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HEMORRHAGE CONTROL & RESUSCITATION



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HEMORRHAGE CONTROL & RESUSCITATION


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MHSRS-17-0016 Poster Session 2 - Poster #268
Efficacy and Safety of a Novel Abdominal Aortic Tourniquet Device for the Control of Pelvic and Lower Extremity Hemorrhage in a Swine Model
Presentation Author: Dr. Bradford Reynolds

Richard Schwartz, MD1, Bradford Reynolds, MD1, Charles Moore, MD2, Eric Greenfield, DO3, John Croushorn, MD1, Brooke Lerner, PhD4, Ian Wedmore, MD5, Steve Holsten, MD1, John Beatty, MD6, John McManus, MD1, Matt Lyon1



1Medical College of Georgia at Augusta University, Augusta, GA, 2Fort Stewart/Hunter Army Air Force Base, Savannah, GA, 3Huntsville Hospital, Huntsville, AL, 4Medical College of Wisconsin, Milwaukee, WI, 5Madigan Army Medical Center, Tacoma, WA, 6East Tennessee State University, Johnson City, TN

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MHSRS-17-0047 Poster Session 2 - Poster #269
Smartphone-Based Mobile Thermal Imaging Technology to Assess Limb Perfusion and Tourniquet Effectiveness Under Normal and Blackout Conditions
Presentation Author: CPT Morgan Barron

Morgan R. BarronD, John P. Kuckelman, DO, John M. McClellan, MD, Michael J. Derickson, MD, Cody J. Phillips, DO, Shannon T. Marko, DVM, Joshua P. Smith, DO, Matthew J. Eckert, MD, Matthew J. Martin, MD

Madigan Army Medical Center, Tacoma, WA


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MHSRS-17-0083 Poster Session 2 - Poster #270
Investigation of Intravenous Hydroxocobalmin Compared to Hextend for Resuscitation in a Swine Model of Uncontrolled Hemorrhagic Shock: A Preliminary Report
Presentation Author: Dr. Joseph Maddry

Maj Joseph Maddry, USAF1,2, Normalynn Garrett, PhD, CRNA, FAAN1, Maria Castaneda, MS1, Susan Boudreau, RN, BSN1, Kaysie Canellis, ALAT1, Vikhyat Bebarta, MD3



1Center for Research Excellence in Science and Technology, Joint Base San Antonio, Fort Sam Houston, TX, 259th MDW, Joint Base San Antonio, Fort Sam Houston, TX, 3University of Colorado, Denver, TX

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MHSRS-17-0182 Poster Session 2 - Poster #271
Surviving Blood Loss Under Austere Conditions: The Salutary Effects of Ethynyl Estradiol-3-sulfate Following Severe Blood Loss (without Fluid Resuscitation) Are Mediated Specifically via the Estrogen Receptors (ERs)
Presentation Author: Dr. Shaolong Yang

Shaolong Yang, MD, Shunhua Hu, MD, William J. Hubbard, PhD, Irshad H. Chaudry, PhD

University of Alabama at Birmingham, Birmingham, AL


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MHSRS-17-0188 Poster Session 2 - Poster #272
Duration of Shock, but Not Magnitude or Tissue Injury, Exacerbates Endothelial Dysfunction and Systemic Inflammation
Presentation Author: Dr. Alexander Burdette

Alexander Burdette, PhD, Antonio Macko, PhD, Madelaine Paredes, PhD, CDR Forest Sheppard

Naval Medical Research Unit San Antonio, Joint Base San Antonio, Fort Sam Houston, TX


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MHSRS-17-0190 Poster Session 2 - Poster #273
Early Organ Damage Escalates with Increasing Injury Severity and Delayed Resuscitation
Presentation Author: Dr. Alexander Burdette

Alexander J. Burdette, PhD, Antonio Macko, PhD, Madelaine Paredes, PhD, CDR Forest Sheppard

Naval Medical Research Unit San Antonio, Joint Base San Antonio, Fort Sam Houston, TX


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MHSRS-17-0233 Poster Session 2 - Poster #274
Mobile Thermal Imaging Technology Allows Rapid Assessment of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in Hemorrhage and Blackout Conditions
Presentation Author: Capt Morgan Barron

Morgan Barron, MD, John Kuckelman, DO, John McClellan, MD, Michael Derickson, MD, Cody Phillips, DO, Shannon Marko, DVM, Joshua Smith, DO, Matthew Eckert, MD, Matthew Martin, MD

Madigan Army Medical Center, Tacoma, WA


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MHSRS-17-0343 Poster Session 2 - Poster #275
Systemic and Microcirculatory Assessment of Severe Hemorrhagic Shock and Resuscitation Using SANGUINATE
Presentation Author: Dr. Bjorn Song

Bjorn K. Song1,Ramon F. Cestero2, Kevin Ward3, Peter Buontempo4, Ronald Jubin4, Abe Abuchowski4, William H. Nugent1



1Song Biotechnologies, Baltimore, MD, 2University of Texas Health San Antonio, San Antonio, TX, 3University of Michigan Medical School, Ann Arbor, MI, 4Prolong Pharmaceuticals, South Plainfield, NJ

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MHSRS-17-0366 Poster Session 2 - Poster #276
Comparison Between the Abdominal Aortic and Junctional Tourniquet and Reboa on Tissue Inflammatory and Oxidant Stress Markers in a Swine Uncontrolled Hemorrhage Model
Presentation Author: Dr. Michael Dubick

Michael A Dubick PhD, Johnny L Barr MS, Rodolfo De Guzman MT, Theo W Thomas BS, I Amy Polykratis BS, SPC Jorhan Ocasio Rosa BS, SPC Jose J Bernal MT, M Dale Prince BS

U.S. Army Institute of Surgical Research, Joint Base San Antonio, Fort Sam Houston, TX


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MHSRS-17-0416 Poster Session 2 - Poster #277
The Use of the Abdominal Aortic and Junctional Tourniquet as an Adjunct to Cardiopulmonary Resuscitation Following Traumatic Cardiac Arrest in Swine
Presentation Author: Ms. Jennifer Cox

Jennifer Cox, BS1, Jason Rall, PhD1, Joseph Maddry, MD1,2



159th Medical Wing, Joint Base San Antonio,-Fort Sam Houston, TX, 2Air Force En route Care Research Center, U.S. Army Institute of Surgical Research/59th MDW, Joint Base San Antonio, Fort Sam Houston, TX

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MHSRS-17-0440 Poster Session 2 - Poster #278
Benchmarking Emergency Department Thoracotomy Using Video Review to Define Procedural Norms
Presentation Author: Lt Col Jeremy Cannon

Jeremy Cannon MD1,2, Ryan Dumas MD1, Kristen Chreiman MSN1, Matthew Goldshore MD1, Mark Seamon MD1, Patrick Reilly MD1, Jason Christie MD MCSE1, Daniel Holena MD MSCE1



1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Uniformed Services University of the Health Sciences, Bethesda, MD

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MHSRS-17-0447 Poster Session 2 - Poster #279
Usability Evaluation of a Humeral Head Intraosseous Training System
Presentation Author: Dr. Teresita Sotomayor

Teresita M. Sotomayor, PhD1, Angela M. Alban, MS2



1U.S. Army Research Laboratory HRED-ATSD, Orlando, FL, 2Simetri, Inc., Winter Park, FL

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MHSRS-17-0465 Poster Session 2 - Poster #280
Myeloid Cell Toll-like Receptor (TLR) Expression is Increased Following Trauma-Induced Acute Lung Injury
Presentation Author: Dr. Martin Schwacha

Martin G. Schwacha, PhD1,2, Meenakshi Rani, PhD1, Shannon R. Scroggins, MS1, Eva M. Galvan, MD1, Susannah E. Nicholson, MD1, Andrew P. Cap, MD, PhD1,2



1University of Texas Health Science Center at San Antonio, San Antonio TX, 2U.S. Army Institute of Surgical Research, Fort Sam Houston, TX

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MHSRS-17-0536 Poster Session 2 - Poster #281
Dose Responses of Fibrinogen Concentrate on Coagulation in Human Plasma in Vitro
Presentation Author: Dr. Wenjun Martini

Wenjun Martini, PhD, Rodolfo De Guzman, MT, Cassandra Rodriguez, BS, Leticia Bice, DVM, Irene Polykratis, BS, Andrew Cap, MD, PhD, Michael Dubick, PhD

U.S. Army Institute of Surgical Research, Joint Base San Antonio, Fort Sam Houston, TX


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MHSRS-17-0538 Poster Session 2 - Poster #282
Resuscitative Effects of Fibrinogen Concentrate and FFP After Traumatic Hemorrhage in Pigs
Presentation Author: Dr. Wenjun Martini

Wenjun Martini, PhD, Kevin Chung, MD, Michael Dubick, PhD

U.S. Army Institute of Surgical Research, Joint Base San Antonio, Fort Sam Houston, TX


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MHSRS-17-0547 Poster Session 2 - Poster #283
Experimentally Approaching Trauma Induced Coagulopathy
Presentation Author: Dr. Wenjun Martini

Wenjun Martini, PhD

U.S. Army Institute of Surgical Research, Joint Base San Antonio, Fort Sam Houston, TX


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MHSRS-17-0551 Poster Session 2 - Poster #284
Effect of Resuscitation Fluid on Edema Formation in Jejunal Tissue of a Swine Uncontrolled Hemorrhage Model Treated with Either Abdominal Aortic and Junctional Tourniquet (AAJT) Or Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)
Presentation Author: Ms. Amy Polykratis

Amy Polykratis, BS1, Dale Prince, BS1, Rodolfo de Guzman, MLT1, Jorhan Ocasio-Rosa, BS1, Jose Bernal, MLT1, Johnny Barr, MS1, Theo Thomas, BS1, Michael Dubick, PhD1

U.S. Army Institute of Surgical Research, Joint Base San Antonio, Fort Sam Houston, TX


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MHSRS-17-0554 Poster Session 2 - Poster #285
Multi-Functional Coagulation Sensing at the Point-of-Care
Presentation Author: Dr. Markandey Tripathi

Diane M Tshikudi, MS1, Markandey M Tripathi, PhD1, Alexandra G. Wirth, BS1, Elizabeth M Van Cott, MD2, Seemantini K Nadkarni, PhD1



1Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Massachusetts General Hospital, Harvard Medical School, Boston, MA

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MHSRS-17-0571 Poster Session 2 - Poster #286
Shock Volume: An Integration of Cumulative Hypoperfusion Predicts Organ Dysfunction in Multiply Injured Patients
Presentation Author: Dr. Todd McKinley

Greg E. Gaski MD,Tyler McCarroll MS, Cameron Metzger MS, Jeremy Adler MS, Krista Brown MSc, Lauren Hill BSc, Benjamin L. Zarzaur MD, Stephanie A. Savage MD, Todd O. McKinley MD

Indiana University School of Medicine, Indianapolis, IN


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MHSRS-17-0582 Poster Session 2 - Poster #287
Evaluation of Blood Chemistry Pertaining to Renal Function in a Swine Uncontrolled Hemorrhage Model Treated with the Abdominal Aortic and Junctional Tourniquet or Resuscitative Balloon Occlusion of the Aorta and Resuscitated with Shed Whole Blood.
Presentation Author: Mr. Rodolfo de Guzman Jr.

Rodlfo de Guzman Jr., MT, I Amy Polykratis, BS, M Dale Prince, BS, Jorhan Ocasio, BS, Jose Bernal, MLT, Johnny Barr, MS, Theo Thomas, BS, Michael Dubick, PhD

U.S. Army Institute of Surgical Research, Joint Base San Antonio, Fort Sam Houston, TX


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MHSRS-17-0628 Poster Session 2 - Poster #288
Analysis of Crystalloid Usage from Injury to Role 2 Facility Discharge During the Afghanistan Conflict
Presentation Author: Mrs. krystal Valdez-delgado

Krystal Valdez-Delgado BSN, RN1,LTC(P) Jennifer Gurney2, Amanda Staudt, PhD1, Mithun Suresh, MD1, Jennifer Trevino, MBA1, Nicole Caldwell, RN1, LTC Andrew Cap1, COL Shawn Nessen1, COL Elizabeth Mann-Salinas1



1U.S. Army Institute of Surgical Research, Joint Base San Antonio, Fort Sam Houston, TX, 2Joint Trauma System, Joint Base San Antonio-Fort Sam Houston, TX

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MHSRS-17-0654 Poster Session 2 - Poster #289
Effects of Sanguinate on Systemic and Microcirculatory Variables in a Model of Prolonged Ischemic Shock
Presentation Author: Dr. William Nugent

William H. Nugent1, Ramon F. Cestero2, Kevin Ward3, Ronald Jubin4, Abe Abuchowski4, Bjorn K. Song1



1Song Biotechnologies, Baltimore, MD, 2University of Texas Health San Antonio, San Antonio, TX, 3University of Michigan Medical School, Ann Arbor, MI, 4Prolong Pharmaceuticals, South Plainfield, NJ

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MHSRS-17-0745 Poster Session 2 - Poster #290
Application of the iTClamp™ in Conjunction with Hemostatic Agents for Control of Lethal Hemorrhage in Swine
Presentation Author: LCDR Sean Stuart

LCDR Sean M. Stuart, Julie B. Mclean, PhD, LT Robert B. McLendon, Alexandra C. Walchak, MPH, CVT, Gregory J. Zarow, PhD, LCDR Sean P. Conley

Combat Trauma Research Group, Naval Medical Center Portsmouth, Portsmouth, VA


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MHSRS-17-0789 Poster Session 2 - Poster #291
Poly-trauma without Specific Head Trauma Elevates Biomarkers of Traumatic Brain Injury (TBI): Implications for Treatment.
Presentation Author: Dr. Madelaine Paredes

R. Madelaine Paredes PhD, LT Neal McNeal, Savannah A. Green, BA, CDR Jacob J. Glaser, CDR Forest R. Sheppard



Naval Medical Research Unit San Antonio, Joint Base San Antonio,-Ft. Sam Houston, TX

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MHSRS-17-0792 Poster Session 2 - Poster #292
The Sequence of Blood and Crystalloid in the First Hour of Resuscitation Determines The Post-Injury Inflammatory Response in a NHP Severe Poly-Traumatic Hemorrhagic Shock Model
Presentation Author: Dr. Madelaine Paredes

R. Madelaine Paredes, Alexander Burdette, Tony Macko, Douglas Tadaki, Forest Sheppard

Naval Medical Research Unit San Antonio, Joint Base San Antonio,-Ft. Sam Houston, TX

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MHSRS-17-0824 Poster Session 2 - Poster #293
Complement Activation in a Non-Human Primate (Rhesus Macaque) Model of Poly-Traumatic Hemorrhage: A Possible Therapeutic Target?
Presentation Author: Dr. Madelaine Paredes

Madelaine Paredes PhD1, Sarah Stubbs, BS1, Leasha Schaub, MS1, G. Andrew Pratt III, MS1, Jurandir J. Dallelucca MD PhD2, Forest Sheppard, MD1

1Naval Medical Research Unit San Antonio, Joint Base San Antonio, Ft. Sam Houston, TX, 2Defense Threat Reduction Agency, Fort Belvoir, VA

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MHSRS-17-0850 Poster Session 2 - Poster #294
TXA Treatment Achieves Mild Suppression of Inflammation with Both Positive and Negative End-Organ Effects in a Rat Model of Hemorrhagic Shock
Presentation Author: Dr. Anthony Foster

Anthony D. Foster, PhD1,2, Nicholas Clark1, Philip Rothberg, MD1,2, Luke Johnston, MD1,2, Eric A. Elster, MD2, Thomas A. Davis, PhD1,2, Matthew Bradley, MD1,2



1Naval Medical Research Center, Silver Spring, MD, 2Uniformed Services University of the Health Sciences-Walter Reed National Military Medical Center, Bethesda, MD

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MHSRS-17-0945 Poster Session 2 - Poster #295
Assessment of Trainer Skill to Control Groin Wound Bleeding: Use of Junctional Tourniquet Models on a Manikin
Presentation Author: Dr. John Kragh

John F. Kragh, Jr., MD1, James K. Aden, 3d, PhD1, Stacy A. Shackelford, MD2, Virgil K. Moore, III, BBA1, Michael A. Dubick, PhD1



1U.S. Army Institute of Surgical Research, Joint Base San Antonio Fort Sam Houston, TX, 2Joint Trauma System, Defense Center of Excellence for Trauma, Joint Base San Antonio Fort Sam Houston, TX

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MHSRS-17-1012 Poster Session 2 - Poster #296
Effective Fluid Resuscitation Strategy in Protecting Early Mitochondrial Functions of Rat Brain and Liver Following Hemorrhagic Shock
Presentation Author: Dr. Pushpa Sharma

Pushpa Sharma, PhD, Brandi Benford, MS, Michael Bodo, MD, PhD1

Uniformed Services University of the Health Sciences, Bethesda MD


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MHSRS-17-1060 Poster Session 2 - Poster #297
Tissue Inflammatory Response Associated with Endothelial Dysfunction in an Anesthetized Rat Hemorrhage Model
Presentation Author: Mr. Theo Thomas

Theo Thomas, BS, Luciana Torres, PhD, Johnny Barr, MS, Ivo Torres Filho, MD, PhD, Michael Dubick, PhD

U.S. Army Institute of Surgical Research, San Antonio, TX


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MHSRS-17-1076 Poster Session 2 - Poster #298
Tissue Inflammatory Responses and Endothelial Dysfunction Associated with Upregulation of Metalloproteinases in a Rodent Model of Hemorrhage and Resuscitation
Presentation Author: Dr. Luciana Torres

Luciana Torres, PhD, Christi Salgado, BS, Michael Dubick, PhD, Ivo Torres Filho, MD, PhD


U.S. Army Institute of Surgical Research, Joint Base San Antonio, Fort Sam Houston, TX

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MHSRS-17-1080 Poster Session 2 - Poster #299
Pre-saturation of Albumin with Oleic Acid Affects Mortality and Volume Requirements in a Rat Model of Hemorrhagic Shock and Trauma with Tourniquet
Presentation Author: Dr. Alexander Penn

Alexander H. Penn, PhD, Charnae E. Williams, BS, David Barraza, MS, Michael A. Dubick, PhD, Thomas J. Walters, PhD, Ivo P. Torres Filho, MD, PhD

U.S. Army Institute of Surgical Research, Joint Base Fort Sam Houston, TX


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MHSRS-17-1091 Poster Session 2 - Poster #300
Comparison of Zone 3 Resuscitative Balloon Occlusion of the Aorta (REBOA) and the Abdominal Aortic and Junctional Tourniquet (AAJT) in a Model of Non-Compressible Pelvic Hemorrhage in Swine
Presentation Author: Dr. Jason Rall

Jason Rall, PhD1, Theodore Redman, MD2,3, Elliot Ross, MD2,3, Jonathan Morrison, PhD4, Joseph Maddry, MD1,5



159th MDW, Joint Base San Antonio,-Fort Sam Houston, TX, 2University of Texas Health Science Center at San Antonio, San Antonio TX, 3San Antonio Uniformed Services Health Education Consortium, Joint Base San Antonio, Fort Sam Houston,TX 4Queen Elizabeth University Hospital, Glasgow, UK, 5U.S.A.F. En Route Care Research Center, Joint Base San Antonio, Fort Sam Houston, TX

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