DOSAGE FORMS
21
Average daily dose: 6-12 drops
For inhalation: 3-4 drops in hot water
For irritable colon: Average single dose 0.2 ml
CONTRAINDICATIONS
22
Obstruction
of bile ducts, gall bladder
inflammation, severe liver damage. In case gall
stones, to be used only after the consultant of
physician.
ADULTERATION
23
Peppermint oil can be adulterated by addition of
much cheaper cornmint oil (Mentha arvensis).
STORAGE
24
Store in well-filled, tightly-closed, light-resistant
containers in a cool place.
REFERENCES
1.
WHO monograph of selected medicinal
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https://www.webvitamins.com/Brands
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International
Pharmacopoeia.
Monograph
of
peppermint
oilLink:http://lib.njutcm.edu.cn/yaodia
n/ep/EP5.0/16_monographs/monogra
phs_l-p/Peppermint%20oil.pdf.
4.
http://www.essentialoils.co.za/essentia
l-oils/peppermint.htm.
Assessed on
25/08/08.
5.
Zsuzsanna S, Joseph M, and Judit H.
Antimicrobial and antiplasmid activities
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279–285.
6.
De Sousa AA, Soares PM, de Almeida AN,
Maia AR, de Souza EP, Assreuy
AM.Antispasmodic effect of Mentha
IJPCBS 2013, 3(3), 834-838 Anupam et al. ISSN: 2249-9504
838
piperita essential oil on tracheal smooth
muscle of rats. J Ethnopharmacol. 2010
Jul 20; 130(2):433-6.
7.
Dyer J, et al.
A study to look at the
effects of a hydrolat spray on hot
flushes in women being treated for
breast cancer. Complement. 2008.
02.003
8.
Pimentel M, Kong Y, Park S. Breath
testing to evaluate lactose intolerance in
irritable bowel syndrome correlates
with lactulose
testing and may not
reflect true lactose malabsorption.
2003; 98: 2700-4.
9.
Vernia P, Di Camillo M, Marinaro V. Dig
Liver Dis: Lactose malabsorption,
irritable bowel syndrome and self-
reported milk intolerance.2001; 33:
234-9.
10.
Tate S: Peppermint oil: A treatment for
postoperative nausea. J Adv Nurs.1997;
26: 543-549.
11.
Wang SM, Hofstadter MB, Kain ZN: An
alternative
method
to
alleviate
postoperative
nausea and vomiting in
children. J Clin Anesth. 1999;11:231-
234.
12.
Winston AW, Rinehart RS, Riley GP, et
al: Comparison of inhaled isopropyl
alcohol and intravenous ondansetron
for treatment of postoperative nausea.
AANA Journal. 2003; 71:127- 132.
13.
Sinclair DR, Chung-F, Mezei G: Can
postoperative
nausea and vomiting be
predicted?
Anesthesiology.
1999;
91:109-118.
14.
Anderson PH and Jenson NJ. Mutation
Research: Mutagenic investigation of
peppermint
oil
in
the
salmonella/mammalian salmonella test.
1984; 138: 1720.
15.
Karpauhtsis I, Pardali E, Feggou E,
Kokkini S, Scouras ZG, Mavragani-
Tsipidou P. Insecticidal and genotoxic
activities of orgeno essential oils.
Journal
of Agriculture and Food
Chemistry. 46: 1111-1115.
16.
List
of
German
Commission
E
Monographs
(Phytotherapy).
Peppermint oil (Menthae piperitae
aetheroleum) Published March 13,
1986; Revised March 13, 1990,
September 1, 1990, and July 14, 1993
available
online
link:
http://
www.heilpflanzen-
welt.de/buecher/BGA-Commission-
EMonographs/ index.htm.
17.
http://www.ehow.com/how_2295291_
use-peppermint-oilindigestion.
html.
Assessed on 24/08/08.
18.
http://www.drugs.com/enc/peppermi
nt-oil-overdose.html. As assessed on
25/08/08.
19.
Luke, E. Addiction to mentholated
cigarettes. Lancet. 1962: 110.
20.
Matthias
Behrends,
Martin
Beiderlinden, Jürgen Peters. Acute Lung
Injury After Peppermint Oil Injection.
Anesth Analg. 2005;101:1160-1162.
21.
http://content.herbalgram.org/eoprod
ucts/HerbalMedicine/
default.asp?m=76. As assessed on
26/08/08.
22.
List
of
German
Commission
E
Monographs
(Phytotherapy).
Peppermint oil (Menthae piperitae
aetheroleum) Published March 13,
1986; Revised March 13, 1990,
September 1, 1990, and July 14, 1993
available
online
link:
http://www.heilpflanzen-
welt.de/buecher/BGA
Commission-
EMonographs/index.htm
23.
Jones, L. (1998) “Establishing standards
for essential
oils and analytical
standards” Proceedings of NAHA The
World of Aromatherapy II International
Conference and Trade Show St. Louis,
Missouri.1998;146-163.
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International
Pharmacopoeia.
Monograph
of
peppermint
oil.
Link:http://lib.njutcm.
16_monographs/monographs_l-
p/Peppermint%20oil.pdf.
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