Extension 能否經由抑制 Lipase來治療青春痘? Acne vulgaris

Extension 能否經由抑制 Lipase來治療青春痘?

• Acne vulgaris

• 由Propionibacterium acnes引起

Tyrosinase inhibition?

• Tyrosinase inhibition?

• 美白?

Conea repair

• 眼角膜創傷治療

• 不溶於水，如何成為眼藥水?

• 微米化(直徑2 m)

SEM

SEM

MMP: Rabbit B

Normal Cornea

SACCHACHITIN 之劑型

References

• 1.Su, C.H., C.H. Sun, S. W. Juan, C. H. Hu, W. T. Ke, M. T. Sheu 1997

• Fungal mycelia as the source of chitin and polysaccharides and their application as skin substitutes. Biomaterials 18:1169-1174

• 2. Su CH, Sun CS, Juan SW, Ho HO, Hu CH and Sheu MT 1999

• .Development of fungal mycelia as skin substitutes: Effects on the wound healing process. NTJM.(1):31-39.

• 3. Su CH, Sun CS, Juan SW, Ho HO, Hu CH and Sheu MT 1999

• Development of fungal mycelia as skin substitutes: Effects on wound healing and fibroblast. Biomaterials.(20):61-68.

• 4. Huang WS, Fang CL, Su CH , Lai WF , Chang WC, and Tsai YW 2001

• Cytotoxicity and immunogenecity of SACCHACHITIN and its mechanism of action on skin wound healing. J. Biomedical Research.(56):93-100.

• 5. Hung WS, Lai WF, Leu B, Su CH, Fang CL, Tsai.YH 2004

• Effect of SACCHACHITIN on keratinocyte proliferation and the expressions of type I collagen and tissue-transglutaminase during skin wound healing. Journal Biomedical Material Research Part B: Applied Biomaterials.(70B):122-129.

• 6. Su CH, Liu SH, Yu SY, Hsieh YL, Ho SO, Hu CH, Sheu MT 2005.Development of fungal mycelia as a skin substitute:Characterization of keratinocyte proliferation and matrix metalloproteinase expression during improvement in the wound-healing process. Journal of Biomedical Materials Research Part A.(72A):220-227.