The 2nd International Symposium On The Calcium Sensing Receptor Omni Hotel, San Diego, usa



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The 2nd International Symposium On The Calcium Sensing Receptor

Omni Hotel, San Diego, USA
*All talk titles are tentative and subject to change.
March 3, 2015
7:00-8:00 Networking Breakfast
8:00-8:10 Introduction and Housekeeping: Dolores Shoback
8:10-8:40 Session 1: Keynote Presentation- Basic/Translational

Title: TBD

Chair: Wenhan Chang

Speaker: Gerda Breitwieser

8:40-10:15 Session 2: Molecular and Cellular Physiology of the CaSR



Co-chairs: Gerda Breitwieser and Christopher Loretz

  1. Jenny Yang: Structure of the CaSR

  2. Christopher Loretz: Evolution of the CaSR

  3. Geoffrey Hendy: Transcription and translation regulation of the CaSR

  4. Hans Brauner-Osborne: CaSR biased signaling

  5. Short-talk #1: Kati Leach

10:15-10:35 Networking_Coffee_Break'>Networking Coffee Break


10:35-11:55 Session 3: CaSR and Parathyroid Function

Co-chairs: Geoffrey Hendy and Edward Brown

1. Arthur Conigrave: CaSR and Parathyroid: Past, Present and Future

2. Donald Ward: CaSR and Parathyroid Cell Signaling

3. Maria Luisa Brandi: Recent Advances in Parathyroid Cell Secretory Models

4. Wenhan Chang: Parathyroid GABAbR1 and Ca2+-sensing
12:10-13:00 Working Lunch Session: Eat and Listen (Oral Poster Presentation)

Chair: Eniko Kallay

** Oral presentations will be selected from the top scoring abstracts submitted to the conference for an additional 5-minute slide presentation preceding the poster viewing.


13:00-14:00 Poster Viewing
14:00-15:40 Session 4: CaSR and Kidney Function

Co-chairs: William Goodman and Daniela Riccardi

1. Pascal Houillier – TBD (invited)

2. Jianghui Hou – CaSR, Claudin-14 and Ca2+ transport

3. Kakan Toka – Lesson learned from kidney-specific CaSR ablation

4. Tyler Miller – CaSR-dependent regulation of phosphorous and H+
15:40-16:00 Networking Coffee Break
16:00-17:00 Session 5: CaSR and Digestive Function

Co-chairs: Arthur Conigrave and Sam Cheng


  1. Sam Cheng:

  2. John Geibel: TBD (invited)

  3. TBD

17:00-18:15 Session 6: CaSR in Bone and Marrow



Co-chairs: Dolores Shoback and Dengshun Miao

  1. David Goltzman: CaSR and VDR in bone

  2. Romuald Mentaverri : CaSR and osteoclast funcitons

  3. Gregor Adams: CaSR in multiple myeloma and HSC's functions

  4. Short-talk # 2: Mark Rybchyn

18:30-20:30 Networking Dinner/Reception



March 4, 2015
7:00-8:00 Networking Breakfast
8:00-8:30 Session 7: Clinical Keynote Presentation: The calcium-sensing receptor and disorders of extracellular calcium sensing

Chair: Edward Nemeth

Speaker: Edward Brown
8:30-9:30 Session 8: CaSR Function in Breast, Skin, and inflammation

Chairs: Daniel Bikle and Dolores Shoback

  1. John Wysolmerski: CaSR in breast physiology and cancer

  2. Chia-Ling Tu: CaSR in skin development and wound healing

  3. Ulf Wagner: CaSR and inflammation

9:30-9:50 Networking Coffee Break


9:50-11:00 Session 9: CaSR Function in the Brain and Blood Vessel

Co-chairs: Wenhan Chang and Stephen Smith

  1. Wenhan Chang: Introduction of CaSR in brain physiology and pathology

  2. Stephen Smith: CaSR and ion channel regulation in neurons

  3. Ubaldo Armato: CaSR, astrocytes and alzheimer's

  4. Short-talk #3: Martin Schepelmann

11:00-12:10 Session 10: CaSR and Cancer



Co-chairs: Enikö Kallay and John Wysolmerski

  1. Eniko Kallay: introduction and overview of CaSR and Cancer

  2. Daniel Bikle: CaSR and VDR in skin cancer

  3. Osvaldo Rey: CaSR and colon cancer

  4. Short talk #4: TBD

  5. Short talk #5: TBD

12:10-1400 Lunch and Poster Viewing


12:10-13:00 Young Investigator Session: Lunch with CaSR Senior Investigators
14:00-15:40 Session 11: Treatment of Hyperparathyroidism with Calcimimetics

Co-chairs: Edward Nemeth and Masafumi Fukagawa

1. Glenn Chertow: Cinacalcet and cardiovascular outcomes (invited)

2. Masafumi Fukagawa: Cinacalcet, FGF-23/Klotho, and parathyroid hyperplasia

3. Dolores Shoback: Cinacalcet and primary HPT

4. Geoff Block: AMG 416

15:40-16:30 Session 12: Genetic Disorders of the CaSR



Co-chairs: Maria Luisa Brandi and Raj Thakker

  1. Rajesh Thakker: Familial hypocalciuric hypercalcemia type 1-3

  2. Michael Mannstadt: TBD (invited)

16:30-16:50 Networking Coffee Break


16:50-18:30 Session 13: New Implications for Calcimimetics and Calcilytics

Co-chairs: Arthur Conigrave and Edward Nemeth

1. Edward Nemeth: CaSR as therapeutic target

2. Daniela Riccardi: CaSR as a therapeutic target for asthma

3. Jason Yuan: CaSR as therapeutic target for pulmonary arterial hypertension



4. Fadil Hannan: CaSR and glucose metabolism in Nuf mice

18:30-19:30 Closing Remarks and Reception


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