Computational Molecular Docking Models and Design of Diarylpentanoids for the Androgen Receptor

 9
 
Conclusion 
In conclusion, the softwares used are a valid method to test new molecules for binding affinity and 
assist in new understandings of molecular docking. The DBD was found to not be a valid drug 
target for the various curcumin analogs. Most importantly, the LBD was found to contain 2 
different binding pockets, the DHT binding pocket and the new ca27 binding pocket which is 
where the curcumin analogs preferred to bind. Finally, the AutoLigand software did not 
successfully produce a valid drug target to be further tested and compared to the current treatment 
methods.

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43 
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