Aa history Lovers 2010 moderators Nancy Olson and Glenn F. Chesnut page



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++++Message 6614. . . . . . . . . . . . Re: Belladonna treatment

From: corafinch . . . . . . . . . . . . 5/31/2010 6:38:00 PM


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--- In AAHistoryLovers@yahoogroups.com, Glenn Chesnut wrote:

>

> What exactly was the belladonna treatment used on Bill W. at Towns



Hospital,

when he came in for initial detoxing?


Bill Pittman, in "AA, The Way it Began," seems to have been the first to

answer


this question by reprinting the formulas from Dr. Alexander Lambert's

article in

the Journal of the American Medical Association on Sept 25, 1909, about the

"belladonna cure." The problem of course is that 25 years had elapsed by the

time Bill was treated at Town's. Lambert dissociated himself from Towns in

the


1920s, noting that patients tended to relapse quickly, and there seemed to

be

too many deaths during the detox stage.


So it isn't surprising that Silkworth described things differently in 1937

(in


the same article excerpted in the last "Moral Psychology" post). Silkworth

was


using alcohol along with sedatives in the first few days in those at risk

for


DT's. It would be a good guess that this group included Bill. He was also

using


orthocolloidal iodine and orthocolloidal gold. That sounds like something he

might have picked up from the Keeley Cure, which also included an oral

mixture

containing belladonna. I don't think Silkworth mentioned belladonna, but he



also

didn't say what sedatives he was using.


If the ingredients in the formulas seem inconsistent, keep in mind that

hyoscine


is the same as atropine, and hyoscyamine is the same as scopalamine.

Hyoscyamus,

however, is also the name of a plant, common name henbane, containing

scopalamine. Scopalamine is more sedating than atropine and although plain

belladonna tincture has both alkaloids, the predominant effect is from the

atropine. So Town's mixture would have been more sedating and less

excitatory

than pure belladonna.


A tincture is more dilute than a fluidextract, and although some reprints do

no

make this clear, Lambert called for belladonna diluted in 85% zanthoxylum,



mixed in a 2 to 1 ration with the hyoscyamus fluidextract. A confusing

detail is

Lambert's use of the term "alkaloid of hydrast" as though it were synonymous

with zanthoxylum. Hydrastis (goldenseal) is a separate plant from

Zanthoxylum

(prickly ash). However, they do have a major alkaloid, berberine, in common.


Bill Pittman quoted a reference implying that the reason for the zanthoxylum

had


to do with gastrointestinal effects. I think it may be more likely that it

was


used for its cardiovascular effects. Berberine lowers blood pressure by

reducing


peripheral resistance, and also lowers the heart rate. Both of these effects

would have been important in alcohol withdrawal, and there were few

effective

antihypertensives at the time.


I don't know why doctors thought is was helpful to make people vomit, but I

have


seen mention of it as valuable in 1930s-era article on alcohol withdrawal.

Cleaning out the GI tract from both ends was supposed to get rid of

unspecified

"toxins," and along with all the sedatives would make people so exhausted

that

they slept.


>

> Pass It On (p. 101) makes no mention of xanthoxylum (prickly ash) or

hyoscyamus (henbane) being included in the mixture.

>

> It says instead that alcoholics were given belladonna and castor oil (a



powerful laxative).

>

> Someone who remembered Towns Hospital <

where

alcoholics were "purged and puked." The purging was most probably the effect

of

the liberal does of castor oil that the patients were given, together with



belladonna. The belladonna treatment at Towns had been developed by Dr. Sam

Lambert, a reputable New York physician, but it was the chief of staff, Dr.

Silkworth, who would in time to come have the most impact on the treatment

of

alcoholism.>>


The Dr. Lambert at Town's was Alexander. His brother Samuel was also a

doctor


but with a different approach. Alexander Lambert was opposed to alcohol use

in

general and supported Prohibition. Dr. Samuel Lambert was opposed to



Prohibition

and believed that alcohol use by the non-alcoholic was health-promoting.

>

> - - - -



>

> http://health.groups.yahoo.com/group/AAHistoryLovers/message/6565

> noted that some internet references claimed that Bill W. was given a

mixture


of belladonna (deadly nightshade), xanthoxylum (prickly ash), and hyoscyamus

(henbane).

>

> But it has not been verified that Dr. Silkworth was using anything other



than

belladonna by itself.

>
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++++Message 6615. . . . . . . . . . . . Flag Ceremony San Antonio 2010

From: john wikelius . . . . . . . . . . . . 6/11/2010 8:15:00 AM


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Hope you are as ready as we are to celebrate A.A.s 75th Anniversary! This

email


is a friendly reminder about the unlimited access to an encrypted,

anonymity-protected Internet broadcast of the 2010 International Convention

Opening Flag Ceremony that will be made available through G.S.O.s A.A. Web

site


(www.aa.org
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