Effects of metabolic syndrome on urological diseases

Effects of metabolic syndrome on urological diseases.
Payzieva Ozoda
Fergana State University
1st year doctoral student
Turobiddinova Muntazamkhan
Fergana Institute of Public Health Medicine
Direction of treatment work 1st year student


Keywords: metabolic syndrome, urolithiasis, body mass index, hypercalciuria, hyperphosphaturia, hypomagniuria, hyperoxaluria and hyperinsulinemia, urinary stone.

The growing statistics of urological diseases in our region is a serious concern. In Uzbekistan, more than 5 thousand out of 100 thousand residents suffer from diseases of the body system organs every year. This is due not only to the environmental situation in some cities of the Republic, but also to the way of life of the population, improper nutrition and other factors that negatively affect human health. Most often, the indicator of pain with the disease is observed in the Navoi region. It is followed by Khorezm, Samarkand and Jizzakh regions. Uzbekistan today is one of the leaders in the problem of urinary bladder disease, the urolithiasis recurrence in the country is more than 45 percent.

In parallel with the increase in metabolic syndrome, the increase in urolithiasis (from 20 to 40% in the population), the prevalence of which has a pandemic scale, is of concern. Currently, sufficient evidence has been collected to show that urolithiasis is a systemic disease with different forms of interaction with metabolic syndrome. A number of authors propose to consider urolithiasis as a renal manifestation of metabolic syndrome, the frequency of its detection reaches 50% in the presence of all components of metabolic syndrome. The synergistic effect of a number of metabolic syndrome components leads not only to the appearance of urinary stones, but also to an increased risk of recurrence after surgical removal, and the pathophysiological mechanisms underlying them are extremely complex and contradictory. Independent studies provide strong evidence that increases the risk of developing urolithiasis in people with obesity and metabolic syndrome.