The 2nd International Symposium On The Calcium Sensing Receptor Omni Hotel, San Diego, usa

The 2^nd International Symposium On The Calcium Sensing Receptor

Omni Hotel, San Diego, USA
*All talk titles are tentative and subject to change.
March 3, 2015
7:00-8:00 Networking Breakfast
8:00-8:10 Introduction and Housekeeping: Dolores Shoback
8:10-8:40 Session 1: Keynote Presentation- Basic/Translational

Title: TBD

Chair: Wenhan Chang

Speaker: Gerda Breitwieser

8:40-10:15 Session 2: Molecular and Cellular Physiology of the CaSR

Co-chairs: Gerda Breitwieser and Christopher Loretz

1. 
   Jenny Yang: Structure of the CaSR
   
2. 
   Christopher Loretz: Evolution of the CaSR
   
3. 
   Geoffrey Hendy: Transcription and translation regulation of the CaSR
   
4. 
   Hans Brauner-Osborne: CaSR biased signaling
   
5. 
   Short-talk #1: Kati Leach
   

10:15-10:35 Networking_Coffee_Break'>Networking Coffee Break

10:35-11:55 Session 3: CaSR and Parathyroid Function

Co-chairs: Geoffrey Hendy and Edward Brown

1. Arthur Conigrave: CaSR and Parathyroid: Past, Present and Future

2. Donald Ward: CaSR and Parathyroid Cell Signaling

3. Maria Luisa Brandi: Recent Advances in Parathyroid Cell Secretory Models

4. Wenhan Chang: Parathyroid GABAbR1 and Ca²⁺-sensing
12:10-13:00 Working Lunch Session: Eat and Listen (Oral Poster Presentation)

Chair: Eniko Kallay

** Oral presentations will be selected from the top scoring abstracts submitted to the conference for an additional 5-minute slide presentation preceding the poster viewing.

13:00-14:00 Poster Viewing
14:00-15:40 Session 4: CaSR and Kidney Function

Co-chairs: William Goodman and Daniela Riccardi

1. Pascal Houillier – TBD (invited)

2. Jianghui Hou – CaSR, Claudin-14 and Ca²⁺ transport

3. Kakan Toka – Lesson learned from kidney-specific CaSR ablation

4. Tyler Miller – CaSR-dependent regulation of phosphorous and H⁺
15:40-16:00 Networking Coffee Break
16:00-17:00 Session 5: CaSR and Digestive Function

Co-chairs: Arthur Conigrave and Sam Cheng

1. 
   Sam Cheng:
   
2. 
   John Geibel: TBD (invited)
   
3. 
   TBD
   

17:00-18:15 Session 6: CaSR in Bone and Marrow

Co-chairs: Dolores Shoback and Dengshun Miao

1. 
   David Goltzman: CaSR and VDR in bone
   
2. 
   Romuald Mentaverri : CaSR and osteoclast funcitons
   
3. 
   Gregor Adams: CaSR in multiple myeloma and HSC's functions
   
4. 
   Short-talk # 2: Mark Rybchyn
   

18:30-20:30 Networking Dinner/Reception

March 4, 2015
7:00-8:00 Networking Breakfast
8:00-8:30 Session 7: Clinical Keynote Presentation: The calcium-sensing receptor and disorders of extracellular calcium sensing

Chair: Edward Nemeth

Speaker: Edward Brown
8:30-9:30 Session 8: CaSR Function in Breast, Skin, and inflammation

Chairs: Daniel Bikle and Dolores Shoback

1. 
   John Wysolmerski: CaSR in breast physiology and cancer
   
2. 
   Chia-Ling Tu: CaSR in skin development and wound healing
   
3. 
   Ulf Wagner: CaSR and inflammation
   

9:30-9:50 Networking Coffee Break

9:50-11:00 Session 9: CaSR Function in the Brain and Blood Vessel

Co-chairs: Wenhan Chang and Stephen Smith

1. 
   Wenhan Chang: Introduction of CaSR in brain physiology and pathology
   
2. 
   Stephen Smith: CaSR and ion channel regulation in neurons
   
3. 
   Ubaldo Armato: CaSR, astrocytes and alzheimer's
   
4. 
   Short-talk #3: Martin Schepelmann
   

11:00-12:10 Session 10: CaSR and Cancer

Co-chairs: Enikö Kallay and John Wysolmerski

1. 
   Eniko Kallay: introduction and overview of CaSR and Cancer
   
2. 
   Daniel Bikle: CaSR and VDR in skin cancer
   
3. 
   Osvaldo Rey: CaSR and colon cancer
   
4. 
   Short talk #4: TBD
   
5. 
   Short talk #5: TBD
   

12:10-1400 Lunch and Poster Viewing

12:10-13:00 Young Investigator Session: Lunch with CaSR Senior Investigators
14:00-15:40 Session 11: Treatment of Hyperparathyroidism with Calcimimetics

Co-chairs: Edward Nemeth and Masafumi Fukagawa

1. Glenn Chertow: Cinacalcet and cardiovascular outcomes (invited)

2. Masafumi Fukagawa: Cinacalcet, FGF-23/Klotho, and parathyroid hyperplasia

3. Dolores Shoback: Cinacalcet and primary HPT

4. Geoff Block: AMG 416

15:40-16:30 Session 12: Genetic Disorders of the CaSR

Co-chairs: Maria Luisa Brandi and Raj Thakker

1. 
   Rajesh Thakker: Familial hypocalciuric hypercalcemia type 1-3
   
2. 
   Michael Mannstadt: TBD (invited)
   

16:30-16:50 Networking Coffee Break

16:50-18:30 Session 13: New Implications for Calcimimetics and Calcilytics

Co-chairs: Arthur Conigrave and Edward Nemeth

1. Edward Nemeth: CaSR as therapeutic target

2. Daniela Riccardi: CaSR as a therapeutic target for asthma

3. Jason Yuan: CaSR as therapeutic target for pulmonary arterial hypertension

4. Fadil Hannan: CaSR and glucose metabolism in Nuf mice

18:30-19:30 Closing Remarks and Reception