Title of the topic: An observational study on the concept of “Aniladi dushana” in

From,

Dr Niveditha S.P

Preliminary M.S.(Ayu),

Department of Post Graduate Studies in Prasooti Tantra avam Stree Roga,

S.D.M College of Ayurveda and Hospital,

Hassan- 573201.
To,

The Registrar,

Rajiv Gandhi University of Health Sciences, Bangalore,

Karnataka.
Through:

The Principal and Head of The Department,PG studies In Prasooti Tantra avam StreeRoga,

S.D.M College of Ayurveda and Hospital,

Hassan-573201.
Subject: Submission of completed Proforma for registration of subject for

dissertation.

Respected sir,

I request you to kindly register the mentioned subject against my name for the submission of the dissertation to the Rajiv Gandhi University of Health Sciences Bangalore, Karnataka for partial fulfillment of M.D (Ayurveda).

TITLE OF THE DISSERTATION:
“A COMPARATIVE STUDY ON THE EFFECT OF LAJJALU KALKA AND PUSHYANUGA CHOORNA IN THE TREATMENT OF ASRGDARA”
Here with I am enclosing completed Proforma of synopsis for registration of subject for dissertation.
Thanking you,
Yours faithfully,

Date:

Place: Hassan (Dr Niveditha S.P)

RAJIV GHANDHI UNIVERSITY OF HEALTH SCIENCES,

BANGALORE, KARNATAKA.
ANNEXURE -II
COMPLETED PROFORMA FOR REGISTRATION OF SUBJECT

DISSERTATION.
1. NAME OF THE CANDIDATE DR NIVEDITHA S.P

AND ADDRESS : PRELIMINARY M.S (AYU)

SCHOLOR, DEPARTMENT OF

POST GRADUATES STUDIES IN

PRASOOTI TANTRA AVAM STREE ROGA,

S.D.M COLLEGE OF AYURVEDA

HASSAN.
PERMANENT ADDRESS : D/O S. PRABHAKAR,

DOOR NO. 191,

NITYANANDA NILAYA,

2^ND STAGE, 2^ND CEOSS,

VINOBHANAGAR,

SHIMOGA.

2. NAME OF THE

INSTITUTION : S.D.M COLLEGE OF

AYURVEDA AND HOSPITAL

HASSAN, KARNATAKA.

3. COURSE OF STUDY

AND SUBJECT : M.S (AYURVEDA)

PRASOOTI TANTRA AVAM STREE ROGA

4. DATE OF ADMISSION : 29/11/2010

TO COURSE
5. TITLE OF THE TOPIC : “A COMPARATIVE STUDY ON THE

EFFECT OF LAJJALU KALKA AND PUSHYANUGA CHOORNA

IN THE TREATMENT OF ASRIGDARA’’.
6. BRIEF RESUME OF THE STUDY
6.1 NEED FOR THE STUDY:

The process of cyclic menstruation is a natural phenomenon, normalcy of which gynecological health of women depends to a large extent. Regular cyclic menstruation results from the choreographed relationship between the endometrium and its regulating factors. Change in either of these frequently results in abnormal bleeding.

DUB is best defined as a abnormal bleeding from the uterus in the absence of organic pathology or genetal tract

Asrigdara characterized by excessive, prolonged, menstrual or inter-menstrual bleeding and is significantly seen in adolescent, peri-menopausal, and reproductive age group. About 10-30% of reproductive aged women suffer from this disorder

This type of artava vikara is distressing and can cause many complications like anemia and infertility . It also causes general debility, lack of concentration, discomfort etc. There is sharp increase in the incidence in modern era, hence require solution.

AYURVEDA describes wide range of treatment options in the management of Asrigdara. Among them lajjalu³ has been used since ages with other drugs in treating Asrigdara and pushyanuga churna is a reputed drug indicated in classical texts which is used in day to day practice in the management of Asrigdara .Hence lajjalu kalka as a single drug therapy in comparison with pushyanuga churna has been selected for the present study.

6.2 REVIEW OF LITERATURE

1. 
   Charaka Smhita:
   

An elaborate description of Asrigdara is available in chikitsa stana 30^th chapter.

2. 
   Susruta Samhita:
   

Here very brief description of Asrigdara with the explanation of rutukalina and anrutukalina artava vriddhi with their nidana, lakshana and chikitsa.

3. 
   Astanga Sangraha:
   

Detailed classification and its clinical features of Asrigdara is explained².
Previous research work done:

• 
  Rakta pradarrvar pushyanuga choorna cha upayoga by Dr Kulkarni H.D, from Talak Ayurved Mahavidyalaya, Puna University,Puna.
  
• 
  A study on the effect of pushyanuga choorna and Ghana-satva by Dr.Rawat Sushama, from Haridwar Rishikul State Ayurvedic College, Kanpur University, Kanpur.
  
• 
  A study on the effect of pushyanuga choorna in asrigdara by Dr.Ambilikumari .T, from Trivendrum Government Ayurvedic College, Kerela University, Thiruvananthapuram.
  
• 
  Comparative study on the effect of Kashmarya-Kutaja Ghrita Uttara-Basti and pushyanuga choorna in asrigdara by Dr.Narkhedi Deepali .V
  

6.3 OBJECTIVES OF THE STUDY:

1. 
   To evaluate the effect of lajjalu kalka in the treatment of Asrigdara.
   
2. 
   To compare the effect of lajjalu kalka and pushyanuga churna in the treatment of Asrigdara.
   

7. MATERIALS AND METHODS:
7.1 SOURCE OF DATA:

The subject for the study will be selected from the outpatient and in-patient of the department of Prasooti Tantra and Striroga department, S.D.M.College of Ayurveda and hospital, Hassan.

7.2 METHOD OF COLLECTION OF DATA:

Patients who are fulfilling the diagnostic and inclusion criteria will be selected for the study.

DIAGNOSTIC CRITERIA:

Diagnosis will be made on the basis of the symptoms like

• 
  Heavy menstrual bleeding.
  
• 
  Prolonged menstruation.
  
• 
  Inter-menstrual bleeding.
  

INCLUSION CRITERIA:

• 
  Patients between the age group of 20-50 years.
  
• 
  Patients with pratyatma lakshanas of asrigdara.
  
• 
  Patients diagnosed as DUB.
  

EXCLUSION CRITERIA:

• 
  Patients with chronic illness.
  
• 
  Patients using intrauterine contraceptive device.
  
• 
  Patients with uterine and Pelvic pathology.(fibroid, adenomyosis)
  
• 
  Benign and malignant growth.
  
• 
  Endometrial and endocervical polyp.
  
• 
  Thyroid disease.
  
• 
  Threatened , spontaneous or incomplete/ Ectopic pregnancy
  

GROUPING:

Sixty patients of Asrigdara will be randomly divided into following two groups, each comprising of 30 patients.

1. 
   Lajjalu kalka group: The patients of this group will be administered lajjalu kalka in the following dose schedule.
   

• 
  Kalka made out of leaves of lajjalu plant.
  
• 
  Dosage of amalaki gatra/size i.e,10 grams, with madhu and tandulodaka, thrice a day A/F.
  
• 
  Duration of the treatment is for 3 months
  

2. 
   Pushyanuga churna group: The patients of this group will be administered with pushyanuga churna in the following dose schedule.
   

• 
  Dosage is 4 grams, with madhu and tandulodaka, thrice a day A/F.
  
• 
  Duration of the treatment is for 3 months.
  

ASSESSMENT CRITERIA:

Assessment will be analyzed on the basis of following criteria, before and after the treatment.

1. 
   Artava pramana
   
   • 
     Number of pads used.
     

• 
  Grad 0 – spotting or 1pad/day
  
• 
  Grad 1 – 2-3 pads/day
  
• 
  Grad 2 – 4-5 pads/day
  
• 
  Grad 3 – 6-7 pads/day
  

• 
  Amount of bleeding.
  

• 
  Grad 0 – 1-2pads completely socked/cycle.
  
• 
  Grad 1 – 3-4pads completely socked/cycle.
  
• 
  Grad 2 – 5-6pads completely socked/cycle.
  
• 
  Grad 3 – more than 7 pads completely socked/cycle.
  

2. 
   Rajasrava avadhi
   

• 
  Duration of flow.
  

• 
  Grad 0 – 1-2 days/cycle
  
• 
  Grad 1 – 3-4 days/cycle
  
• 
  Grad 2 – 5-6 days/cycle
  

• 
  Grad 3 –more than 7 days/cycle
  

FOLLOW-UP STUDY:

Follow–up study of every 15 days, for 3 months

PARAMETERS OF THE STUDY:

7.3 LABORATORY INVESTIGATIONS:

• 
  Hb%
  
• 
  Blood count
  
• 
  UPT
  
• 
  USG
  
• 
  BT,CT
  
• 
  Hormonal study if required
  

7.4 HAS ETHICAL CLEARENCE BEEN OBTAINED FROM YOUR INTIUTION : YES

8. LIST OF REFERENCES :

1. Ashtanga Hrudaya of Vagbhata, uttara sthana; Dr.Kanjiv Lochan; Chaukambha Publications, New Delhi; Frist Edition 2008; PP161(shloka A.H.U.39/74,78)

2. Ashtanga Sangraha of Vagbhata, Sutra sthana; Dr.Kanjiv Lochan; Chaukambha Publications, New Delhi; Frist Edition 2008; PP32(shloka- A.S.Su.36/19)

3.Hareeta Samhita, triteeya stana,hindi transilation, by Harihara Prasad, Chukambha publication, reprinted on 2009 (shloka-Ha.S.Tr.10/80-81)

4. Sachitra Charaka Samhitha, Volume 1, Muniyal Ayurveda, Dr.U.Krishna muniyal Memorial Trust,PP119 (shloka- C.S.Ch.30/20-25)

5.Sushrutha Samhitha, sutra sthana, English Translation, P.V Sharma, Chaukambha Vishwbharathi Publication, Reprinted on 2005,PP….( shloka- Su.S.Su.14/21)

6.Sushrutha Samhitha, shareera sthana, English Translation, P.V Sharma, Chaukambha Vishwbharathi Publication, Reprinted on 2005,PP….( shloka- Su.S.Sha.2^nd chapter)

7.Williams Gynecology by johnO. Schorge…..MC Grow Hill Medical , New York, Chicago, New Delhi.

9. SIGNATURE OF THE CANDIDATE :
10.REMARKS OF THE GUIDE :
11. NAME AND DESIGNATION OF :
11.1 GUIDE : Dr Prathviraj Puranik MD(AYU),

Department of Prasooti Tantra avam

Streerora,

S.D.M.C.A and H, Hassan, Karnataka.

11.2 SIGNATURE :
11.3 CO-GUIDE :
11.4 SIGNATURE :
11.5 HEAD OF THE DEPARTMENT : Dr GAYATHRI BHAT N V MD(AYU Reader and HOD,

Department of Prasooti Tantra avam streeroga, S.D.M.C.A and H, Hassan, Karnataka.

11.6 SIGNATURE :
12.

12.1 REMARKS OF CHAIRMAN AND :

PRINCIPAL
12.2 SIGNATURE :