Effects of metabolic syndrome on urological diseases

The purpose of the study. Determination of the possible relationship of the development of urolithiasis in overweight and obese metabolically healthy patients by body mass index, urine pH and mineral composition categories of urolites.
Research results: our scientific studies have shown these results in patients with kidney-stone disease.

№	Surname, name	Age	Height	Weight	Body mass index (kg/m2) norm (18.5 - 24.99)	Ratio between weight and length	Urine Ph	Stone type
1	Zuhriddinov L	32	172	80	27.04	body weight excess	5,45	oxalate stone
2	Yaxyayev U	25	173	79	26.4	body weight excess	6,35	oxalate stone
3	Mirzayev A	20	165	83	30.49	first degree obesity	5,75	oxalate stone
4	Turiboyeva A	52	167	78	27.94	body weight excess	6,4	oxalate stone
5	Shomaxmudova M	31	165	90	33.06	first degree obesity	6,11	oxalate stone
6	Xujakeshov A	43	178	93	29.35	body weight excess	6,12	oxalate stone
7	Safarova M	62	165	69	25.34	body weight excess	6,6	cystine stone
8	Bahodirov A	33	168	78	27.64	body weight excess	6.4	oxalate stone

In our studies, we calculated the body mass index indicator using the formula discovered by Adolf Ketley.

Body mass index = body weight (kg / height m2

Body mass index	Body mass index ratio between weight and length of a person
16 and less	Significant deficiency of body weight
16—18,5	Lack of body weight
18,5—24,99	Norm
25—30	Excess body weight
30—35	first degree obesity
35—40	secondary obesity
40 and above	third degree obesity

In order to carry out the task aimed at determining the type of rock formation, a study of the mineral composition and structural properties of urinary stones was carried out using the X-ray phase analysis method (spectrometry method), which makes it possible to study the crystal structure of a small amount of substance in a mixture with other elements.
Conclusion. An increase in the body mass index is associated with a decrease in the acidity of the urine and the development of oxalate and phosphate-oxalate urolites. Prevention and treatment of obesity is a large medical and socio-economic task, the solution of which is not always successful. Various independent studies have shown that urolithiasis and obesity have common biochemical mechanisms that can reduce the risk of urinary stones. Lithogenic metabolic disorders, including increased body mass index, decreased urine volume, hypercalciuria, hyperphosphaturia, hypomagniuria, hyperoxaluria, and hyperinsulinemia, are the most important factors associated with obesity and the formation of urinary stones.