About Incurable diseases

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  Factor V Leiden, a variant (mutated form) of human factor V (one of several substances that helps blood clot), which causes an increase in blood clotting (hypercoagulability). With this mutation, the anticoagulant protein secreted (which normally inhibits the pro-clotting activity of factor V) is not able to bind normally to Factor V, leading to a hypercoagulable state, i.e., an increased tendency for the patient to form abnormal and potentially harmful blood clots. Factor V Leiden is the most common hereditary hypercoagulability (prone to clotting) disorder amongst ethnic Europeans. It is named after the Dutch city Leiden, where it was first identified in 1994 by Prof R. Bertina et al. Suspicion of factor V Leiden being the cause for any thrombotic event should be considered in any Caucasian patient below the age of 45, or in any person with a family history of venous thrombosis.
  
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  Fatal familial insomnia – This is a prion disease that is inherited and causes insomnia and other symptoms. The average life span of a person who has Fatal Familial Insomnia is around 18 months after it developing.
  
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  Failure to thrive - Is a medical condition in which person inability to gain weight due to missing fat genes. Failure to thrive has no treatment or cured, the best way is to healthy diet. The main symptoms of FTT in child and adults is failure to gain weight, short height, irritability and mood swings.
  
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  Fetal alcohol spectrum disorder (birth defect)
  
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  Fibrodysplasia ossificans progressiva – A genetic disorder characterised by soft tissue injuries healing into bone. Despite this, the bones do not have joints and limit mobility. Cutting off the bone results in explosive bone growth. It is genetic, and no known cure exists. Furthermore, there is no approved treatment for this disease.
  
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  Fluoroquinolone toxicity syndrome – A multi-system syndrome that develops in some previously healthy patients that are prescribed an oral fluoroquinolone antibacterial drug.