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SYLLABUS RELATING

TO

BACHELOR OF PHARMACY (B.PHARM.)


DEGREE COURSE
STRUCTURE OF THE COURSE

1. Nomenclature of the Course : Bachelor of Pharmacy

2. Abbreviation : B. Pharm.

3. Pattern : Semester

4. Number of Semesters : Eight

5. Nomenclature of the Semesters : Semester-I -VIII

6. Duration of the Semester : 15 Weeks Instructions (90 Working Days)

7. Duration of the Course : Four Years

8. Eligibility and Admission : As per AICTE and DTE norms

9. Ordinances, rules and regulations : Same as the general Ordinances, rules and

regulations of ICT UG program.

10. Examinatioons, periodic test, : Same as the general Ordinances, rules and

Class work regulations of ICT UG program.

11. Results, ATKT, award of class, : Same as the general Ordinances, rules and

, regulations of ICT UG program.

12. In-plant training : Same as the general Ordinances, rules and

regulations of ICT UG program.

13. Seminar, Project, : Same as the general Ordinances, rules and

regulations of ICT UG program.

14. Community Service Project : To be treated at par with Project in para 13

above

2

SUMMERY OF SYLLABUS



First Year B. Pharm.

SEMESTER-I

THEORY

No. Subject Head Hours/ Weeks Maximum Marks

1

2



3

4

5



6

7

Organic Chemistry-I



Mathematics-I

Pharmaceutics-I

Pharmaceutical Engineering-I

Anatomy, Physiology & Pathophysiology-I

Pharmaceutical Chemistry –I

Microbiology

2

2

2



2

2

2



2

50

50



50

50

50



50

50

Total 14 350



PRACTICALS

8

9



10

Organic Chemistry Laboratory-I

Microbiology Laboratory

Anatomy, Physiology & Pathophysiology

Laboratory

4

4



4

50

50



50

Total 12 150

Grand Total 26 500

SEMESTER-II

THEORY

No. Subject Head Hours/ Weeks Maximum Marks

1

2



3

4

5



6

7

8



Organic Chemistry-II

Mathematics- II

Pharmaceutics-II

Pharmaceutical Engineering-II

Physical Pharmacy- I

Anatomy, Physiology & Pathophysiology-II

Pharmaceutical Analysis-I

Assignments (Pharmaceutical Engineering)

2

2

2



2

2

2



2

2

50



50

50

50



50

50

50



50

Total 16 400

PRACTICALS

10

11



12

Organic Chemistry Laboratory-II

Pharmaceutics Laboratory - I

Pharmaceutical Engineering Laboratory

4

4

4



50

50

50



Total 12 150

Grand Total 28 550

3

Second Year B. Pharm



SEMESTER-III

THEORY

No. Subject Head Hours/ Weeks Maximum Marks

1

2



3

4

5



6

7

8



Organic Chemistry-III

Pharmaceutics- III

Physical Pharmacy- II

Biochemistry -I

Anatomy, Physiology & Pathophysiology-III

Psychology and Sociology

Hospital Pharmacy & Drug Store

Management

Assignments(Pharmaceutics)

2

2



2

2

2



2 ( 1+1)

2 ( 1+1)


2

50

50



50

50

50



50

50

50



Total 16 400

PRACTICALS

9

10



11

12

Pharmaceutics Laboratory - II



Physical Pharmacy Laboratory

Biochemistry Laboratory

Pharmaceutical Analysis Laboratory-I

4

4



4

4

50



50

50

50



Total 16 200

Grand Total 32 600

SEMESTER-IV

THEORY

No. Subject Head Hours/ Weeks Maximum Marks

1

2.

3



4

5

6



7

8

9



10

Organic Chemistry-IV

Pharmacology- I

Biochemistry - II

Pharmaceutical Analysis-II

Pharmaceutical & Medicinal Chemistry – II

Dispensing Pharmacy

Anatomy, Physiology & Pathophysiology-IV

Pharmaceutical Management-I

Assignments (Anatomy, Physiology &

Pathophysiology-III)

Assignments (Organic Chemistry)

2

2

2



2

2

2



2

2

2



2

50

50



50

50

50



50

50

50



50

50

Total 20 500



PRACTICALS

11

12.



Dispensing Pharmacy Laboratory

Community Service Project

4

6

50



100

Total 10 150

Grand Total 30 650

4

Third Year B. Pharm



SEMESTER-V

THEORY

No. Subject Head Hours/ Weeks Maximum Marks

1

2



3

4

5



6

7

8



9

Pharmaceutics- IV

Pharmacology- II

Biochemistry III

Pharmaceutical & Medicinal Chemistry – III

Pharmaceutical Analysis-III

Pharmaceutical Management-II

Cosmetics

Molecular Biology & Biotechnology

Assignments (Biochemistry)

2

2

2



2

2

2



2

2 (1+1)


2

50

50



50

50

50



50

50

50



50

Total 18 450

PRACTICALS

10

11



12

13

Computer Applications in Pharmacy



Pharmacology Laboratory-I

Cosmeticology Laboratory

Molecular Biology & Biotechnology

Laboratory

4

4

4



4

50

50



50

50

Total 16 200



Grand Total 34 650

SEMESTER-VI

THEORY

No. Subject Head Hours/ Weeks Maximum Marks

1

2



3

4

5



6

Pharmaceutics- V

Pharmacology- III

Pharmacognosy-I

Pharmaceutical Analysis-IV

Pharmaceutical & Medicinal Chemistry – IV

Assignments (Pharmaceutical Analysis)

2

2



2

2

2.



2

50

50



50

50

50



50

Total 12 300

PRACTICALS

7

8



9

10

11



Pharmaceutics Laboratory –III

Pharmaceutical & Medicinal Chemistry

Laboratory-I

Pharmaceutical Analysis Laboratory-II

Pharmacognosy Laboratory-I

Seminar


4

4

4



4

4

50



50

50

50



50

Total 20 250

Grand Total 32 550

5

Fourth Year B. Pharm



SEMESTER -VII

THEORY

No. Subject Head Hours/ Weeks Maximum Marks

1

2



3

4

5



6

7

8



9

Pharmaceutics – VI

Pharmacology- IV

Pharmacognosy-II

Pharmaceutical & Medicinal Chemistry – V

Pharmaceutical Analysis-V

Biopharmaceutics and Pharmacokinetics

Pharmaceutical Biotechnology

Assignments (Medicinal Chemistry)

Assignments (Biopharmaceutics)

2

2

2



2

2

2



2

2

2



50

50

50



50

50

50



50

50

50



Total 18 450

PRACTICALS

10

11



12

13

Pharmacology Lab-II



Pharmacognosy Lab-II

Pharmaceutical Analysis Lab-III

Pharmaceutics IV and Biopharmaceutics Lab.

4

4



4

4

50



50

50

50



Total 16 200

Grand Total 34 650

SEMESTER-VIII

THEORY

No. Subject Head Hours/ Weeks Maximum Marks

1

2



3

4

5



6

7

Pharmaceutics – VII



Pharmacognosy-III

Pharmaceutical & Medicinal Chemistry – VI

Clinical Pharmacy and Drug Interactions

Assignments (Pharmaceutics)

Assignments (Pharmacology)

Assignments (Pharmacognosy)

2

2

2



2

2

2



2

50

50



50

50

50



50

50

Total 14 350



PRACTICALS

8

9



10

11

Pharmaceutics Lab- V



Pharmacognosy Lab-III

Pharmaceutical & Medicinal Chemistry – II

Project

4

4



4

8

50



50

50

100



Total 20 250

Grand Total 34 600

6

First Year B.Pharm.



SEMESTER-I

Title of the Course Organic Chemistry-I

Marks 50


Number of Hours per Week 2

Total Hours 30

Class F.Y. B. Pharm

Semester I

Sr.No. Topic Hrs.

Aliphatic Compounds Including Alicyclic

Discussion of the following classes of compounds with regard to IUPAC

nomenclature, nature of bond, polarity, strengths, pKa, etc. sources, methods of

preparation, structure and physical properties(Structure property relationships), and

general reactions:

1 Hydrocarbons (alkanes, alkenes, alkynes), halogen compounds, 3

2 alcohols, ethers, thiols and thioethers, carbonyl compounds (aldehydes and ketones,

carboxylic acids, esters, anhydrides, amides), thiocarbonyl compounds,

5

3 Amines, imines, amides, nitro, Sulphoxides and sulphones, 3



4 Combination functional groups: enones, ketone-carboxylic acids, amine-carboxylic

acids, C=C - nitro, and changes in properties.

4

Aromatic Compounds



Discussion of the following classes of compounds with regard to IUPAC

nomenclature, nature of bond, polarity, strengths, pKa, etc. sources, methods of

preparation, structure and physical properties(Structure property relationships), and

general reactions:

1 Concepts of aromaticity and aromatic character, Huckel's rule, structure of and

resonance in benzene;

3

2 Hydrocarbons: monocyclic, bicyclic, tricyclic, Compounds containing one, two and



three hydroxy groups, thiols,

3

3 Ethers, Thioethers, carbonyl compounds (aldehydes and ketones, carboxylic acids,



esters, anhydrides, amides), thiocarbonyl compounds, sulfonic acids

4

4 Amines, imines, amides, nitro, Sulfoxides and sulfones 3



5 Multiple functional groups and property changes 2

Books Recommended

Sr.No. Title of the Book Author/Editor Edition/Year Publisher

1 Organic Chemistry Morrison, R. T 6th 2005 Pearson Education

2 Organic Chemistry Solomons, T.W.G 8th 2004 John Wiley & Sons,

3 Organic Chemistry Loudon G. Marc 2002 Oxford University

4 Adv.Org. Chemistry Jerry March 4th 2004 John Wiley & Sons,

7

Title of the Course Mathematics-I

Marks 50

Number of Hours per Week 2

Total Hours 30

Class F.Y. B. Pharm.

Semester I

Sr.No Topic Hrs.

1 Matrices & Determinants: Types of matrices, transpose of a matrix , inverse of a

matrix, determinant of a matrix and its properties, elementary row and column

operations on matrices, rank of a matrix, Solution of system of linear equations,

gauss elimination method eigenvalues and eigenvectors of a matrix, Cayley-

Hamilton theorem and its applications.

9

2 Differential calculus: Successive derivates, Leibitz's rule for nth derivative-



Lagrange's and Rolle’s mean value theorems, Taylor’s and Maclaurin’s series

expansions, functions of two or three variables , Partial Differentiation, Euler

formula and its applications, Local /absolute maxima and minima and its

applications to least square problems. Notion of improper integral and its

convergence. Introduction to Beta-Gamma functions, Curve Tracing

12

3 Integral Calculus: Reduction formulae; properties of integrals, determination of:



length of the curve, area of a bounded region, surface area of surface and volume

of solids, double and triple integrals, change of variables, applications to area,

volume, centre of gravity and moment of inertia etc

9

Books Recommended



Sr.No. Title Of The Book Author/Editor Edition/Year Publisher

1. Advanced Engineering

Mathematics

R. K. Jain,

S. R. K. Iyengar

3rd , 2007 Narosa

2. Calculus G. B. Thomas,

R. L. Finney

9th , 2004 Pearson Education

3. Elements Of Applied

Mathematics

P. N. Wartikar &

J. N. Wartikar

6th ,1977 Pune Vidyarthi Graha

4. Advanced Engineering

Mathematics

Erwin Kreyszig 9th , 2005 Wiley International

8

Title of the Course Pharmaceutics-I

Marks 50

Number of Hours per Week 2

Total Hours 30

Class F.Y. B. Pharm.

Semester I

Sr.No Title Hrs.

1. History of Pharmaceutics: Events leading to the formation of pharmaceutical

society of Great Britain,

2

2. Development of profession of pharmacy & pharmaceutical industry in India 2



3. Origin & Development of the pharmacopoeia – IP/BP/USP. 3

4. Introduction to dosage form & routes of administration 4

5. Dosage form design, Biopharmaceutical consideration 5

6. Introduction to GMP 4

7. Alternate system of medicine Brief introduction to Ayurvedic & Homeopathic

formulations.

2

8. GALENICALS: Introduction, size reduction, General properties of drug



constituents – solvents used in extraction of drugs, processes used for extraction

(infusion, decoction, maceration, & modifications, percolation, hot extraction &

modifications). Equipments used for large scale extractions.

Study of official extracts

8

Books Recommended



Sr.No. Title Author/Editor Edition/Year Publisher

1 Pharmaceutical

Dosage Form And

Drug Delivery

Systems

Howard C. Ansel,



Nicholas G.

Popovich, Lord V.

Alien

6th , 1995 B.I.Waverly Pvt.Ltd.,New



Delhi

2 Remington-The

Science And

Practice Of

Pharmacy

(Vol.1& 2)

David B.Troy 21st, 2006 Lippincott Williams &

Wilkins


3 Tutorial Pharmacy J.W. Cooper, Colin

Gunn


4th, 1950 Sir Isaac Pitman & Sons

Ltd.,London

4 Pharmaceutics: The

Science Of Dosage

Form Design

Michael E. Aulton 1998 Churchill-Livingstone

9

Title of the Course Pharmaceutical Engineering - I

Marks 50


Number of Hours per Week 2

Total Hours 30

Class F.Y. B. Pharm.

Semester I

Sr.No. Topic Hrs

1. Unit operations- Introduction, classification of unit operations, fundamental

principles

2

2. Fluid flow-mention of fluid properties such as viscosity, surface tension of fluid,



and hydrostatic infusing fluid flow, Bernoulli’s Theorem, flow of liquids in pipes,

laminar and turbulent flow;

3

3. Heat transfer-mention of different modes of heat transfer e.g. conduction,



convection and radiation;

2

4. Mass transfer and molecular diffusion in liquids, mass transfer in turbulent and



laminar flow, interfacial mass transfer

3

5. Refrigeration, air condition and humidification; hygrometry, humidification and



dehumidification;

2

6. Mixing : A) liquid-liquid mixing, B) Mixing small quantities of solids in liquids,



C) Mixing large quantities of solids in liquids, perfect mixing and random mixing,

degree of mixing, mechanism of mixing and demixing, rate of mixing, impellers

and propeller mixers, baffles in tanks, trough mixers, mixers, sigma and ribbon

blenders, paddle mixers, double cone blender, cube mixers, planetary mixers,

5

7. Emulsification and Homogenization: Process and equipment used and equipment



selection for, including colloid mills, Silverson type homogenizer.

5

8. Filtration and clarification- factors influencing rate of filtration, filter media and



filter aids, Nutsch filter, plate and frame filter, sparkler, leaf filters, rotary vacuum

filters, sintered glass and membrane filters-selection of filters,

4

9. Filtration of air, primary filters and HEPA filters and their evaluation; 2



10. Centrifugation- objective and requirements – hydroextractors. 2

Books Recommended

Sr.No. Title Author/Editor Edition Publisher

1 Introduction To

Chemical Engineering

Walter L. Badger,

Julius T. Banchero

International

Student Edn.

McGraw Hill Book

Company

2 Perry’s Chemical



Engineer’s Handbook

Perry Robert H.

Green Don W.

7th, 1997 McGraw Hill

3 Tutorial Pharmacy J.W. Cooper, C. Gunn 4th, 1950 Sir Isaac Pitman

4 Introduction To

Pharmaceutical Engg.

A.R. Paradkar 6th, 2004 Nirali Prakashan

10

Title of the Course Anatomy, Physiology & Pathophysiology-I

Marks 50


Number of Hours per Week 2

Total Hours 30

Class F.Y. B. Pharm.

Semester I

Sr.No Topic Hrs.

1 Structural Organization of human body, structure of human cell, cell membrane,

membrane potential, Intracellular messengers: cyclic AMP, Adenyl cyclase, protein

kinase, Phosphodiasterse, Cell injury and Inflammation

7

2 Blood and Lymphatic system



Elements of blood, properties of blood, haemopoesis, clotting of blood, significance

of

Rh, factor clotting disorders, anemia.



Anatomy- Physiology and Importance of Lymphatic system

Immunity – Cell mediated/humoral/Active/Passive

Diseases- AIDS, allergy, Myasthemis gravis, SLE, Rheumatic heart disorder

15

3 Respiratory system: Anatomy – Physiology



Exchange of gases, mechanism of respiration at lung and tissue level, Respiratory

volumes, Neural and chemical regulation of respiration, O2, CO2 carriage, hypoxia.

Diseases: COPD, Asthma, pneumonia, emphysema, pulmonary embolism, acute

respiratory failure.

8

Books Recommended: Same as under Anatomy, Physiology and Pathophysiology-IV



Title of the Course Pharmaceutical Chemistry-I

Marks 50


Number of Hours per week 2

Total Hours 30

Class F.Y. B.Pharm.

Semester I

Sr.No Topic Hrs.

1 Introduction - study of monographs of official compounds in IP; Water – detail study

of water as universal pharmaceutical vehicle.

3

2 Sources of contamination in pharmaceutical compounds (which are official in



pharmacopeias).

2

3 Limit tests prescribed – e.g. chloride, sulphate, arsenic, lead, iron, nitrate, alkali &



alkaline earth metals

3

4 Limits of – insoluble matter, soluble matter, nonvolatile matter, volatile matter,



residue on ignition & ash value.

2

11



5 Study of – major intracellular electrolytes & irons: chloride, phosphates, bicarbonate,

Na, K, Ca, Mg (including their general, physiological properties and uses such as

infusion fluids

3

6 Study of essential and trace ions: Fe, Zn, Mn, Se, S and I- official compounds and



uses

1

5 Study of Gastrointestinal Agents: antacids, protectives and adsorbants, saline



cathartics-official compounds

5

6 Study of Topical Agents: protectives, antimicrobials and astringents-official



compounds

5

7 Study of Important Inorganic Gases: oxygen, nitrogen, nitrous oxide, carbondioxide,



helium and ammonia

3

8 Study of Expectorants 1



9 Study of Inorganic Compounds: talc, barium sulphate, and other pharmaceutical aids. 2

Books Recommended

Sr.

No.


Title of the Book Author/Editor Edition Publisher

1 Inorganic, Medicinal and

Pharmaceutical Chemistry

J. H. Block,

E. B. Roche

1986 -


2 IP, BP,USP - Current -

3 Concise Inorganic Chemistry J. D. Lee, 5th , 1996 Oxford Blackwell

4 Bentley & Driver’s

Text Book of Pharmaceutical

Chemistry

L. M.


Atherden,

8th


1989

Oxford Medical

Publications.

5 Remington’s-The Science and Practice

of Pharmacy(vol.1 & 2)

David B. Troy 21st, 2006 Lippincott Williams

& Wilkins

Title of the Course

Microbiology

Marks 50


Number of Hours per Week 2

Total Hours 30

Class F.Y. B. Pharm

Semester I

Sr.No. Topic Hrs.

1 History (main focus on discovery of microscope, Louis Pasteur’s contribution,

Koch Postulates)

1

2 Application of Microbiology in the field of pharmacy

3 Different types of microscopes 1

4 Different types of staining techniques (with reference to bacteria)

�� Monochromatic staining

�� Gram staining

�� Acid fast staining

1

12

�� Capsule, flagella spore, cell wall staining



�� Negative staining

�� Motility

5 Classification of microorganisms as bacteria, yeast, mould, virus, rickettsiae, algae,

protozoa (with reference to eukaryotic and prokaryotic micro-organisms)



1

6 Bacteria: * Morphology

* Cell characteristics, habitat, nutrition

* Reproduction, cultivation

*Growth phases of bacteria, measurement of growth, factors affecting

growth


*Isolation and identification of pure cultures of bacteria with reference to

some


special biochemical testes (IMVic to diff between E. Coli and

enterobacter

*Culture media such as cultivation, storage media, enrichment media,

diferentia

media and microbiological assay media



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