10th anniversary International Multiconference «Bioinformatics of Genome Regulation and Structure\ Systems Biology»

	2 September, Friday
	Small Hall BGRS\SB
9:00–16.30	Section “Genomics, Transcriptomics and Bioinformatics” (House of Scientists SB RAS, Small hall) Chairpersons: Ivo Grosse, Halle-Wittenberg University, Halle, Germany; Vsevolod Makeev, VIGG RAS, MIPT, Moscow, Russia
9:00–9.15	Sequencing from Roche: what the future will bring for you? Irina Karpova LCC “Roche Diagnostics Rus”, Moscow, Russia
9.15–9.30	Whole genome of the wooly mammoth: evolution through millenia Artem Nedoluzhko^1,*, A.S. Sokolov^2, F.S. Sharko^2, E.S. Boulygina^1, S.V. Tsygankova^1, A.N. Tikhonov^3, K.G. Skryabin^1,2,4, E.B. Prokhortchouk^2,4 ^1National Research Center “Kurchatov Institute”, Moscow, Russia; ^2Institute of Bioengineering, Research Center RAS, Moscow, Russia; ^3Zoological Institute, Russian Academy of Sciences, Saint Petersburg, Russia; ^4Lomonosov Moscow State University, Moscow, Russia
9.30–9.45	Opisthorchiidae triad: comparative genomics of the carcinogenic liver flukes using a draft genome of Opisthorchis felineus N. Ershov^1*, G. Fan^2,3, E. Prokhortchouk^4, V. Solovyev^5, Dmitry Afonnikov^1,6, H. Yang^2, V. Mordvinov^1, X. Liu^2, K. Skryabin^4,7 and The Opisthorchis Genome Consortium ^1ICG SB RAS, Novosibirsk, Russia; ^2BGI-Shenzhen, Shenzhen, China; ^3State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China; ^4Russian Federal Research Center for Biotechnology, Moscow, Russia; ^5Softberry Inc., Mount Kisco, NY, US; ^6NSU, Novosibirsk, Russia; ^7National Research Centre, Kurchatov Institute, Moscow, Russia
9.45–10:00	In silico mouse chromocenters content Dmitrii Ostromyshenskii, A.S. Komissarov, I.S. Kuznetsova, O.I. Podgornaya Institute of Cytology RAS, St. Petersburg, Russia
10:00–10:15	Transcriptome wide prediction of lncRNA-RNA interactions by a thermodynamics algorithm Ivan Antonov, M.A. Zamkova, A.V. Marakhonov, M.Y. Skoblov, Y.A. Medvedeva Research Center of Biotechnology RAS, Moscow, Russia
10:15–10:30	Energy metabolic dysfunction in tumor cells, molecular mechanisms and clinical significance Anna Kudryavtseva^1^,2, A.A. Dmitriev^1, O.L. Kardymon^1, A.S. Zasedatelev^1, G.S. Krasnov^1, A.V. Snezhkina^1 ^1Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. ^2Herzen Moscow Cancer Research Institute, Ministry of Health of the Russian Federation, Moscow, Russia.
10:30–11:00	GeneQuery: globally connected networks of GEO transcriptional profiles show hypothesis generation potential and reveal that tocopherols rescue TREM2-associated microglial dysfunction Aleksandr Predeus^1^,2*, T. Ulland^1, Y. Wang^1, V. Lampropoulou^1, W. Song^1, I. Arbuzov^3, F. Towfic^4, S. Gilfilan^1, E. Loginicheva^1, B.T. Edelson^1, B. Zeskind^4, M. Colonna^1, M.N. Artyomov^1 ^1Washington University School of Medicine, St. Louis, MO, USA; ^2Bioinformatics institute, Saint Petersburg, Russia; ^3ITMO University, Saint Petersburg, Russia. ^4Immuneering Corporation, Cambridge, MA, USA
11.00–11.20	Coffee break
11.20–11.50	miRNA binding sites in the mRNA of human titin gene Ilya Pinsky^1, A.T. Ivashchenko^1, S.B. Labeit^2 ^1Al-Farabi Kazakh National University, Almaty, Kazakhstan ^2Institute of Integrative Pathophysiplogy, Mannheim, Germany
11.50–12.05	Genome-wide transcriptomics as a platform for understanding the unusual resistance to muscle atrophy in hibernating dormice Guzel Gazizova^1*, O.V. Tyapkina^2, O.S. Kozlova^1, M.D. Logacheva^1,3, L.F. Nurullin^2, I.M. Vikhlyantsev^4, O.A. Gusev^1,5 ^1Kazan Federal University, Kazan, Russia; ^2Kazan Institute of Biochemistry and Biophysics KSC RAS, Kazan, Russia; ^3Lomonosov Moscow State University, Moscow, Russia; ^4Institute of Theoretical and Experimental Biophysics RAS, Puschino, Russia; ^5RIKEN, Yokohama, Japan
12.05–12.35	The first edition of mutagenesis by CRISPR/Cas in the extreme desiccation tolerant cultured cell. Takahiro Kikawada^1,2, Y. Miyata^1,3, Y. Sogame^1,4, T. Furusawa^1, S. Kikuta^5, R. Cornette^1, O. Gusev^6,7 ^1Institute of Agrobiological Sciences, NARO, Japan ^2Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Japan ^3Center for Biological Resources and Informatics, Tokyo Institute of Technology, 4. JSPS Research Fellow, 5. Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan, 6. Institute of Fundamental Medicine and Biology, Kazan Federal University , Russia, 7. Preventive Medicine & Diagnosis Innovation Program (PMI), RIKEN, Japan
12.35 -14:00	Lunch
14:00-16:00	Expert-analytical evaluation of promising research directions in bioinformatics and systems biology
16:00-16:30	Closing