Pathology of the urinary system

Membrano-proliferative glomerulonephritis

 → combination of the previous two types. 

 

   ∙ 

no correlation between type of injury and light microscopic appearance; 

   ∙ 

definitive diagnosis requires special techniques, e.g. fluorescent antibody test can help to 

discriminate between Ag/Ab complex deposition ("lumpy-bumpy") and anti-basement membrane 

antibody (linear); the antibody used in this test usually targets the host’s IgG fraction; 

   ∙ 

chronic stage of GN:  glomerular lesions progress to glomerulosclerosis (fibrous obliteration 

---

 

 

16

 

[scarring] of glomeruli) 

(sclerosis = hardness)

.