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MHSRS-17-0279 Poster Session 2 - Poster #030
Platelet Lactate Production During Room Temperature Storage Promotes Bacterial Growth
Presentation Author: Dr. Patrick Ketter
Patrick Ketter, PhD1, Bernard Arulanandam, PhD2, LTC(P) Andrew Cap, 1
1U.S. Army Institute of Surgical Research, Joint Base San Antonio, Fort Sam Houston, TX, 2University of Texas at San Antonio, San Antonio, TX
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MHSRS-17-0307 Poster Session 2 - Poster #031
Stored Erythrocytes Alter Endothelial Cell Tissue Factor Expression in Mice
Presentation Author: Dr. Andrew Jung
Andrew D. Jung, MD, Young Kim, MD, MS, William A. Abplanalp, MS, Amy T. Makley, MD, Timothy A. Pritts, MD, PhD, FACS
University of Cincinnati, Cincinnati, OH
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MHSRS-17-0368 Poster Session 2 - Poster #032
Artificial Dense Granules: A Procoagulant Liposomal Formulation for Potential Treatment of Internal Hemorrhage
Presentation Author: Dr. Ying Liu
Alexander J. Donovan, PhD1, Stephanie A. Smith, PhD2, James H. Morrissey, PhD2, Ying Liu, PhD1
1University of Illinois at Chicago, IL, 2University of Illinois at Urbana-Champaign, Urbana,
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MHSRS-17-0382 Poster Session 2 - Poster #033
Computational Model for Hyperfibrinolytic Onset of Acute Traumatic Coagulopathy
Presentation Author: Mr. Tie Bo Wu
Tie Bo Wu1, Wendy Gao1, Sheng Wu, PhD1, Matthew Buoni, PhD1, Thomas Orfeo, PhD2, Kathleen Brummel-Ziedins, PhD2, Mitchell Cohen, MD3, Linda Petzold, PhD1
1Unversity of California Santa Barbara, Santa Barbara, CA, 2University of Vermont, Burlington, Vermont, 3Denver Health and Hospital Authority
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MHSRS-17-0398 Poster Session 2 - Poster #034
Increased Mitochondrial DNA in an ECMO Model is Associated with Loss of Platelet Function
Presentation Author: Mr. Colby McIntosh
James A. Bynum, PhD, Andrew D. Meyer, MD, PhD, Daniel Darlington, PhD, Colby S. McIntosh, BS, Grantham C. Peltier, MS, Ashley S. Taylor, BA, Michael A. Meledeo, PhD, Andrew P. Cap, MD, PhD
U.S. Army Institute of Surgical Research, Fort Sam Houston, San Antonio, TX
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MHSRS-17-0410 Poster Session 2 - Poster #035
Spray-Dried Plasma Deficient in High Molecular Weight Multimers of Von Willebrand Factor Retains Hemostatic Properties
Presentation Author: Dr. Michael Meledeo
Michael Meledeo, PhD1, Qiyong Peter Liu, PhD2,Grantham Peltier, MS1, Ryan Carney, MS2, Ashley Taylor, BA1, Colby McIntosh, BS1, James Bynum, PhD1, Andrew Cap, MD, PhD1
1U.S. Army Institute of Surgical Research, Joint Base San Antonio, Fort Sam Houston, TX, 2Velico Medical, Beverly, MA
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MHSRS-17-0428 Poster Session 2 - Poster #036
The Interaction of Platelet Agonist and PGI2 for Regulation of Intracellular cAMP
Presentation Author: Dr. Daniel Darlington
Daniel N. Darlington, PhD1,2, Xiaowu Wu, MD1,2, Andres S. Penagosnino1, Andrew P. Cap, MD, PhD 1,2
1U.S. Army Institute of Surgical Research, Fort Sam Houston, TX, 2University of Texas Health Science Center, San Antonio, TX
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MHSRS-17-0432 Poster Session 2 - Poster #037
The Interaction of Platelet Agonist and NO for Regulation of Intracellular cGMP
Presentation Author: Dr. Daniel Darlington
Daniel N. Darlington, PhD1,2, Xiaowu Wu, MD1,2, Josue Garciamarcano1, Andrew P. Cap, MD PhD1,2
1U.S. Army Institute of Surgical Research, Fort Sam Houston, TX, 2University of Texas Health Science Center, San Antonio, TX
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MHSRS-17-0437 Poster Session 2 - Poster #038
Toll-like Receptor 2 (TLR2) Mediates Platelet Aggregation
Presentation Author: SPC Harvey Harper
Harvey L. Harper Jr, BS1, Xiaowu Wu, MD1,2, Aaron M Lewis, MD2, Daniel N. Darlington, PhD1,2, Andrew P. Cap, ,MD, PhD1,2, Martin G Schwacha, PhD1,2
1U.S. Army Institute of Surgical Research, Fort Sam Houston, TX, 2University of Texas Health Science Center, San Antonio, TX
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MHSRS-17-0449 Poster Session 2 - Poster #039
The Effect of Rat Mesenchymal Stem Cells on Hemostatic and Platelet Function
Presentation Author: Dr. Xiaowu Wu
Xiaowu Wu, MD1,2, Daniel N. Darlington, PhD1,2, Bin Liu, BS1, Jeffery D. Keesee, BS1, Robbie K. Montgomery, MS1, Andres S. Penagosnino1, Josue Garciamarcano1, Andrew P. Cap, MD, PhD1,2
1U.S. Army Institute of Surgical Research, Fort Sam Houston, TX, 2University of Texas Health Science Center, San Antonio, TX
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MHSRS-17-0451 Poster Session 2 - Poster #040
Development of Prostate Cancer Gene Expression Panel with Potential Diagnostic Utility in African American and Caucasian American
Presentation Author: Dr. Indu Kohaar
Indu Kohaar, PhD1, Lakshmi Ravindranath, BA1, Sreedatta Banerjee, BS1, Yongmei Chen, MS1, Amina Ali, BS1, Jacob Kagan, PhD2, Sudhir Srivastava, PhD2, Albert Dobi, PhD1, David McLeod, MD1,3, Inger L. Rosner, MD1,3, Shiv Srivastava, PhD1, Gyorgy Petrovics, PhD1
1Center for Prostate Disease Research, Rockville, MD, 2National Cancer Institute, National Institutes of Health, Bethesda, MD, 3Walter Reed National Military Medical Center, Bethesda, MD
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MHSRS-17-0452 Poster Session 2 - Poster #041
The Effect of Hypoxia on Tissue Factor Expression and Procoagulant Properties of Rat Mesenchymal Stem Cells
Presentation Author: Dr. Xiaowu Wu
Xiaowu Wu, MD1,2, Daniel N. Darlington, PhD1,2, Bin Liu, BS1, Jeffery D. Keesee, BS1, Robbie K. Montgomery, MS1, Andres S. Penagosnino1, Josue Garciamarcano1, Andrew P. Cap MD, PhD1,2
1U.S. Army Institute of Surgical Research, Fort Sam Houston, TX, 2University of Texas Health Science Center, San Antonio, TX
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MHSRS-17-0456 Poster Session 2 - Poster #042
Comparison of Mesenchymal Stem Cell Potency Assays
Presentation Author: Dr. Barbara Christy
Barbara A. Christy, PhD, Maryanne C. Herzig, PhD, Christopher P. Delavan, MS, Larry E. Estlack, BS, Robbie K. Montgomery, MS, James A. Bynum, PhD, Andrew P. Cap, MD, PhD
U.S. Army Institute of Surgical Research, Joint Base San Antonio, San Antonio, TX
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MHSRS-17-0458 Poster Session 2 - Poster #043
Expression of Genes Encoding Tissue Factor Pathway Proteins in Human Mesenchymal Stem Cells
Presentation Author: Mr. Larry Estlack
Larry E. Estlack, BS, Maryanne C. Herzig, PhD, Barbara A. Christy, PhD, Robbie K. Montgomery, MS, Christopher Delavan, MS, James A. Bynum, PhD, Kristin M. Reddoch, PhD, Andrew P. Cap, MD, PhD
U.S. Army Institute of Surgical Research, Joint Base San Antonio, San Antonio, TX
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MHSRS-17-0487 Poster Session 2 - Poster #044
in Vivo Viability of Extended 10-Day 4 degrees C Stored Autologous Platelets
Presentation Author: Dr. Sherrill Slichter
Sherrill J. Slichter, MD1,2, Lynda Fitzpatrick, RN1, Irena Gettinger, BA1, S. Lawrence Bailey, BS1, Todd Christoffel, MT(ASCP)1
1Bloodworks Northwest, Seattle, WA, 2University of Washington School of Medicine, Seattle, WA
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MHSRS-17-0502 Poster Session 2 - Poster #045
Successful Validation in a Deployed Setting of the Trima Accel® Apheresis Instrument for Production of Plasma- and PAS-stored Apheresis Platelets
Presentation Author: LTC Jason Corley
LTC Jason Corley, MS1, Lt Col Angelica Black, MS2, LTC Jose Quesada, MS3, LTC Andrew Cap, MD, PhD4, Maj Edward Griffin, MBA, MS5, Lt Col Carol West6, Lt Col Kathryn Shaw, MS7, COL Audra Taylor, MS1
1Army Blood Program, Fort Sam Houston, TX, 22nd Medical Support Squadron, Barksdale Air Force Base, Louisiana, 3U.S. Central Command, Joint Blood Program, Al Udeid Air Base, Qatar, 4U.S. Army Institute of Surgical Research, Fort Sam Houston, TX, 560th Diagnostics and Therapeutics Squadron, Travis Air Force Base, CA, 6379th Expeditionary Medical Group, Al Udeid Air Base, Qatar, 7Air Force Blood Program, Port San Antonio, TX
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MHSRS-17-0515 Poster Session 2 - Poster #046
Increased Frequency of Germline BRCA2 Mutations in Racially Diverse Prostate Cancer Patients with Aggressive Disease or Metastasis Progression
Presentation Author: Dr. Gyorgy Petrovics
Gyorgy Petrovics, PhD2, Douglas Price6, Hong Lou1, Yongmei Chen, MS2, Lisa Garland1, Sara Bass1, Kristine Jones1, Indu Kohaar, PhD2, Anima Ali, BS2,3, Lakshmi Ravindranath, BS2, Denise Young, BS2, Jennifer Cullen, PhD2, Tiffany Dorsey6, Isabell A. Sesterhenn, MD5,
Stephen A. Brassell, MD3, Inger L. Rosner, MD3, Doug Ross6, William Dahut, MD6, Stefan Ambs, PhD6, Shiv Srivastava, PhD2, Michael Dean,PhD1
1National Cancer Institute, Leidos Biomedical Research Inc., Bethesda, MD, 2Uniformed Services University of the Health Sciences, Rockville, MD, 3Walter Reed National Military Medical Center, Bethesda, MD, 4National Cancer Institute, Rockville, MD, 5Joint Pathology Center, Silver Spring, MD, 6National Cancer Institute, National Institutes of Health, Bethesda, MD
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MHSRS-17-0553 Poster Session 2 - Poster #047
Increased Plasma FXIII Binding in Cold-Stored Platelets Confers Resistance to Fibrinolysis
Presentation Author: Ms. Prajeeda Nair
Prajeeda M. Nair, MS1,2, Shaunak G. Pandya,PhD1, Jeffery Keesee, BS2, Ron S. Bryant, MT2, Andrew P. Cap, MD, PhD2, Anand K. Ramasubramanian, PhD3
1University of Texas at San Antonio, San Antonio, TX, 2U.S. Army Institute of Surgical Research, Fort Sam Houston, TX, 3San José State University, San José, CA
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MHSRS-17-0563 Poster Session 2 - Poster #048
A Streamlined Mixed Lymphocyte Reaction (MLR) Assay for Evaluation of Human Mesenchymal Stem Cell Immunomodulation Activity
Presentation Author: Mr. Christopher Delavan
Christopher Delavan, MS, Maryanne Herzig, PhD, Barbara Christy, PhD, James Bynum, PhD, Andrew Cap, MD, PhD
U.S. Army Institute of Surgical Research, Joint Base San Antonio, Fort Sam Houston, TX
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MHSRS-17-0580 Poster Session 2 - Poster #049
Abnormal Calcium Levels During Trauma Resuscitation Are Associated with Increased Mortality, Increased Blood Product Use, and Greater Hospital Resource Consumption
Presentation Author: Lt Col Jeremy Cannon
Jeremy W. Cannon MD1,2, Emily J. MacKay DO1, Michael D. Stubna PhD3, Daniel N. Holena MD1, Patrick M. Reilly MD1, Mark J. Seamon MD1, Brian P. Smith MD1, Lewis J. Kaplan MD1,4
1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Uniformed Services University of the Health Sciences, Bethesda, MD, 3Mountain Track Apps, Philadelphia, PA, 4Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA
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MHSRS-17-0591 Poster Session 2 - Poster #050
Umbilical Cord Blood-Derived Platelet Lysate (UCB-PL) – A Xeno-Free Alternative for Large-Scale Cell Expansion
Presentation Author: Dr. Anand Srinivasan
Anand Srinivasan1, Scott Jones2, Andrew P. Cap1
1U.S. Army Institute of Surgical Research, Fort Sam Houston, TX, 2BioBridge Global, San Antonio, TX
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MHSRS-17-0697 Poster Session 2 - Poster #051
Assessment of Cell Quality Following Riboflavin and Ultraviolet Light Treatment of Whole Blood in Citrate-Phosphate-Dextrose-Adenine Anticoagulant
Presentation Author: Dr. Susan Yonemura
Susan Yonemura, PhD, Suzann Doane, Jane Gosney, Nick Hovenga, Melissa Tran, Heather Pidcoke, MD, PhD
Terumo BCT, Lakewood, CO
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MHSRS-17-0698 Poster Session 2 - Poster #052
Assessment of Pathogen Reduction Capacity Following Riboflavin and Ultraviolet Light Treatment of Whole Blood in Citrate-Phosphate-Dextrose-Adenine Anticoagulant
Presentation Author: Dr. Susan Yonemura
Susan Yonemura, PhD, Suzann Doane, Jane Gosney, Molly Sutton, Etienne Toko, Heather Pidcoke, MD, PhD
Terumo BCT, Lakewood, CO
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MHSRS-17-0711 Poster Session 2 - Poster #053
Cryopreserved Sheep Platelet Concentrates: Hemostatically Efficient and Suitable for Transfusion Research
Presentation Author: COL Michael C Reade
Gabriela Simonova, Ms1-3, Sanne Pedersen, MS2, COL Michael C Reade3,4, Lacey Johnson, PhD1, Melinda M Dean, PhD1,3, Denese C Marks, PhD1, John-Paul Tung, PhD1-3
1Australian Red Cross Blood Service, Brisbane/Sydney, Australia, 2The Prince Charles Hospital, Brisbane, Australia, 3School of Medicine, University of Queensland, Brisbane, Australia, 4Joint Health Command, Australian Defence Force, Canberra, Australia
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MHSRS-17-0716 Poster Session 2 - Poster #054
Combination Therapy with Red Blood Cell Substitute and Platelet Substitute Effectively Rescues Rabbits from Massive Hemorrhage Caused by Thrombocytopenic Coagulopathy
Presentation Author: Dr. Manabu Kinoshita
Kosuke Hagisawa1, Hiromi Sakai2, Shinji Takeoka3, Daizoh Saitoh1, Nariyoshi Shinomiya1, Shuhji Seki1
1National Defense Medical College Japan, Tokorozawa, Japan, 2Nara Medical University, Nara, Japan, 3Waseda University, Tokyo, Japan
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MHSRS-17-0923 Poster Session 2 - Poster #055
Prolonging Shelf Life of Platelets by Near Infrared and Blue Lasers
Presentation Author: Dr. Mei Wu
Min Lu, Ph.D, Qi Zhang, PhD, Tianhong Dai, PhD,
Harvard Medical School, Boston, MA
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MHSRS-17-0980 Poster Session 2 - Poster #056
Secreted Protein Acidic and Rich in Cysteine (SPARC) Autoantibodies in Sera of Prostate Cancer Patients
Presentation Author: CPT Andy Martinez
Andy J. Martinez, MD1, Anshu Rastogi, PhD2, Amina Ali, BS1, Shyh-Han Tan, PhD2, Jennifer Cullen, PhD2, Yongmei Chen, MS2, Gyorgy Petrovics, PhD2, Albert Dobi, PhD2, Lakshmi Ravindranath, BS2, Thomas Gerald, MD1, Denise Young, BS2, Isabell A. Sesterhenn, MD3, Jacob Kagan, PhD4, Sudhir Srivastava, PhD4, David G. McLeod, MD2, Inger L. Rosner, MD1, Shiv Srivastava, PhD2, Alagarsamy Srinivasan, PhD2
1Walter Reed National Military Medical Center, Bethesda, MD, 2Uniformed Services University of the Health Sciences, Bethesda, MD, 3Joint Pathology Center, Silver Spring, MD, 4National Cancer Institute, National Institutes of Health, Bethesda, MD
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MHSRS-17-0981 Poster Session 2 - Poster #057
Inertial Microfluidics-Based Platform for Portable Platelet Apheresis
Presentation Author: Dr. Ketan Bhatt
Ketan Bhatt, PhD1, Hongjun Song, PhD1, Charles Garson, MS1, Prabhakar Pandian, PhD1, Kapil Pant, PhD1, Edward Scott, MD2, CAPT Sean Hussey, MD3
1Computational Fluid Dynamics Research Corporation, Huntsville, AL, 2Key Biologics LLC, Memphis, TN, 3U.S. Marine Corps I Marine Expeditionary Force, Camp Pendelton, CA
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MHSRS-17-1040 Poster Session 2 - Poster #058
Systems Biology Based Tools for Modeling Platelet Storage Lesion for Optimal Blood Transfusions
Presentation Author: Dr. Andrzej Przekwas
Andrzej Przekwas1, Mahadevabharath R. Somayaji1, Debarun Das1, Zhijian J. Chen1, Frank J. Lebeda2, Ranjan K. Dash3, Anand K. Ramasubramanian4
1Computational Fluid Dynamics Research Corporation, Huntsville, AL, 2U.S. Army Medical Research and Materiel Command, Fort Detrick, MD, 3Medical College of Wisconsin, Milwaukee, WI, 4San Jose State University, San Jose, CA
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MHSRS-17-1059 Poster Session 2 - Poster #059
Rapid and High-Throughput Microfluidic Sorters for Stem Cells Isolation
Presentation Author: Dr. Lap Man Lee
Lap Man Lee1, Hongjun Song1, Jenna Rosano1, Yi, Wang1, Charles Garson1, Prabhakar Pandian1, Kapil Pant1, George J. Klarmann2, Luis M. Alvarez2,3, Eva Lai4,5
1Computational Fluid Dynamics Research Corporation, Huntsville, AL, 2National Cancer Institute, Frederick, MD, 3U.S. Military Academy, West Point, NY, 4Johns Hopkins University, Baltimore, MD, 5U.S. Army Medical Research and Materiel Command, Fort Detrick, MD
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MHSRS-17-1099 Poster Session 2 - Poster #060
On-track to Producing cGMP-Compliant Human Platelets from induced Pluripotent Stem Cells for Far-Forward Military Settings
Presentation Author: Dr. Jonathan Thon
Jonathan N. Thon1,2,3, Brad Dykstra1,2,3, Lea Beaulieu3, Christian Peters,3 Joseph Italiano Jr.1,2,3
1Brigham and Women's Hospital, MA, 2Harvard Medical School, Boston, MA, 3Platelet BioGenesis, Boston, MA
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MHSRS-17-1130 Poster Session 2 - Poster #061
Novel Wound Dressings Containing Broad Spectrum Antimicrobial and Blood Coagulation Agents for Severe Trauma-Induced Hemorrhaging and Blast Injuries
Presentation Author: Dr. Marek Urban
Marek W. Urban, PhD, Robert A. Latour, PhD
Clemson University, Clemson, SC
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MHSRS-17-1418 Poster Session 2 - Poster #062
Whole Blood and Low Titer Testing in Support of Trauma Resuscitation During Combat Operations
Presentation Author: Col Audra Taylor
COL Audra Taylor1, LTC Jason Corley1, LTC(P) Andrew Cap2, LTC Ethan Miles3, MAJ Andrew Fisher4, Sheila Rudesheim5, CPT Jacquelyn Messenger6, Todd Cosgrove6, MAJ James Burke7, Karen Royster1, David Reiber1
1U.S. Army Medical Command, Fort Sam Houston, TX, 2U.S. Army Institute of Surgical Research, Fort Sam Houston, TX, 375th Ranger Regiment, Fort Benning, GA, 4Texas A&M University College of Medicine, Bryan, TX, 5Sullivan Memorial Blood Center, Fort Benning, GA, 6Madigan Army Medical Center, Tacoma, WA, 7Fort Leonard Wood Blood Donor Center, Ft. Leonard Wood, MO
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MHSRS-17-1574 Poster Session 2 - Poster #063
Treating Temporary Vascular Shunts with a Slippery Surface to Reduce Thrombosis
Presentation Author: Dr. Michael Super
Michael Super, PhD, Thomas Doyle, Shanda Lightbown, Kelly Smith, Sami Rifai, Donald Ingber, MD, PhD
Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA
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MHSRS-17-1646 Poster Session 2 - Poster #064
Synergistic Effects of Acidosis, Factor XIII, and Platelets on Fibrin Viscoelasticity
Presentation Author: Dr. Laura Haynes
Laura M. Haynes, PhD, Dana E. Bourne, BS, Matthew Gissel, MS, Thomas Orfeo, PhD, Kathleen E. Brummel-Ziedins, PhD
University of Vermont, Colchester, VT
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MHSRS-17-1722 Poster Session 2 - Poster #065
Dynamic Modeling of Fibrinolysis using Reduced Order Effective Kinetic Models
Presentation Author: Ms. Rachel LeCover
Rachel LeCover1, Maria Cristina Bravo2, Thomas Orfeo2, Kathleen E. Brummel-Ziedins2, Jeffrey D. Varner1
1Cornell University, Ithica, NY, 2University of Vermont, Burlington, VT
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MHSRS-17-1778 Poster Session 2 - Poster #066
Novel Cold Chain Containers for Blood and Pharmaceutical Product Transport
Presentation Author: Dr. Todd McAdams
Todd McAdams, PhD
Resodyn Corporation, Butte, MD
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MHSRS-17-1791 Poster Session 2 - Poster #067
Implementation of Uncrossmatched Whole Blood During Trauma Resuscitations in a Civilian Level 1 Trauma Center
Presentation Author: Ms. Catherine Zatorski
Catherine Zatorski, BA1, Charlene Bierl, MD, PhD2, John Porter, MD1,2, Joshua P. Hazelton, DO1,2
1Cooper Medical School of Rowan University, Camden, NJ, 2Cooper University Hospital, Camden, NJ
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MHSRS-17-1861 Poster Session 2 - Poster #068
Integration of Platelet-Rich Plasma with Osteoconductive Material for Bone Regeneration and Treatment of Inflammatory Bone Lytic Lesion in Periodontitis
Presentation Author: Dr. Toshihisa Kawai
Toshihisa Kawai, DDS, PhD1, Umadevi Kandalam, PhD1, Kenta Yamamoto, DDS, PhD1, Richard J. Miron, DDS PhD1, Alexandru Movila, PhD2
1Nova Southeastern University, College of Dental Medicine, Fort Lauderdale, FL, 2The Forsyth Institute, Cambridge, MA
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MHSRS-17-1886 Poster Session 2 - Poster #069
Blood Group and Coagulation After Injury: Does ABO Matter?
Presentation Author: Mr. Ryan Kunitake
Ryan Kunitake, BA1, Lucy Z. Kornblith, MD1, Anamaria J. Robles, MD1, Amanda S. Conroy, BA1, Mitchell J. Cohen, MD2, Rachael A. Callcut, MD, MSPH1
1Univeristy of California San Francisco, Zuckerberg San Francisco General Hospital, San Francisco, CA 2Denver Health Medical Center, Denver, CO
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