Biotop-report 2013
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- Biotech Companies
72 BioTOPics 46 | September 2013 BioTOP-Report
1 Zeile bei 2 Zeilen Überschrift Biotech Companies OpTricon Entwicklungsgesellschaft für optische Technologien mbH OpTricon develops and produces mobile readers for quantitative analyzes of Immunoas- says for Point-of-Care-diagnostics, especially Lateral Flow Assays (LFA). Additional busi- ness segments are components and Systems for signal transmission and sensors for lbio- analytics. opTricon develops the devices in partnership with the customers and works as OEM-suppliers and is certified by TÜV Rheinland according EN ISO 13485:2003+AC: 2007 and EN ISO 9001:2008. optricon.de ORGANOBALANCE GmbH ORGANOBALANCE is a company specializing in microbial strain development and screen- ing. As a R&D contractor ORGANOBALANCE develops new biological products in the areas of nutrition, personal care and health care. The company draws on its own collection of mi- crobial strains suitable for food applications and its OASSYS ® bioassay systems. In the field of “metabolic engineering” ORGANOBALANCE exploits Saccharomyces cerevisiae yeast for synthesis of substances for the industrial and pharmaceutical industry. organobalance.com ORGANOBALANCE Medical AG ORGANOBALANCE Medical AG funds and promotes the research and development of nov- el therapies based on specific probiotic cultures, aiming to develop active substances and mechanisms for innovative medicinal products and medical devices, as well as offer new therapeutic concepts for hitherto inadequately treatable indications. organobalancemedical.com ovalehn GmbH Production and application of specific recipes -containing IgY for diagnostics and oral, pas- sive immune therapy. ovalehn.de Pentracor GmbH In the case of cardiac infarction, C-reactive protein (CRP) results in an increase of the pri- mary damage. Based on a new prototype, the company Pentracor GmbH aims to develop an adsorber for therapeutic reduction of CRP, lead it to approval, establish its certified production and market the product after clinical validation. pentracor.com Peptides&elephants GmbH Custom synthesis of peptides and peptide libraries Development parallel Synthesis tech- nologies Distributor of Peptide Synthesis Automation. peptides.de PharmaSol GmbH Modification of ingredients or introduction of new metabolic pathways in plants with gene-technology methods. pharmasol-berlin.de PlasmaChem GmbH PlasmaChem GmbH is an innovative R&D and manufacturing company specializing in nanomaterials, plasma- and ultra-thin film technologies. The company manufactures na- no-coated medical implants (stents), nanomaterials, additives for metal plating (applied e.g. by Siemens AG), new additives to engine oils on the base of nanodiamonds and other industrial nanoproducts. plasmachem.com PolyAn, Gesellschaft zur Herstellung von Polymeren für spezielle Anwendungen und Analytik mbH PolyAn is specialised in Molecular Surface Engineering (MSE). Using our surface modifica- tion expertise PolyAn optimises the performance of analytical systems by improving the signal-to-noise ratio as well as the reproducibility of consumables for multiplex diagnostics, LifeScience research and screening applications. PolyAn?s product portfolio includes func- tionalised microarray slides, microparticles for multiplex bead arrays and functionalised membranes for medical diagnostic applications. poly-an.de Preclinics Gesellschaft für präklinische Forschung mbH Preclinics is a commercial cooperation partner for preclinical research and development. As a competent, creative and experienced partner preclinics investigates pharmaceutical substances, therapeutic methods and proceedings as well as medical products during the preclinical phase. Additional we provide custom antibody production in llama, goat, sheep, rabbit and other species. preclinics.com Predemtec GmbH Predemtec GmbH is a company focused on the research, development and manufacture of innovative diagnostic tests for use in the detection of dementia-related risk factors. The goal has been to make the early and reliable diagnosis of various dementia-related illness- es a reality through the use of our innovative diagnostics tests. predemtecDX.com ProBioGen AG ProBioGen is a Contract Development and Manufacturing Organization (CDMO) and Tech- nology Provider, with extensive expertise in cell line engineering, process development (upstream- and downstream process) and GMP manufacturing of biopharmaceuticals. Of- fering state-of-the-art contract development and manufacturing services as well as access to proprietary cell lines (AGE1.cell lines ® ) for the manufacturing of biopharmaceuticals and vaccines. The company possesses the manufacturing authorization from the competent authority and meets the quality standards required by the EMA and the FDA guidelines. probiogen.de ProteaImmun GmbH ProteaImmun is a specialized proteomic company providing purified human proteins, an- tibodies and ELISAs. Our proteins are designed for structural and functional studies of proteases screening and evaluation of protease inhibitors and modulators. Furthermore we develop highly sensitive ELISA kits and antibodies. Our Focus: MMPs, ADAMTs, HtrAs. ProteaImmun produces a unique range of recombinant proteases for medical and pharma- ceutical research. The main focus is on human Matrix Metalloproteases (MMPs), ADAMTS and HtrA proteins which play an important role in neurodegenerative disease, ancer and arthritis. Customer Service: ProteaImmun provides activity analysis by zymography adapt- ed for MMPs. proteaimmun.net PROTEKUM - Umweltinstitut GmbH, Oranienburg We plan to eliminated fluid und solid waste products in a manner which is compatible with environment protection. Our methodology is largely based on painstaking analysis. We use modern equipment and scientific methods. Protekum offers high-quality products and services in environmental analysis redevelopment. protekum.de
73 BioTOPics 46 | September 2013 BioTOP-Report
Proteome Factory AG Biomarker & target discovery, validation, analysis of food and ingredients, absolute quan- tification of proteins and peptides, sequencing and characterization of proteins and an- tibodies (CDR), 2DE and LC-MS based proteomics studies, pharmacokinetics, pharmaco, immuno and membrane proteomics, protein identification, characterization of proteins and peptides (PTMs, e.g. phosphorylation, glycosilation), quality control, mass determina- tion, N-terminal amino acid sequencing, silver staining kit etc. proteomefactory.com Provitro GmbH Provitro combines more than ten years of experiences in commercialisation of cell culture technologies, Tissue Microarrays and immunohistochemical analyses with the scientific ex- pertise of the Pathological Institute of the Charité, Berlin. Based on a quality management system according to ISO 9001:2008, we provide our customers not only with high-quality products, CE marked in vitro-diagnostics and state-of-the-art services but also with indi- vidual solutions for their specific requests. provitro.de Rapidozym Gesellschaft für Laborhandel und DNA Diagnostika mbH Expertise of cell biologists cell manufacturing and clean room technology specialists. Fo- cuses on clinical stem cell product development portfolio are stroke, myocardial infarction and plastic surgery. rapidozym.de RENESA UG (haftungsbeschränkt) Manufacturing and distribution of rapid tests, mainly for medical purposes (Point of Care Testing). renesa.de RiNA GmbH RiNA has developed systems for cell-free protein biosynthesis based on pro- and eukary- otic cell lysates. A synthesis service is realised in RiNA’s own laboratories and complements the EasyXpress Kits (Qiagen). The purchase of Roche´s RTS-products enables RiNA now to be a key player in the field of cellfree biosynthesis with a large variety of products. Another research focus is the development of aptamers (DNA and RNA) for biosensors. rina-gmbh.eu RIPAC-LABOR GmbH RIPAC-LABOR offers high-quality diagnoses of bacterial infections, particularly in poultry, pigs and cattle, but also in other farm and domestic animals. The company uses pathogen differentiation to provide quick and effective methods for fighting pathogens. It performs resistance tests and epidemiological analyses and also focuses on producing herd-specific vaccines. ripac-labor.de RNL Europe GmbH Manufacturing of stem cells from bone marrow and adipose tissue for therapeutic and plastic-aesthetical application. Manufacturing of adult stem cells for research (mesenchy- mal stem cells, endothelial precursor cells). Banking of stem cells. rnleurope.com Roboklon GmbH Distribution, Marketing and Development of Products for Molecular Biological Research and Genetic Engineering. roboklon.de ROVALAB GmbH Our Master Mixes for QPCR, Standard-, Hot Start- and High Fidelity PCR as well as our high quality critical raw materials and reagents such as DNA Polymerases and dNTPs are designed to help you successfully and rapidly solve your scientific and manufacturing tasks. rovalab.com Royal Biotech GmbH Royal focuses on developing, manufacturing and marketing innovative kits, portable or micro-structured systems, and the next generation of diagnostic chips for near real-time environmental, food safety, disease and laboratory diagnostics. royalbiotech.com Scienion AG Scienion is a life science company in the markets of dispensing systems and microarray technologies. The product portfolio comprises hardware, consumables and services. Sci- enion’s leading product is the sciFLEXARRAYER dispensing system, available in a product line of six size versions. The dispenser allows the aspiration of ultra low liquid volumes from different reservoirs and non-contact micro drop delivery in the picoliter to microliter range onto a variety of carriers. scienion.de Sepiatec GmbH Production, development and sales of automated HPLC machines for high-throughput pu- rification and fractioning of complex substance compounds. sepiatec.com Seramun Diagnostica GmbH Seramun offers peptide synthesis, purification and conjugation of proteins, production of antibodies, customer research, in vitro-Diagnostics. We focus on the development and production of enzyme immunoassays for diagnosis of viral and bacterial infections and autoimmune diseases of the gastrointestinal tract, the development of multi-parameter assays as microtitre plate assays and as membrane immunoassays, as well as development of ready-to-use substrate solutions and for protein stabilizers. seramun.com SGS INSTITUT FRESENIUS Berlin GmbH & Co. KG Analytical laboratory services and consulting for development, production and quality con- trol of drugs. institut-fresenius.de SIFIN Institut für Immunpräparate und Nährmedien GmbH Berlin Development, production and purification of monoclonal antibodies for use in diagnostics. Development and production of blood grouping reagents, Serafol ® bedside cards and test reagents for serotyping of Salmonellae, Shigellae, E. coli and Yersiniae. Development and production of culture media for microbiological diagnosis. sifin.de Signature Diagnostics AG Signature Diagnostics is dedicated to the discovery, validation and commercial develop- ment of novel diagnostic products that predict outcome and drug response in patients with colorectal cancer (CRC), non-small cell lung cancer (NSCLC) and ovarian cancer. Signature believes that patient selection and stratification based on molecular gene signatures will soon become an important component of routine cancer treatment. signature-diagnostics.de 74 BioTOPics 46 | September 2013 BioTOP-Report
1 Zeile bei 2 Zeilen Überschrift Biotech Companies Silence Therapeutics AG Silence Therapeutics AG is a leading RNAi therapeutics development company and offers a novel, proprietary siRNA technology (AtuRNAi) and proprietary systemic delivery systems for siRNA (AtuPLEX, DACC and DBTC). SILENCE pipeline consists of both partnered and internal programs of which 3 clinical phase II and 1 clinical phase I programs are partnered with Pfizer/Quark (2 ophthalmic indications) and Novartis/Quark (2 kidney indications). Silence?s internal lead compound Atu027 is currently in a Phase I clinical study for the treatment of solid tumours. silence-therapeutics.com SINA Science Services GmbH SINA is a modern company providing elaborate services in molecular biology and protein biochemistry. Together with our industrial partners and customers from research institu- tions we develop complex cloning and mutagenesis strategies including high-throughput applications. We offer cloning of genes, expression and purification of proteins, DNA and RNA isolation from numerous biological materials and the production of competent cells with high transformation efficiency. sina-science-services.de SLM- Speziallabor für angewandte Mikrobiologie GmbH Microbiological quality control for medical devices, pharmaceuticals, cosmetics, drinking water, foodstuff, monitoring in clean rooms. speziallabor.com STRATEC Molecular GmbH STRATEC Molecular GmbH is a globally active provider of innovative system solutions for nucleic acid sample collection, stabilization, and both manual and automated purifica- tion from any sample type. Since 1992 the company is internationally respected for its outstanding and high performance technology platforms and offers a broad spectrum of superior products for molecular diagnostics, drug discovery and Life Science research. invitek.de Strix Diagnostics GmbH Strix Diagnostics is a medical diagnostics company specializing in customized develop- ment of certified analytical systems for multiparameter in vitro-diagnostics. strix-diagnostics.de Surflay Nanotec GmbH Surflay Nanotec GmbH, a spin-off company from Capsulution NanoScience AG, is special- ized on coating colloidal and planar materials with functional films. Key technology is the patented LbL-Technology ® with polymers. Applications are in the fields of separation mate- rials, pigment encapsulation, bio-sensing and diagnostic particles. In addition to customer tailored projects Surflay offers an unique range of products of tunable multifunctional nano-or microparticles and dye-labeled polymers. surflay.com t-cell Europe GmbH t-cell Europe GmbH, a spin-off of the Berlin Brandenburg Center for Regenerative Medi- cines (BCRT), is aiming to become the world’s technology leader in the application of T-cell- based therapies used in transplantation medicine. Over the next few years, with its three proprietary platform technologies, the company will develop and clinically validate novel T-cell-based products and corresponding diagnostics to regulate the immune system and treat viral infections. The company’s lead reference product will be a first-in-class Treg cell product/therapy for kidney transplantation that suppresses organ rejection in recipients t-cell.de Thanares GmbH Development, use and marketing of analytical process for diagnostic and therapeutic pur- poses. Future business activities: detection process for bioactive substances in bodily fluids, isolation, characterization and investigation of bioactive compounds from plants, in partic- ular insoluble proteins or low concentrations of proteins, development of low cost genetic systems for over-expression and/or production of such proteins. thanares.com TheraKine BioDelivery GmbH Development of antibody drug delivery systems and related tasks. therakine.com Thermo Fisher Scientific – B·R·A·H·M·S GmbH Thermo Scientific Biomarkers (B·R·A·H·M·S GmbH) explores, develops and produces new diagnostic test procedures to improve the diagnosis, and thereby the treatment, of life-threatening illnesses. This takes place with over 470 employees, in the disease areas infectiology, cardiology and pneumology as well as thyroid, autoimmunity and cardiology on the basis of our own patented biomarkers. Since October 2009 B·R·A·H·M·S GmbH is part of Thermo Fisher Scientific Inc. (NYSE: TMO), the world leader in serving science. thermoscientific.com/ brahms TIB MOLBIOL Syntheselabor GmbH In 1990, TIB MOLBIOL became the first German manufacturer of oligonucleotides. In ad- dition to designing and synthesizing primers and probes for Real-Time PCR assays, we develop and produce LightMix ® Kits for Roche Diagnostics LightCycler ® Instruments, cov- ering applications in Clinical Chemistry, Pharmacogenetics, Pathogen Detection, as well as Cancer Research. TIB MOLBIOL is ISO 13485 and ISO 9001 certified. tib-molbiol.com TissUse GmbH TissUse is a vibrant growth company providing high-value services in the area of tissue culture analysis of drug candidates, cosmetics, chemicals and consumer products. tissuse.com TransTissue Technologies GmbH TransTissue has been a subsidiary of BioTissue Technologies, Freiburg since September 2001. With more than 15 years of experience in regenerative medicine, the scientists of TransTissue Technologies have developed second-generation autologous tissue replace- ments, e.g. cartilage and bone grafts. We are mainly concerned with inventions and the development of tissue engineering products for regenerative medicine. We offer a broad panel of services in the field of regenerative medicine. transtissue.com UGA Biopharma GmbH UGA Biopharma a private Research and Development company, focuses on Research, De- velopment and Commercialization of Biopharmaceutical products under contract with other Biopharmaceutical companies. UGA Biopharma conducts power of biosciences to develop high-tech, last generation of biomedicine, diagnostic kits, molecular biology items and also offers world class services in biotechnology area. ugabiopharma.com 75 BioTOPics 46 | September 2013 BioTOP-Report
Umwelttechnik Dr. Bartetzko GmbH Feasibility studies, development, planning, construction and operation of biotechnological plants for groundwater, process water and waste water purification. Accredited microbi- ological laboratory for the investigation of drinking water, groundwater, bath water, soils, food, anti-microbial active ingredients and sterility according to Ph.Eur, approved in ac- cordance with BiostoffV and the German infection protection act (Infektionsschutzgesetz). bartetzko.com VasoTissue Technologies GmbH The company is active in the field of product development for advanced medical therapies. For its first product - the endothelialised vascular graft (“VasoGraft”)- VasoTissue obtained a manufacturing license in 2008. Currently, VasoTissue´s focus is on conducting its first clinical trial. vasotissue.de Zellwerk GmbH Zellwerk produces the proprietary Z ® RP cell cultivation system, comprising rotating bed bioreactor, GMP Breeder, Control Unit, software. Bioreactors with 50-5000 ml volume, 0,2-2 m² seeding surface, different cell carriers, can be delivered. In this culturing system cells grow tissue-like, being embedded in self-generated extra-cellular matrix. The tech- nology opens unique opportunities for the GMP-compliant expansion of stem cells and primary cells, manufacturing of cell-seeded implants as well as production of recombinant proteins. In addition, we have recently developed a new bioreactor for expansion of im- mune cells for cell therapy of leukemia and several types of cancer. zellwerk.biz Zentrum für molekulare Onkologie GmbH
Innovative methods for diagnostic and therapy of tumor diseases - Molecular genetics (K-RAS, PCA3, Septin9, ...) - Chemoresistance assay for prediction of chemotherapy - Pa- thology Development of new biomarkers and analytical services for studies. molekulare-onkologie.eu Zytomed Systems GmbH Zytomed Systems´ focus is the development, production and distribution of antibodies and detection systems for immunohistochemical cancer diagnostics as well as reagents and kits for in-situ hybridisation. zytomed-systems.de
BioTOP is a joint initiative of the state of Berlin and the state of Brandenburg under the umbrella of the Berlin Partner für Wirtschaft und Technologie GmbH and takes part in the Cluster Management HealthCapital. BioTOP is funded by the federal state of Berlin, the federal state of Brandenburg and the Investitionsbank Berlin, co-funded by the European Union (European Fund for Regional Development). Investing in your Future Yüklə 0,8 Mb. Dostları ilə paylaş:
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