The condition is first diagnosed based on detection of a systolic murmur on auscultation that can be explained by the gradual process of obstruction
Three Cardinal Symptoms of AS
Is a result of elevation of the pulmonary capillary pressure secondary to reduced compliance and/or LV dilatation
Usually develops later and reflects an imbalance between the augmented myocardial oxygen requirements and reduced oxygen availability
Caused by arrhythmias (usually ventricular tachycardia and bradycardias), hypotension, or decreased cerebral perfusion resulting from increased blood flow to exercising muscles without compensatory increase in cardiac output
Mechanical valve was associated with significantly lower 15 year mortality compared with bioprosthesis valve (66% vs. 79%) (Hammermeister, et al, 2000).
Mechanical valves are less obstructive than stented bioprosthesis valves of the same size (Bech-Hanssen, et al, 1999).
Despite a better survival rate with mechanical valve, the choice of valve should be tailored to the patient’s needs.
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