrrolo[1,4]Benzodiazepines. Unit 3 Anticancer drugs targeting tubulin and microtubles: Introduction, Drugs that inhibit microtubule polymerization binding at the taxane site, Miscellaneous Anticancer drugs acting on novel sites on Tubulin. Anticancer drugs acting via radical species, photosenitizers and photodyanimic therapy cancer, Antithracyclines and their analogs, Mitoxantrone and related quinines, Actinomycin D; Chartreusin, Elsamicines A and related compounds, Bleomycins, Enediyne Antibiotics, Tirapazamine, Penclomedine. Unit 4 Anticancer drugs targeting receptor and cellular tyrosine kinases: Other approach to targeted Therapy; proteasome Inhibitors, Epigenetic therapy etc. Suggested Readings:
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