Name: Manuel F. Casanova


Citations in popular media



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Citations in popular media


  • Magnetic promise: Can brain stimulation treat autism? By Lydia Denworth. Spectrum News, September 23, 2015. http://spectrumnews.org/features/deep-dive/magnetic-promise-can-brain-stimulation-treat-autism-2/




  • Brain stimulation holds promise in autism treatment by Lydia Denworth, Newsweek, September 2015. http://europe.newsweek.com/brain-stimulation-holds-promise-autism-treatment-333346




  • Brain organoids provide insight into autism. http://bit.ly/1I8X4tT July 17, 2015.

  • Ultrasound and autism. http://fearlessparent.org/ultrasound-and-autism/ 2014 January 27.




  • Kelly Brogan [interviewer]. Ultrasounds—safe and sound? [radio program]. Fearless parent radio, 2013 December 18.




  • Jenni Laidman. Trouble in mind. Louisville magazine 2013 August; 64(8): 56–62.




  • Alan Alda [moderator]. Alan Alda talks with the experts: discussions on dyslexia. The Kildonan School, 2013.




  • Jennifer Margulis. Are ultrasounds causing autism in unborn babies? Women in the world. 2013 April 29.




  • Jennifer Margulis. Ultrasound exposure and autism: Dr. Manuel F. Casanova, M.D., cautions against the overuse of ultrasounds. 2013 April 8.




  • Virginia Hughes. Autism brains marked by weak local connections, study says. 2013 February 21.




  • Karen Weintraub. Freezer meltdown could seriously impede autism research The Boston globe 2012 December 3.
  • Jennifer Margulis. The business of baby: what doctors don’t tell you, what corporations try to sell you, and how to put your pregnancy, childbirth, and baby before their bottom line. New York: Scribner, 2013 April 16.

  • Karen Weintraub. Autism: banking on new brain donors. BBC future 2012 August 22.

  • Migdalia Fernández. Intensa la polémica sobre el autismo. LaPrensa 2012 August 16.

  • Rachel Gotbaum. Freezer meltdown could seriously impede autism research [radio program]. First broadcast Monday, 2012 June 11 on WBUR, Boston.

  • John Elder Robison Ultrasound and autism—a connection? My life with Asperger’s: How to live a high-functioning life with Asperger’s [weblog]. 2012 May 21.

  • John Elder Robison. Ultrasound and autism—a possible link? Look me in the eye [weblog]. 2012 May 20. Emily Williams and I have elaborated on the topic in a May 28 post, More thoughts on ultrasound, questions about risk, and autism.

  • John Cacioppo and Laura Freberg. Discovering psychology: the science of mind. Florence, Kentucky: Wadsworth; 2012 March 16 (in press).

  • C. L. Haines and Sally J. Colletti (editors). Autism and seizures: a hidden connection? London: Jessica Kingsley; 2012.

  • Elizabeth Woosley (WDRB.com). Doctor raises autism concerns about ultrasounds. http://www.wdrb.com/story/16103395/doctor-raises-autism-concerns-about-ultrasounds. November 22, 2011.

  • Virginia Hughes. Autism brains have too many neurons, study suggests. SFARI Autism research Inititative, November 10, 2011 http://sfari.org/news-and-opinion/news/2011/autism-brains-have-too-many-neurons-study-suggests

  • John Cacioppo and Laura Freberg, Discovering Psychology: The Science of Mind, Cenage Learning, 2012 (in press).

  • Danielle Venton: The Unappreciated Benefits of Dyslexia. Wired, September 20, 2011 http://www.wired.com/wiredscience/2011/09/dyslexic-advantage/

  • Lida Geddes: Empathy enhanced by magnetic stimulation of the brain. The New Scientist, magazine issue 2827, August 24, 2011.


  • Brock L. Eide and Fernette Eide: The dyslexic advantage. New York: Penguin; 2011.

  • C. Lisa Haines and Sally Thorpe Colletti (editors): Autism and seizures: the hidden connection. London: Jessica Kingsley; 2010.

  • Gregg Miller: New clues about what makes the human brain special. Science 330: 1167, 2010.

  • Sara Lee Kessler: Decoding autism [television program]. First broadcast Monday, 2010 September 27 at 9:00 p.m. on NJN1. (Preview on Youtube http://www.youtube.com/watch?v=a97i7Dl47vI)

  • Daniel Bennett: How to spot a genius. BBC focus 2010 September; 220: 38–43.

  • Melissa Swann: U of L scientists: Promising results in autism treatment [television program]. WHAS11 News @ 11pm. First broadcast Monday, 2010 July 26 at 11:00 p.m. on WHAS11.

  • Melissa Swann: Could autism be linked to ultrasounds? U of L doctor speaks out [television program]. WHAS11 News at 6pm. First broadcast Monday, 2010 July 26 at 6:00 p.m. on WHAS11.

  • Rob Sidell: Dr. Manuel Casanova [radio program]. Weekend autism global news in review. First broadcast Saturday, 2010 July 24 on AutismOne Radio.

  • Adam Feinstein: A history of autism: Conversations with the pioneers. Chichester: Wiley-Blackwell; 2010 July 20.

  • Olga Bogdashina: Autism and the edges of the known world: Sensitivities, language and constructed reality. London: Jessica Kingsley; 2010 July 10.

  • Gina Shaw: In another federal decision, court rules no autism-vaccine connection. Neurology Today Breaking news blog, 2010 May 11.

  • Darold Treffert: Islands of genius: The bountiful mind of the autistic, acquired, and sudden savant. London: Jessica Kingsley; 2010 April 15.

  • TMS in clinical trials as treatment for autism. OPEN MINDS On-line News, 2010 March 29. [local copy]

  • Marcus du Sautoy (presenter): What makes a genius? [television program]. Horizon, series 2009–2010, episode #13. First broadcast Wednesday, 2010 February 17 at 21:00 on BBC Two.

  • Dr. Manuel Casanova & University of Louisville autism research [television program]. Louisville Life, episode #408. First broadcast Thursday, 2009 November 19 at 7:30 p.m. on KET2.

  • Laura Ungar: Rising autism rate no surprise to experts, parents. Louisville courier-journal, 2009 October 5.

  • John R. Anderson: Cognitive psychology and its implications. New York: Worth; 2009 October 1.

  • Virginia Gewin: Studies of brain structure boost ‘connectivity theory’ of autism. News & commentary (New York: Simons Foundation), 2009 July 21.

  • Kelly House: UL researcher may have found link between conditions such as autism, dyslexia. Louisville courier-journal, 2009 July 21.

  • Laura Ungar: U of L researcher receives autism grant. Louisville courier-journal, 2009 June 22.

  • Lori Lyle: UofL autism study gets additional funding. WAVE-TV, 2009 June 22.

  • Carolyn Y. Johnson: Magnetic field tests “reflexes” of autism. Boston globe, 2009 June 8.

  • Thomas R. Collins: First pure autism mouse model created. Neurology Today 2008 November 20; 8(22): 1,9–10.




  • Helen Phillips: The outer limits of the human brain. The new Scientist. Magazine issue 2676, October 1, 2008.




  • Maia Szalavitz. Do supercharged brains give rise to autism? The New Scientist. Magazine issue 2674, September 19, 2008.

  • Temple Grandin: The way I see it: a personal look at autism and Asperger’s. Arlington: Future Horizons, 2008 September 1

  • Michael S. Gazzaniga: Human: the science behind what makes us unique. New York: Ecco, 2008 June 24.

  • T. O. Daria: Dasha’s journal: a cat reflects on life, catness and autism. London: Jessica Kingsley, 2008 April 30.

  • Tom Paulson: “Love hormone” may emerge as a treatment for autism. Seattle post-intelligencer, 2007 May 4.

  • Keith Seinfeld: Autism and brain development [radio program]. KPLU, Seattle, 2007 May 4.

  • Michael Balter: Brain evolution studies go micro. Science 2007 March 2; 315: 1208–1211.

  • Ingrid Wickelgren: Autistic brains out of synch? Science 2005 June 24; 308, 1856–1858.

  • Dana Alliance for Brain Initiatives. 2005 progress report on brain research: Arts and cognition. New York: Dana Press, 2005.

  • Kendall Powell: Opening a window to the autistic brain. PLoS biology 2004 August 17; 2(8): 1054–1058.

  • Erica Goode: Lifting the veils of autism, one by one. New York times, 2004 February 24.

  • Kurt Samson: New studies shed light on brain changes in early autism. Neurology Today 2002 August; 2(8): 1,18–19.

INVITED LECTURES AND SEMINARS


"Cortex", Neuropathology Neuroanatomy Lecture Series, The Johns Hopkins University School of Medicine, Baltimore, Maryland, July, 1985.

"Current Concepts on Alzheimer's Disease", National Institute of Mental Health, Washington, D.C., March 24, 1986.

"Genetic Linkage Studies in Huntington's Disease and Related Conditions", Huntington's Disease Foundation of America, Inc, Washington, D.C., April 17, 1986.

"Alzheimer's Disease: Recent Neuropathological Findings", George

Washington University, Washington, D.C., October, 1986.

"The Neuropathology of Schizophrenia", National Alliance for the Mentally Ill, Washington, D.C., September, 1987.

"Neuropathological Studies on the Limbic System of Schizophrenic Patients", American College of Neuropharmacology, Puerto Rico, December, 1988.

"Where is the Pathology in Schizophrenic Brains?" International Congress of Schizophrenia Research, California, April, 1989.

"The Brain in Schizophrenia", The National Alliance for the Mentally Ill, "Research Symposium: State of the Brain", Illinois, April 7, 1989.

"Magnetic Resonance Imaging in Rett Syndrome", Rett Syndrome Research Symposium, the Kennedy Institute, Baltimore, May 19, 1989.

"The Neuropathology of Schizophrenia: Old Findings and New Ideas", Maryland Psychiatric Institute, Catonsville, Maryland, November 13, 1989.

"Neuroimaging Studies in Schizophrenia", Child Psychiatry Branch Seminar, NIH, Bethesda, November 28, 1989.

"Issues in Brain Banking as Related to Schizophrenia Research", Grand Rounds in Internal Medicine (Neurology), University District Hospital, Hato Rey, Puerto Rico, December 12, 1989.

"The Neuropathology of Schizophrenia", Grand Rounds in Psychiatry, Pilgrim Psychiatric Center, New York, May 9, 1990.

"Recent Advances in Neurobiologic Research in Schizophrenia", The John H. Kending Neuroscience Lecture, St. John's Mercy Medical Center, July 18, 1990.

"The Neuropathology of Schizophrenia", Grand Rounds in Psychiatry, Howard University, Washington, D.C., August 14, 1990.

"Postmortem Neuropsychiatry Studies: Methodological Issues", American College of Neuropsychopharmacology, December 10-14, 1990.

"The Neuropathology of Schizophrenia: Developmental vs Neurodegenerative Etiology", American College of Neuropsychopharmacology, December 10-14, 1990.

"The Neuropathology of Schizophrenia Revisited", Medical College of Georgia, March 7-8, 1991.

"Entorhinal Cortex Pathology in Schizophrenia", American Psychiatry Association Annual Meeting, New Orleans, May 11-16, 1991.

"Neuroanatomical and Neurochemical Pathology in Schizophrenia", Review of Psychiatry (vol 10) session, American Psychiatry Association Annual Meeting, New Orleans, May 11-16, 1991.

"NIMH Postmortem Brain Studies in Schizophrenia", 5th World Congress on Biological Psychiatry, Florence, Italy, June 9-15, 1991.

"Recent MRI Findings on Corpus Callosum Morphometry in Schizophrenia", 5th World Congress on Biological Psychiatry, Florence, Italy, June 9-15, 1991.

"The Neuropathology of Schizophrenia", sponsored by the New York Medical College, Department of Psychiatry and Behavioral Sciences, Valhalla, New York, and the Medical Examiners Office of Westchester County, July 29, 1991.

"Postmortem Findings in a Case of Childhood Schizophrenia", Early-Onset Schizophrenia Workshop, Rockville, Maryland, September 23, 24, 1991

"The Neuropathology of Schizophrenia", Grand Rounds in Psychiatry, The Johns Hopkins Hospital, Baltimore, Maryland, September 30, 1991.

"Neuroimaging and Neuropathology in Psychiatry Research", Grand Rounds in Psychiatry, Eisenhower Hospital, Ft. Gordon, Georgia, November 27, 1991.

"The Organic Substratum of Schizophrenia", Augusta/North Augusta

Regional School of Medicine Alumni Dinner, Augusta, Georgia,

January 23, 1992.

"Borderlands Between Psychiatry and Neurology: The Neuropathology of Schizophrenia", Grand Rounds in Neurology, Medical College of Georgia, February 20, 1992.

"The Role of Thiamine in Psychiatry", Grand Rounds in Child Psychiatry, Child Psychiatry Branch, Bethesda, Maryland, March 2, 1992.

"The Neurobiology of Childhood Onset Schizophrenia", American College of Neuropharmacology Annual Meeting, San Juan, Puerto Rico, December, 1992.

"The Role of Brain Banking in Neuropsychiatry Research", The Augusta Alliance for the Mentally Ill, May 14, 1992.


“Alzheimer's disease: recent advances and historical disappointments”, Grand Rounds in Psychiatry, Medical College of Georgia, August 20, 1992.
"Recent Advances in Neuroimaging", Invited lecture for Proyecto de

Autismo Infantil, Recinto de Ciencias Medicas, Rio Piedras, Puerto



Rico, August 10, 1992.
"Schizophrenia in Layman's Terms", Invited lecturer for the Aiken chapter of the NAMI organization, October 27, 1992.
"Recent Neuropathological Studies in Schizophrenia: Their Relevance to our Understanding of the Disease", Grand Rounds in Psychiatry, Central State Hospital, Milledgeville, Georgia, November 23, 1992.
“Erythrocyte Transketolase Abnormalities in Childhood Schizophrenia”, American College of Neuropharmacology, San Juan, Puerto Rico, December 14-18, 1992.
"Morphological Variability in the Brains of Normal Monozygotic Twins", Dean’s Symposium: Research Progress Report, The Medical College of Georgia, March 23, 1993.
"Recent Advances in Alzheimer's Disease", Alzheimer's Association Annual Conference for Caregivers, Black Mountain, North Carolina, November 5, 1993.
"Organ and Tissue Procurement" Symposia given at the Alzheimer's Association Annual Conference for Caregivers, Black Mountain, North Carolina, November 5, 1993.
“Alzheimer’s Disease: A Historical Perspective”, Institute of Molecular Medicine and Genetics, Medical College of Georgia, January 25, 1996.
“Dementia: An Old Wine in a New Bottle”, Grand Round, Department of Pathology, Medical College of Georgia, February 2, 1996.
“Alopecia Areata”, Department of Dermatology, Medical College of Georgia, February 15, 1996.
"A Biopsychosocial Model for Behavioral Interventions in Medical Illnessess", Grand Rounds in Psychiatry, Medical College of Georgia, April 17, 1997.
"Therapeutic Interventions in Alzheimer's Disease" 5th Annual Alzheimer's Symposium at the Capital Senior Center in Columbia, South Carolina, 1997.
“Recent Histological and Imaging Findings in Schizophrenia: Clues to Etiology”, Grand Rounds in Psychiatry, Medical College of Georgia, January 29, 1998.
“Degenerative Changes in Schizophrenia”, World Psychiatry Association, Symposium on the Neurobiology of Schizophrenia. Guadalajara, Mexico, October 28 to 31, 1998.
“Minicolumnar Pathology in Schizophrenia”. World Congress of Pathology, Satellite Symposium on the Neuropathology of Schizophrenia, Oxford, England, September 8, 2000.
“From Quandry to Quagmire: Asperger’s Syndrome”, Grand Rounds in Psychiatry, Medical College of Georgia, September 21, 2000.
“The Neuropathology of Certain Psychiatric Conditions: Schizophrenia and Autism”, Grand Rounds in Psychiatry, University of Alabama at Birmingham, October 10, 2000.
“Limbic Tauopathy in Late-Onset Schizophrenia”, Grand Rounds in Psychiatry, Medical College of Georgia, October 26, 2000.
“Brain circuitry: Evolution and Pathology”, MF Casanova and D Buxhoeveden, Colloquium Series in Psychology, University of South Carolina, February 27, 2001.
“Minicolumnopathies: Autism and other Disorders of Brain Circuitry”, Grand Rounds, Department of Neurology, Medical College of Georgia, March 28, 2002.
“Psychiatry and Neurology: Disorders of Circuitry vs. Single Cell Pathology”, Grand Rounds, Department of Psychiatry, Medical College of Georgia, April 25, 2002.
“Disorders of Brain Circuitry”, Homecoming and Presidential Inauguration, Medical College of Georgia, April 26, 2002.
“Minicolumnopathies: Autism and other Disorders of Brain Circuitry”, Research Symposium, Department of Psychiatry, McMaster University, Hamilton, Canada, May 1, 2002.
“Neocortical Circuitry and Psychiatry”, Invited Lecturer, Department of Psychiatry, Oxford University, England, October 29, 2002.
“Minicolumnar Pathology in Psychiatry and Neurology”, joint lecture for the Department of Psychiatry and Department of Integrative and Molecular Neuroscience, Imperial College, London, England, October 30, 2002.
“Cortical Minicolumns”, Cliniconeuropathology Reports and Panel, International Meeting for Autism Research, Orlando, Florida, November 2, 2002.
“Astrocytosis in Schizophrenia”, Stanley Medical Research Institute’s Glia Symposium, Bethesda, Maryland, November 12, 2002.
“Minicolumns and minicolumnopathies: Relevance to autism”, Neurosciences Center, University of California at Davis, Davis, California, March 25, 2003.
“Minicolumns and minicolumnopathies: Relevance to autism”, MIND Institute, University of California at Davis, Sacramento, California, March 26, 2003.
“Autism as a minicolumnopathy”, Minisymposium of Neuroanatomy in Autism, Autism Tissue Program meeting at New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York, April 25, 2003.
“Intracortical Circuitry: One of Psychiatry’s Missing Assumptions”, Neuroscience Grand Rounds, Medical University of South Carolina, Charleston, SC, August 28, 2003.
“Morphological and Clinical Characteristics of Minicolumnopathies: Disturbances of Language and Cerebral Dominance,” American College of Neuropharmacology, San Juan Puerto Rico, December 9, 2003.
“The Modular Organization of the Neocortex: The Future Beyond the Neuronal Doctrine”, Anatomy Grand Rounds, University of Louisville, Louisville, Kentucky, January, 2004.
“Neocortical Pathology in Psychiatric Conditions”, Psychiatry Grand Rounds, University of Louisville, Louisville, Kentucky, February 26, 2004.
“Cortical Circuitry in Psychiatric Conditions”, Psychiatry Grand Rounds, University of Cincinnati Medical Center, September 15, 2004.
“Cortical Circuitry in Psychiatric Conditions,” Psychiatry Grand Rounds, University of Kentucky, Lexington, Kentucky, September 22, 2004.
“Minicolumns and Neuropathology,” Department of Pathology and Laboratory Medicine, Research Conference Series, University of Louisville, October 28, 2004.
“Neocortical Minicolumns,” Integrating the Clinical and Basic Sciences of Autism: a Developmental Biology Workshop, Ft. Lauderdale, Fl., Nov 12-14, 2004.
“Recent Developments in the Neuropathology of Psychiatric Illnesses,” Psychiatry Grand Rounds, University of Louisville, Louisville, Kentucky, February 24, 2005.
“Cortical Structure”, EURON Course “Stereology for Neuroscience Research”, in Maastricht, The Netherlands, May 29, 2005.
“Anomalias en Circuitos Corticales (Minicolumnas) en Cerebros de Pacientes Autistas." IV Simposium Internacional Sobre Autismo auspiciado por La Asociación de Padres de Niños Autistas (APNA), Madrid, Espana (Spain), May 4-6, 2005.
“Laws of Conservation in Brain Growth and Evolution.” Annual Neuroscience Day. Society for Neuroscience, the Louisville Chapter, April 21, 2005.
“Minicolumnar Variability across Species,” Yerkes National Primate Center, Atlanta, May 18, 2005.
“Cell Arrays (Minicolumns) in Normal Development and Pathology,” Embryology, Imaging, and Education, American Association of Anatomists, Bethesda, Maryland, July 15-16, 2005
“Cortical Circuitry in Autism,” Grand Rounds in Child Psychiatry, University of Lousiville, Louisville, KY, October 5, 2005.
“Cortical Circuitry in Autism,” Psychiatry Grand Rounds, Medical University of South Carolina, Charlestone, SC, October 14, 2005.
“Abnormalities of Cortical Modular Organization in Autism,” Association for Research in Nervous and Mental Disease and the New York Academy of Medicine, New York, December 2, 2005.
“Minicolumnar Organization of the Neocortex: Implications for Autism Research,” Child Study Center and section of Neurobiology, Yale University School of Medicine, December 9, 2005.
“Cortical Modularity: Normal Physiology and Pathological Aspects,” Birth Defect Center Research Seminar, University of Louisville, February 14, 2006.
“Cortical Abnormalities in the Modular Arrangement of the Cortex in the Brains of Autistic Patients,” Institute for Psychiatric Research Grand Rounds, Indiana University School of Medicine, Indianapolis, Indiana, February 16, 2006.
“The Neurobiology of Autism”, Dutch National Autism Congress, Netherlands, March 17, 2006.
“Cortical Modularity,” The Birth Defects Center Seminar Series, University Of Louisville, March 21, 2006
“Cortical modularity in the normal and Pathological State,” The Cajal Centenary Conference on the Cerebral Cortex, Barcelona, Spain, April 25, 2006.
“Abnormalities of Cortical Circuitry in the Brains of Autistic Individuals,” Autism One Congress, Chicago, Ill May 26-27, 2006.
“Abnormalities of Cortical Circuitry in the Brains of Autistic Individuals,” Grand Rounds, Department of Psychiatry, University of Louisville, June 8, 2006.
“The Cortical Organization of the Brain,” Biology Honors Seminar, Belknap Campus, University of Louisville, March 9, 2007.
“The Anatomy, Ontogenesis and Pathology of the Minicolumn with a Special Emphasis on Autism,” Institute of Brain Research, Staten Island, New York, March 16, 2007
“The Brain of Autistic Patients: What is Wrong and How can We Improve It,” Autism Awareness Festival, Home of the Innocents, Louisville, KY, April 14, 2007.
“Minicolumnopatias,” II Conferencia Internacional Autismo Mas CasadeVall, Barcelona, Spain, April 20-21, 2007.
“What is Wrong with the Brains of Patients with Autism and How can We Fix It?” Autism One, May 24, 2007.
“Autism Research: From Benchtop to Bedside”, School of Public Health, University of Louisville, June 27, 2007.
“Biological Underpinnings of Autism,” Centenary Celebration of Saint-Justine Hospital, Montreal, Quebec, Canada, October 24, 2007.
“The Neurobiology of Autism,” Food and Drug Administration Center for Drug Evaluation and Research (CDER), Visiting Professor Lecture Series (VPLS) cosponsored by the Division of Psychiatry Products and the Office of Training and Communications (OTCOM), Washington, DC, September 10, 2007.
“TMS and Autism” in “Strategies for Developing Novel Interventions for Neurodevelopmental Disorders: An NIMH Workshop” October 2007.
“Cortical Modularity and Autism”, First Cortical Modularity and Autism Congress, Autism Speaks (sponsor), University of Louisville, Louisville, October 12-14, 2007.
“Cortical Modularity and Autism”, Psychology and Brain Colloquium Series, Department of Psychology, University of Louisville, October 15, 2007.
“Systems Theory and Brain Organization”, Governance and Leadership: Chaos Perspective (Course by Drs. James Taylor and John Morse), University of Louisville, February 28, 2008.
“Laws of Conservation as Applied to Brain Growth and Pathology”, The Mathematical Biology Seminar, University of Louisville, March 7, 2008.
“Neuropatologia del autismo”, Curso de actualizacion en el diagnostico del autismo, El Concejo nacional de rehabilitacion y Educacion Especial, La Valencia de Heredia, Costa Rica, August 23, 2008.
“Neuroanatomia de la corteza cortical”, Curso de actualizacion en el diagnostico del autismo, El Concejo nacional de rehabilitacion y Educacion Especial, La Valencia de Heredia, Costa Rica, August 23, 2008.
Nuevos hallazgos en la neurobiologia del autismo”, Curso de actualizacion en el diagnostico del autismo, El Concejo nacional de rehabilitacion y Educacion Especial, La Valencia de Heredia, Costa Rica, August 23, 2008.
Cortical Connectivity and Talent in Autism. Royal Society of Medicine, London, England, September 29, 2008.
The Long and the Short of It: Relating Radial Cytoarchitecture to Patterns of Cortical Connectivity in Autism. Grand Rounds, Child Study Center, Yale University School of Medicine, October 21, 2008.
Autism: From Benchtop to Bedside. Honors Biology Seminar. University of Louisville, November 5, 2008.
“A General Introduction to Minicolumnopathies,” Distinguished Lecture Series, University of Pennsylvania, January 15, 2009.
“The Role of Minicolumns in Alzheimer’s Disease”, HSC Research Networking Forum: Alzheimer’s disease, University of Louisville, March 18, 2009.
“Cortical Hyperexcitability and Seizures in Autism”, Elias Tembenis Seizures Presentation Series, Autism One, Chicago, May 23, 2009.
“Sensory Problems in Autism: Origins and Possible Intervention”, Autism One, Chicago, May 24, 2009.
“Autism research: An Update”, Oakwood Community Center, Somerset, Kentucky, May 26, 2009.
“Cortical Modularity and Autism”, Research Symposium, Brain Institute, University of Utah, Salt lake City, UT, August, 28, 2009.
“Research in Psychiatry”, Honors Biology Lecture Series, University of Louisville, Louisville, KY, September 23, 2009.
“Autism: An Update”, Convencion Annual del Colegio de Medicina, Universidad de Puerto Rico, October 10, 2009.
“Sensory Integration Problems in Autism”, Autism Update, Jewish Hospital, Louisville, KY, October 30, 2009.
“Transcranial Magnetic Stimulation Study of Gamma Frequency Induction in Response to Illusory Figures in Patients with Autism Spectrum Disorders”. Panel Presentation. International Society for Neurofeedback & Research, Annual Conference, Indianapolis, Indiana, September 4, 2009.
“A Case of an Elderly Woman with Delusions Progressing into Dementia”, Cognitive Case Conference, Jewish Hospital, Louisville, KY, November 2, 2009.
“The Neurobiology of Autism”, Third Annual Autism Summit. Southern Indiana Autism Resource Center, Sheraton, Jeffersonville, November 20, 2009.
Minicolumnopathies in Mental Disorders. In Modularity of Mental Disorders Symposium. DGPPN Congress 2009, Berlin, Germany, November 25-29, 2009.
“Autism: Neuropathology, Treatment and Risk Factors”, OB-GYN Grand Rounds, University of Louisville, February 9, 2010.
“Postmortem Studies in Autism”, Special Interest Group (SIG) on Postmortem Studies, International Meeting for Autism Research, Philadelphia, Pennsylvania, May 20, 2010.
“Autism and Ultrasound”, Special Interest Group (SIG) on Maternal Influences in Autism, International Meeting for Autism Research, Philadelphia Pennsylvania, May 22, 2010.
“The Potential Effects of Ultrasound on Fetal Development: Significance for Autism”, Autism One, Chicago, Il., May 29, 2010
“The Neurobiology of Autism: The Role of Ultrasound”, Autism One, Chicago, Il., May 30, 2010.
“The Role of the Cortex and the Genesis of Seizures in Autism,” Autism One, Chicago, Il., May 30, 2010.
“The Neurobiology of Autism: An Update”, Grand Rounds Child Psychiatry Division, Department of Psychiatry, University of Louisville, October 6, 2010.
“Translational Research in Autism: From Postmortem Studies to Clinical trials”, Greenwood Genetics Center, Greenwood, South Carolina, October 14, 2010.
“Autism Research: From Benchtop to Bedside”, Grand Rounds in Pediatrics, Greenville Hospital System, University Medical Center, Greenville, South Carolina, October 15, 2010.
“Macroscopic Correlates to the Minicolumnopathy of Autism: Implications for Corticocortical Connectivity. American Academy of Child and Adolescent Psychiatry, 57th Annual Meeting, New York, New York, October 26, 2010.
“Autism: An Overview”, Keynote lecture, Autism Spectrum Academy, Salt Lake City, Utah, November 12, 2010.
“La Neurobiologia del Autismo”, Organizacion Mundial del Autismo (OMA), III Congreso Mundial, Monterrey, Mexico, November 3-5, 2010.
“Autism Research from Bench Top to Bedside”, ARI/DAN! Think Tank, Dallas, Texas, January 21-23, 2011.
“Brain Development and the Genesis of Pathology in the Brains of Autistic Individuals”, The Winter Institute (sponsored by the ART-NeuroDevNet Program), Banff, Alberta, Canada March 2-6, 2011.
“Scientific and Ethical Challenges in genetic/biological markers for autism and other developmental conditions”, The Winter Institute (sponsored by the ART-NeuroDevNet Program), Banff, Alberta, Canada March 2-6, 2011.
“Autism: From Desktop to Bedside”, 3rd Annual ORNL Biomedical Science and Engineering Conferece: Image Informatics and Analytics in Biomedicine at the Oak Ridge National Laboratory, Knoxville, TN, March 15, 2011.
“The Role of the Periventricular Germinal Matrix in the Pathogenesis of Autism: Target Site for Exogenous Factors”. IMFAR 2011 Satellite Meeting on the “Maternal Effects on Autism”, San Diego, May 13th, 2011.
“The Hierarchical Organization of the Cerebral Cortex: Minicolumns and Minicolumnopathies”, Neuroscience Combined Grand Rounds, University of Louisville, October 28, 2011.
“Repetitive Transcranial Magnetic Stimulation (rTMS) for the treatment of Autism Spectrum Disorders (ASD)”, Baruth, J.M., Sokhadze, E.M., Sears, L., Casanova, M.F. Mayo Clinic Department of Psychiatry and Psychology, Grand Rounds Lecture, Rochester, Minnesota, April 17, 2012.

“Autism-New Treatments and Latest Research”, Space Coast Disability Council, Hilton Melbourne Rialto Place, Florida, July 21, 2012.

“The Neurobiology of Autism Spectrum Disorders”. International Symposium 2012 of the FRA/CIBERER on Advances in the Biomedical Research of Autism Spectrum Disorders. Barcelona, Spain, September 26, 2012.

“Biomarkers for Autism”, Autism Research Institute Think Tank, April 12-14, 2013.

“Neurological Basis of Autism Spectrum Disorders”. 1st Moscow International Scientific Conference. Autism: Challenge and Solutions. Moscow, April 17-19, 2013.

“Dyslexia: The Big Picture”. Dyslexia and Talent. Emily Hall Tremaine Foundation. New York, April 19-21, 2013.


“Talking to the Experts on Dyslexia”. Interview with Alan Alda. Kildonan School. New York, April 21, 2013.
“Autism: Recent Scientific Advancements”, II International Scientific and Educational Forum: The Person, a Family and Society: History and Development Prospects”, Krasnoyarsk, Russia, November 6-8, 2013.
“Modularidad de la corteza cerebral: aspectos psiauiatricos”, Universidad del Valle, Colombia, 22 de Octubre de 2013
“La neurobiología del autismo”, XV Simposio de investigaciones en salud: discapacidad y ciclo vital. Universidad del Valle, Colombia, 24 de octubre de 2013.
“Organization of the cerebral cortex”, 3 hour seminar, The Pedagogical University of Krasnoyarsk, Siberia, Russia, November 4, 2013.
“Minicolumns and Minicolumnopathies”, 3 hour seminar, The Medical Academy of Krasnoyarsk, Siberia, Russia, November 7, 2013.
“Transcranial magnetic stimulation as a treatment for autism and its neurobiological mechanisms”. 2014 TMS ad ERP Workshop. Shanghai Mental Health Center. Shanghai, China, April 1, 2014
“Autism or autisms?” Neuroscience meeting. Zhejiang University of Science and Technology, China, April 2, 2014
“Introduction to autism in the context of TMS”. Transcranial magnetic stimulation (TMS) therapy for Autism Consensus Conference. Atlanta, GA, May 13, 2014.
“We already know what happens to the brain in autism”. AutismOne, Chicago, May 23, 2014
“The pathophysiology of autism”. Think Tank Discussion on the Brain. AutismOne, Chicago, May 24, 2014.
“La neurobiologia del autismo”. Congreso Internacional: Perspectiva del autismo 30 anos despues. Autismo Burgos, Burgos, Espana, May 29, 2014.
“Implicaciones en el abordaje diagnostico y terapeutico de la neurobiología”. Congreso Internacional: Perspectiva del autismo 30 anos despues. Autismo Burgos, Burgos, Espana, May 30, 2014.
“Autism as a sequence”. American Association of Neuropathologists, Oregon, June 12, 2014
“The heterogeneity of autism”. Grand Rounds. Autism Research Center, Oregon Health and Science University, Oregon, June 12, 2014.
“Heterochronic germinal cell divisions and abnormalities of migration in autism.” Examining a Multi-Systems Approach to Autism and the Environment: Challenges and Opportunities for Research. Hosted by Autism Canada, the Autism Research Institute, and NeuroDevNet. Toronto, Ontario, Canada, June 23-24, 2014.
“Signatures of autism”. EMBO conference on brain development and disorders. Autism and related disorders: from bench to bed and back. La Ciotat 5-8 September, 2014.
“Autism or autisms: clinical heterogeneity and pathophysiological mechanisms”. Grand Rounds in Psychiatry, University of Louisville. September 11, 2014.
“Putative Pathophysiological Mechanisms in Autism”, John D. Wiley Seminar Series, Waisman Center, University of Wisconsin-Madison, September 26, 2014.
“Autism Spectrum Disorders: From Neuropathological Findings to treatment with Transcranial Magnetic Stimulation”, The Romanian Academy of Science, June 26, 2015.
“The Smart State Endowed Char in Childhood Neurotherapeutics: Prospects for Collaboration”, Clemson University School of Health Research, Clemson, South Carolina, September 14, 2015.
“From bench top to bedside: translational research in autism”, Biomedical Research Symposium, University of South Carolina, Columbia, South Carolina, September 21, 2015.
“Autism or autisms: what is the default position?” Grand Rounds, Department of Pediatrics, Greenville Health System, Greenville, South Carolina, September 25, 2015.
“Autism or Autisms: What is the Default Position?” Autism Research Institute (ARI) webinar, September 30, 2015.
“Recent advances in autism research”, Autism Connection, Center for Disability Services, Greenville, South Carolina, October 5, 2015.
GRANT SUPPORT
1987-1990 Rett's Program Project. Research Grant # 1 PO 1 HD-NS 23540-01

Co-Investigator. Total amount for neuropathology $110,272


1992 Stanley Foundation Award

Electron microscopic morphometric study of glio-synaptic relationships in autopsy brains of patients with schizophrenia. Sponsor for Natalya Uranova

Total award $20,000
1993 MCG-GT grant

Neuropathological diagnostics via statistical patterns and artificial neural network recognition of magnetic resonance images. M.F. Casanova, Principal Investigator

Total award $15,000
1993 MCG-GT grant

Epileptic seizure localization using high data rate time and phase information. M.F. Casanova, Terry Brown, Donald Bodnar, Co-Principal Investigators.

Total award $15,000
1994-8 VA Merit Award

Morphological correlates of dementia in schizophrenia. M.F. Casanova, Principal Investigator

Total amount of funding $230,531 for 4 years
1994- Stanley Scholars Award

Total Award $15,000 per year

1996 Principal Investigator: The Efficacy, Safety, and Tolerability of Lazabemide (Ro 19-6327) Versus Placebo, Administered for One Year in Patients with Probable Alzheimer's Disease (NINCDS/ADRDA criteria). Protodigm, LTD, $163,385.
1997-9 Co-Principal Investigator: Cell Mediated Immune Mechanisms in Alopecia Areata, Clinical Research Award, Department of Pathology. The Medical College of Georgia, Co-Principal Investigator, $40,000/year
1998 Approved Open-Labeled Extension (2nd year) for: The Efficacy, Safety, and Tolerability of (Ro 19-6327) Versus Placebo, Administered for One Year in Patients with Probable Alzheimer's Disease (NINCDS/ADRDA criteria). Protodigm, LTD, $34,500.
1998 Co-Principal Investigator: Glaxo Wellcome Protocol SCAA2008: A Multicenter, Double-Blind, Placebo-Controlled Evaluation of the Safety and Efficacy of Lamictal Compared to Placebo and Lithium in the Treatment of an Acute Manic Episode in Patients who have Bipolar Disorder: Incorporating Participation in Genotype Research which is Optional for Both Centers and Patients, $119,549.
1998 Co-Principal Investigator: Olanzapine (LY170053) Protocol F1D-US-HGHQ/ Olanzapine Versus Divalproex in the treatment of Acute Mania. Lilly, $20,720.
1999 Approved Open-Labeled Extension (3rd year) for: The Efficacy, Safety, and Tolerability of (Ro 19-6327) Versus Placebo, Administered for One Year in Patients with Probable Alzheimer's Disease (NINCDS/ADRDA criteria). Protodigm, LTD.
1998-2000 Principal Investigator: NAMI Research Institute: A computer-based analysis of cell columns and perikaryal morphology in the brains of neuroleptic treated schizophrenic patients and normals) $44,000 for 1998-1999 and $46,000 for 1999-2000.
1999-2003 Co-Investigator: Oxidative Cell Injury in First Break Psychotic Patients. RO1, $797,000.


    1. Principal Investigator: Increased Interneuronal Space in the Minicolumns of Major Depression and Bipolar Disorder Brains. Theodore and Vada Stanley Foundation Research Award, $100,000.

2002-3 Principal Investigator: Modular Abnormalities of Brain Organization in Autism, Medical College of Georgia’s Combined Intramural Grants Program, $45,000.


2001-5 Principal Investigator: Comparative Minicolumn Lateralization in Schizophrenia. NIMH, RO1, $1,214,500.
2003-5 Principal Investigator: MRI Correlates of Minicolumnar Pathology in Autism, National Alliance for Autism Research, $60,000 per year ($120,000 total).
2002-6 Principal Investigator: Reduced Interneuronal Space in the Minicolumns of Schizophrenic Brains, NIMH, RO1 MH062654, $874,233.

2002-6 Principal Investigator: Normal human and schizophrenic brain. NIMH, RO1 MH061606, $1,161,270.




    1. Principal Investigator: Modular abnormalities of brain organization in autism, NIMH, RO1 MH069991, $948,389.

2005-2007 Co-Investigator: The Effect of Interneuron Loss on Minicolumnar Structure. COBRE (Molecular Determinants of Developmental Defects), $120,000.


2005-2009 Co-Investigator: Mood stabilizing medications and the inositol signaling system, VA Merit Review, $1,044,200. (Ranga Parthasarathy, PI)
2006 Principal Investigator. Autism Research Center. Collaborative Planning and Developmental Award, University of Louisville $10,000.
2007 Symposium on Cortical Modularity: Normal Development and Pathology.” NAAR/Autism Speaks, $25,000, Casanova MF, PI.
2009-2013 Consultant: Mood stabilizing medications and the inositol signaling system, VA Merit Review (Ranga Parthasarathy, PI).
2009-2013 Principal Investigator: Building a selective inhibitory tone in autism: an

rTMS study. RO1MH086784 $888,000.




    1. Principal Investigator: Gross morphological correlates to the

minicolumnopathy of autism. RO11MH088893 $607,859.


  1. Co-Investigator: Behavioral and psychophysiological study of attentional, perceptual, and emotional processing after treatment with ambient prism lenses and visuo-motor excercises in children with autism spectrum disorder. Autism Research Institute $4,731. (E Sokhadze, PI)




  1. Casanova MF (Co-Principal Investigator): A novel image-based diagnostic system for the accurate diagnosis of autism. Coulter Translational Research Partnership, Wallace H. Coulter Foundation Award. $100,000 (Ayman El-Baz Co-PI)




  1. Casanova MF (Principal Investigator): Anatomical and functional modularity of the cerebral cortex. $8,000. 1R13HD077998-01

2012-2013 Casanova MF (Co-Investigator) Electrophysiological and behavioral outcomes of Auditory Integration Training (AIT) in Autism. Autism Research Institute, $18,000.


2013-2014 Casanova MF (Co-Principal Investigator) Effects of Repetitive Transcranial Magnetic on Gamma Activity and Redox State. Autism Research Institute, $50,000.
2013-2014 Casanova MF (Co-Principal Investigator): A novel image-based diagnostic system for the accurate diagnosis of autism. Coulter Translational Research Partnership, Wallace H. Coulter Foundation Award. $100,000 (Ayman El-Baz Co-PI) Competitice renewal awarded
2013-2015 Casanova MF (Co-Principal Investigator). A novel image-based diagnostic system for the accurate diagnosis of autism. Kentucky Science and Technology Corporation (KSTC): COMMFUND-12-RFP-014, $100,000.
2013-2017 Casanova MF (Consultant): Mood stabilizing medications and the inositol signaling system, VA Merit Review, submitted (Ranga Parthasarathy, PI).
2014-2016 Casanova MF (Co-I): AR130386 - TMS-Based Neuromodulation Therapy for Autonomic Dysfunctions in Autism. Invited for submission.
2014-2015 Casanova MF (Co-I). Investigation of pre-pubertal sex differences in brain morphology, wheel turning and social behavior in mice. Research Initiation Grant, University of Louisville, $3,085. (Cynthia Corbitt PI)


  1. Casanova MF (PI). A quantitative study of pyramidal cells and interneurons in the cerebral cortex of patients with autism spectrum disorders. Autism Research Institute (ARI), $3,000.

2015Casanova MF (PI). A quantitative study of pyramidal cells and interneurons in the cerebral cortex of patients with autism spectrum disorders. Autism Research Institute (ARI), $20,000.


2015 Casanova MF (Co-PI) Computer Assisted Detection Method for Understanding Autism in Young Children. NIH 1 R41 HD084040-01, submitted.
NONFUNDED TRIALS
1997 MF Casanova (Principal Investigator): An Open Label Study of the Efficacy of Topical DMSO/Essential Fatty Acids in the Treatment of Patients with Alopecia Areata.
1998 MF Casanova (Principal Investigator): The Use of 19-Nor 1, 25 Vitamin D3 for the Treatment of Alopecia Areata.

EDUCATION


Introduction to Clinical Research

Fundamentals of Good Clinical Practices

Informed Consent Process

Adverse-Event Reporting

Clinical Trial Management

Drug and Device Regulations

Industry Sponsored Research

Important Topics for Clinical Research Professionals in these Changing Times

Bloodborne Pathogens Training
Patents and Patent Applications:


  1. El-Baz, A, Casanova, M., and Nitzken, M. United States Patent Application serial no. 13/834,231; “Computer Aided Diagnostic System Incorporating 3d Shape Analysis Of The Brain For Identifying Autism And/Or Dyslexia” filed March 15, 2013. Published October 3, 2013 Publication number 2013-0259346-A1, Patent pending: ULRF ref. #11064.

  2. El-Baz AS, Al-Ansary A, Soliman A, Nitzken MJ, Casanova MF. United States Patent Application serial no. 62/024,829; “Computer aided diagnostic system for medical image data” filed July 15, 2014.


Copyrights:

  1. El-Baz, A, Casanova, M., and Nitzken, M., United States Issued Registered Copyright no. TX 7-520-124, “Mesh Diagnostic Software” filed April 5, 2012. ULRF ref. 12063.


Research Disclosure Forms (RDFs):


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