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structure, male genitalia and prostate
function, male genitalia and prostate (eg, spermatogenesis, puberty)
intercourse, orgasm, erection
Cell/tissue structure and function, including hypothalamic-pituitary-gonadal axis, sex
steroids, and gestational hormones
Reproductive system defense mechanisms and normal flora
Repair, regeneration, and changes associated with stage of life
Abnormal Processes: Health and Health Maintenance, Screening, Diagnosis,
Management, Risks, Prognosis
Infectious, immunologic, and inflammatory disorders
infectious disorders: balanitis; epididymitis; orchitis; prostatitis; sexually transmitted
infections and exposure; chancroid (Haemophilus ducreyi); genital herpes; gonorrhea
(Neisseria gonorrhoeae); human papillomavirus infection, genital/venereal/anal
warts, condylomata acuminata; lymphogranuloma venereum (Chlamydia
trachomatis); syphilis (
Treponema pallidum); trichomoniasis (
Trichomonas vaginalis);
urethritis, chlamydial and nonchlamydial, nongonococcal
immunologic and inflammatory disorders: autoimmune hypogonadism
Neoplasms: malignant neoplasms, penile, prostate, testicular, breast
Metabolic and regulatory disorders, including sexual dysfunction: erectile dysfunction,
impotence; infertility, male factor; male sexual dysfunction; premature ejaculation
Traumatic and mechanical disorders: benign prostatic hyperplasia/hypertrophy; circumcision,
including complications; epididymal cyst; hydrocele; injuries, wounds, and burns to male
genitalia, including blast injuries; penile laceration, penile fracture, Peyronie disease;
phimosis; scrotal laceration; spermatocele; testicular rupture/avulsion/laceration; torsion
of testis; urethral laceration/disruption; varicocele
Congenital disorders of the male reproductive system: hypospadias; Klinefelter syndrome;
undescended testicle
Adverse effects of drugs on the male reproductive system: alcohol; androgens, testosterone;
antipsychotics, antidepressants including selective serotonin reuptake inhibitors; beta-
adrenergic blockers; diuretic including thiazides; drug-induced priapism (eg, trazodone);
finasteride, dutasteride; sildenafil, tadalafil, vardenafil; marijuana; nitric oxide reductase
inhibitors
Endocrine System
Normal Processes
Embryonic development, fetal maturation, and perinatal changes
Organ structure and function
hypothalamus, posterior and anterior pituitary gland
thyroid gland
parathyroid gland
adrenal cortex, adrenal medulla
pancreatic islets
ovary and testis
adipose tissue
Cell/tissue/structure and function, including hormone synthesis, secretion, action,
metabolism
peptide hormones
steroid hormones, including vitamin D
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thyroid hormones
catecholamine hormones
renin-angiotensin system
Repair, regeneration, and changes associated with stage of life
Abnormal Processes: Health and Health Maintenance, Screening, Diagnosis,
Management, Risks, Prognosis
Diabetes mellitus and other disorders of the endocrine pancreas
diabetes mellitus: diabetes mellitus, type 1; diabetes mellitus, type 1.5; diabetes mellitus,
type 2; diabetes mellitus, acute complications: hyperosmolar coma, hypoglycemic shock,
ketoacidosis, including cerebral edema, associated electrolyte abnormalities; diabetes
mellitus, chronic complications: gastrointestinal/gastroparesis, neurologic/neuropathy,
ophthalmologic/retinopathy, peripheral vascular, renal/nephropathy, metabolic
syndrome
hypoglycemia and islet cell disorders: hypoglycemia (secondary to insulinoma,
surreptitious insulin use, sepsis, liver failure); hyperglycemia (secondary to
glucagonoma); hyperinsulinism; islet cell
tumors/insulinoma/somatostatinoma; pancreatic neuroendocrine tumors
Thyroid disorders: cyst, nodule; euthyroid sick syndrome; goiter (euthyroid-normal
thyroid
function with goiter); hypothyroidism; hyperthyroidism, including thyrotoxicosis and
thyroid storm; thyroiditis, including Hashimoto; Graves disease; neoplasms (benign cysts
and nodules, thyroid cancer including papillary, follicular, medullary, and anaplastic);
thyroid deficiency from pituitary disorder; infertility due to thyroid disease; secondary
hypothyroidism and hyperthyroidism
Parathyroid disorders: hyperparathyroidism; hypoparathyroidism; metabolic bone disease
Adrenal disorders: corticoadrenal insufficiency (Addison disease); adrenal
insufficiency,
secondary; hypocortisolism; Cushing syndrome; hyperaldosteronism; neoplasms,
benign and malignant (adrenal neuroblastoma, pheochromocytoma, adrenal
carcinoma, adrenal adenoma, aldosteronoma, adrenal incidentaloma); delayed and
precocious puberty; hypertensive endocrine disease
Pituitary disorders: acromegaly/gigantism; diabetes insipidus; galactorrhea not associated
with childbirth; panhypopituitarism from any cause; pituitary apoplexy (eg, Sheehan
syndrome); growth hormone deficiency; short stature; SIADH (inappropriate secretion of
ADH [vasopressin]); neoplasm, benign and malignant (pituitary adenomas,
craniopharyngioma, metastatic disease); prolactinoma and hyperprolactinemia, including
infertility due to these disorders; hypogonadism, primary and secondary
Hypothalamic endocrine disorders
Multiple endocrine neoplasia (MEN1, MEN2)
Congenital disorders: disorders of sexual differentiation; congenital adrenal hyperplasia;
androgen insensitivity/resistance syndrome; congenital hypothyroidism
Adverse effects of drugs on the endocrine system: drug, medicinal, and biologic substance
effects; exogenous steroid suppression of adrenal glands, anabolic steroids
Multisystem Processes & Disorders
Normal Processes
Principles of nutrition
generation, expenditure, and storage of energy at the whole-body level
functions of nutrients (eg, essential, trans-fatty acids, cholesterol)
Electrolyte and water metabolism
