was to determine the presence of gait deviations and their
prevalence in a group of service members with a TTA.
METHODS
Subjects
Data from 40 AB males and 16 male individuals with a TTA
are presented in this study. The AB group included service
members between the ages of 18 and 45 years with no pain
at time of data collection and no history of lower extremity
injury requiring surgery. The TTA group included service
members between the ages of 18 and 45 years who used an
energy-storing-and-returning ankle-foot prosthesis, were able
to ambulate without an assistive device, and had been ambu-
lating for approximately 4 months. In order to detect devia-
tions not associated with acute pain, the TTA group could
not have pain of greater than 4 out of 10 anywhere on their
body at the time of data collection. The TTA group was a
convenience sample of patients within a military treatment
facility who met the inclusion criteria without bias toward
their mechanism of injury or level of physical
fitness. All
participants provided written informed consent before partic-
ipating in this institutional review board
–approved study.
Procedures
Participants underwent a biomechanical gait assessment on
level ground at a prede
fined walking speed scaled to leg
length using a Froude number
24
of 0.16. A full-body, six-
degree-of-freedom marker set comprised of 57 retrore
flective
markers was placed on 13 body segments.
25
A 26 camera
motion capture system (Motion Analysis Corp., Santa Rosa,
California) recorded marker trajectories as participants walked
across a 10-m walkway embedded with eight AMTI force
plates (AMTI, Inc., Watertown, Massachusetts) operating at
1,200 Hz. Temporal spatial, kinematic, and kinetic data were
normalized to 100% step cycle using Visual 3D (C-Motion
Inc., Rockville, Maryland). Five representative strides from
each participant were exported into MATLAB (Mathworks,
Natick, Massachusetts). Key kinematic and kinetic measures
for the ankle, knee, hip, pelvis, and trunk were de
fined as pre-
viously described.
25
Joint range of motion (ROM) was de
fined
as the difference between the maximum and minimum joint
angle values during one gait cycle. On the prosthetic side,
ankle sagittal ROM was de
fined as the difference between the
maximum and minimum joint angle values during stance.
Temporal spatial measures were determined using kinetic
gait events and foot kinematics. Step length was de
fined as
the distance between the foot centers in the anterior-posterior
direction at heel strike. Step width was calculated as the
medial-lateral distance between the heel markers on each
foot during double-limb stance. Step time was quanti
fied as
the duration between heel strike of the ipsilateral limb and
heel strike of the contralateral limb. Stance time was deter-
mined as the duration between heel strike and toe off of
the same limb. Swing time was quanti
fied as the duration
between toe off and heel strike of the same limb. Stride
length was de
fined as the distance between the foot centers
in the anterior-posterior direction on successive heel strikes
of the same limb. Stride time was quanti
fied as the duration
between successive heel strikes of the same limb.
Statistical Analysis
SPSS v.19 (SPSS Inc., Chicago, Illinois) was used for all
statistical analyses. AB and TTA group means and standard
deviations were calculated for demographic, anthropometric,
temporal spatial, kinematic, and kinetic measures. Due to
differences in sample size, and a desire to retain all avail-
able data, Mann
–Whitney non parametric tests were used
to identify differences between AB and TTA groups for
demographic-anthropometric, temporal spatial, and kinematic-
kinetic measures. The AB group
’s right lower limb was
used in comparisons made to the TTA group
’s lower limbs
(e.g., AB vs. prosthetic limb and AB vs. intact limb).
Bonferroni
–Holm corrections were performed to correct for
multiple comparisons across all measures. The Bonferroni
–
Holm method uses a step-down approach to account for
multiple comparisons by arranging
p values from the smallest
to the largest and comparing them to sequential signi
ficance
cutoffs.
26
Signi
ficance was set at a p value of 0.05. Thus,
correction factors accounting for 6, 6, and 53 comparisons
yielded minimum
p-value cutoffs of 0.0083, 0.0083, and
0.0009 for demographic-anthropometric, temporal spatial, and
kinematic-kinetic measures, respectively.
Similar to the work of O
’Sullivan,
20
the NRR for each
measure was de
fined as two standard deviations greater than
and less than the AB group mean. Microsoft Excel 2007
(Microsoft Corp., Redmond, Washington) was used to deter-
mine the upper and lower bounds of the NRR for the AB
group and the prevalence of deviations in the TTA group.
The deviation prevalence for each measure was calculated as
the percentage of participants from the TTA group with indi-
vidual mean values outside the NRR. To facilitate visualiza-
tion of the data and ease of presentation, prevalence values
were categorized into three groups; high (>50%), moderate
(25
–49%), and low (<25%).
RESULTS
Participant demographics and anthropometrics including
age, height, weight, body mass index, leg length, walking
speed, and time since independent ambulation ( TTA group
only) are listed in Table I. Only age demonstrated a signi
fi-
cant difference between groups with the TTA group being
an average of 4 years older than the AB group (
p = 0.006).
Figure 1A provides an example of a measure that demon-
strates high deviation prevalence in the TTA group with sig-
ni
ficant between group difference; 5.4% of all measures
presented here were in this category. In addition, 7.1% of
measures showed moderate deviation prevalence in the TTA
group with signi
ficant between group differences (Fig. 1B)
MILITARY MEDICINE, Vol. 181, November/December Supplement 2016
31
The Prevalence of Gait Deviations in Individuals With Transtibial Amputation