The use of short-lived radionuclides has grown considerably, because larger dosages of these radionuclides can be administered to the patient with only minimal radiation dose and produce excellent image quality. The use of short-lived radionuclides has grown considerably, because larger dosages of these radionuclides can be administered to the patient with only minimal radiation dose and produce excellent image quality. A generator is constructed on the principle of the decay-growth relationship between a long-lived parent radionuclide and its short-lived daughter radionuclide
99Mo–99mTc Generator:- The 99Mo radionuclide has a half-life of 66 hr and decays by β emission. The radionuclide 99mTc has a half-life of 6 hr and decays to 99Tc by isomeric transition of 140 keV. The extreme usefulness of this generator is due to the excellent radiation characteristics of 99mTc, namely its 6-hr half-life, very little electron emission, and a high yield of 140-keV γ rays (90%), which are nearly ideal for the current generation of imaging devices in nuclear medicine
should be simple, convenient, rapid to use, and give a high yield of the daughter nuclide repeatedly and reproducibly. should be simple, convenient, rapid to use, and give a high yield of the daughter nuclide repeatedly and reproducibly. It should be properly shielded to minimize radiation exposure, and sturdy and compact for shipping. The generator eluate should be free from the parent radionuclide and the adsorbent material. Other extraneous radioactive contaminants should be absent in the eluate. must be sterile and pyrogen-free. Elution or ‘‘milking’’ of the generator is also carried out under-aseptic-conditions
- Introduction
- Production of Radioisotopes
- Some Commonly Used Radioisotopes
- Tracer Applications
- Thickness Gauging
- Radioisotope Dating
- Radioisotope Applications in Space Exploration
- Introduction
- Production of Radioisotopes
- Some Commonly Used Radionuclides
- Tracer Applications
- Thickness Gauging
- Radioisotope Dating
- Radioisotope Applications in Space Exploration
Radioisotopes with short half-lives are used in nuclear medicine because Radioisotopes with short half-lives are used in nuclear medicine because they have the same chemistry in the body as the nonradioactive atoms. in the organs of the body, they give off radiation that exposes a photographic plate (scan) giving an image of an organ.
- Introduction
- Production of Radioisotopes
- Some Commonly Used Radionuclides
- Tracer Applications
- Thickness gauging
- Radioisotope Dating
- Radioisotope Applications in Space Exploration
First 14C date: wood from tomb of Zoser (Djoser), 3rd Dynasty Egyptian king (July 12, 1948). First 14C date: wood from tomb of Zoser (Djoser), 3rd Dynasty Egyptian king (July 12, 1948). - Historic age: 4650±75 BP
- Radiocarbon age:
- 3979±350 BP
Second 14C date: wood from Hellenistic coffin - Historic age: 2300±200 BP
- Radiocarbon age: (C-?) Modern! Fake!
First “Curve of Knowns”: - 6 data points (using seven samples) spanning AD 600 to 2700 BC.
- Half life used: 5720± 47 years
Not all elements are radioactive. Those are the most useful for geologic dating are: Not all elements are radioactive. Those are the most useful for geologic dating are: U-238 Half-life = 4.5 By K-40 Half-life = 1.25 By Also, Sm-147, Rb 87, Th-232, U-235
- Introduction
- Production of Radioisotopes
- Some Commonly Used Radionuclides
- Tracer Applications
- Thickness Gauging
- Radioisotope Dating
- Radioisotope Applications in Space Exploration
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