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Biotech Companies
OpTricon Entwicklungsgesellschaft
für optische Technologien mbH
OpTricon develops and produces mobile readers for quantitative analyzes of Immunoas-
says for Point-of-Care-diagnostics, especially Lateral Flow Assays (LFA). Additional busi-
ness segments are components and Systems for signal transmission and sensors for lbio-
analytics. opTricon develops the devices in partnership with the customers and works as
OEM-suppliers and is certified by TÜV Rheinland according EN ISO 13485:2003+AC: 2007
and EN ISO 9001:2008.
optricon.de
ORGANOBALANCE GmbH
ORGANOBALANCE is a company specializing in microbial strain development and screen-
ing. As a R&D contractor ORGANOBALANCE develops new biological products in the areas
of nutrition, personal care and health care. The company draws on its own collection of mi-
crobial strains suitable for food applications and its OASSYS
®
bioassay systems. In the field
of “metabolic engineering” ORGANOBALANCE exploits Saccharomyces cerevisiae yeast for
synthesis of substances for the industrial and pharmaceutical industry.
organobalance.com
ORGANOBALANCE Medical AG
ORGANOBALANCE Medical AG funds and promotes the research and development of nov-
el therapies based on specific probiotic cultures, aiming to develop active substances and
mechanisms for innovative medicinal products and medical devices, as well as offer new
therapeutic concepts for hitherto inadequately treatable indications.
organobalancemedical.com
ovalehn GmbH
Production and application of specific recipes -containing IgY for diagnostics and oral, pas-
sive immune therapy.
ovalehn.de
Pentracor GmbH
In the case of cardiac infarction, C-reactive protein (CRP) results in an increase of the pri-
mary damage. Based on a new prototype, the company Pentracor GmbH aims to develop
an adsorber for therapeutic reduction of CRP, lead it to approval, establish its certified
production and market the product after clinical validation.
pentracor.com
Peptides&elephants GmbH
Custom synthesis of peptides and peptide libraries Development parallel Synthesis tech-
nologies Distributor of Peptide Synthesis Automation.
peptides.de
PharmaSol GmbH
Modification of ingredients or introduction of new metabolic pathways in plants with
gene-technology methods.
pharmasol-berlin.de
PlasmaChem GmbH
PlasmaChem GmbH is an innovative R&D and manufacturing company specializing in
nanomaterials, plasma- and ultra-thin film technologies. The company manufactures na-
no-coated medical implants (stents), nanomaterials, additives for metal plating (applied
e.g. by Siemens AG), new additives to engine oils on the base of nanodiamonds and other
industrial nanoproducts.
plasmachem.com
PolyAn, Gesellschaft zur
Herstellung von Polymeren für
spezielle Anwendungen und
Analytik mbH
PolyAn is specialised in Molecular Surface Engineering (MSE). Using our surface modifica-
tion expertise PolyAn optimises the performance of analytical systems by improving the
signal-to-noise ratio as well as the reproducibility of consumables for multiplex diagnostics,
LifeScience research and screening applications. PolyAn?s product portfolio includes func-
tionalised microarray slides, microparticles for multiplex bead arrays and functionalised
membranes for medical diagnostic applications.
poly-an.de
Preclinics Gesellschaft für
präklinische Forschung mbH
Preclinics is a commercial cooperation partner for preclinical research and development.
As a competent, creative and experienced partner preclinics investigates pharmaceutical
substances, therapeutic methods and proceedings as well as medical products during the
preclinical phase. Additional we provide custom antibody production in llama, goat, sheep,
rabbit and other species.
preclinics.com
Predemtec GmbH
Predemtec GmbH is a company focused on the research, development and manufacture of
innovative diagnostic tests for use in the detection of dementia-related risk factors. The
goal has been to make the early and reliable diagnosis of various dementia-related illness-
es a reality through the use of our innovative diagnostics tests.
predemtecDX.com
ProBioGen AG
ProBioGen is a Contract Development and Manufacturing Organization (CDMO) and Tech-
nology Provider, with extensive expertise in cell line engineering, process development
(upstream- and downstream process) and GMP manufacturing of biopharmaceuticals. Of-
fering state-of-the-art contract development and manufacturing services as well as access
to proprietary cell lines (AGE1.cell lines
®
) for the manufacturing of biopharmaceuticals and
vaccines. The company possesses the manufacturing authorization from the competent
authority and meets the quality standards required by the EMA and the FDA guidelines.
probiogen.de
ProteaImmun GmbH
ProteaImmun is a specialized proteomic company providing purified human proteins, an-
tibodies and ELISAs. Our proteins are designed for structural and functional studies of
proteases screening and evaluation of protease inhibitors and modulators. Furthermore
we develop highly sensitive ELISA kits and antibodies. Our Focus: MMPs, ADAMTs, HtrAs.
ProteaImmun produces a unique range of recombinant proteases for medical and pharma-
ceutical research. The main focus is on human Matrix Metalloproteases (MMPs), ADAMTS
and HtrA proteins which play an important role in neurodegenerative disease, ancer and
arthritis. Customer Service: ProteaImmun provides activity analysis by zymography adapt-
ed for MMPs.
proteaimmun.net
PROTEKUM - Umweltinstitut GmbH,
Oranienburg
We plan to eliminated fluid und solid waste products in a manner which is compatible with
environment protection. Our methodology is largely based on painstaking analysis. We
use modern equipment and scientific methods. Protekum offers high-quality products and
services in environmental analysis redevelopment.
protekum.de
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Biotech Companies
Proteome Factory AG
Biomarker & target discovery, validation, analysis of food and ingredients, absolute quan-
tification of proteins and peptides, sequencing and characterization of proteins and an-
tibodies (CDR), 2DE and LC-MS based proteomics studies, pharmacokinetics, pharmaco,
immuno and membrane proteomics, protein identification, characterization of proteins
and peptides (PTMs, e.g. phosphorylation, glycosilation), quality control, mass determina-
tion, N-terminal amino acid sequencing, silver staining kit etc.
proteomefactory.com
Provitro GmbH
Provitro combines more than ten years of experiences in commercialisation of cell culture
technologies, Tissue Microarrays and immunohistochemical analyses with the scientific ex-
pertise of the Pathological Institute of the Charité, Berlin. Based on a quality management
system according to ISO 9001:2008, we provide our customers not only with high-quality
products, CE marked in vitro-diagnostics and state-of-the-art services but also with indi-
vidual solutions for their specific requests.
provitro.de
Rapidozym Gesellschaft für
Laborhandel und DNA Diagnostika
mbH
Expertise of cell biologists cell manufacturing and clean room technology specialists. Fo-
cuses on clinical stem cell product development portfolio are stroke, myocardial infarction
and plastic surgery.
rapidozym.de
RENESA UG (haftungsbeschränkt)
Manufacturing and distribution of rapid tests, mainly for medical purposes (Point of Care
Testing).
renesa.de
RiNA GmbH
RiNA has developed systems for cell-free protein biosynthesis based on pro- and eukary-
otic cell lysates. A synthesis service is realised in RiNA’s own laboratories and complements
the EasyXpress Kits (Qiagen). The purchase of Roche´s RTS-products enables RiNA now to
be a key player in the field of cellfree biosynthesis with a large variety of products. Another
research focus is the development of aptamers (DNA and RNA) for biosensors.
rina-gmbh.eu
RIPAC-LABOR GmbH
RIPAC-LABOR offers high-quality diagnoses of bacterial infections, particularly in poultry,
pigs and cattle, but also in other farm and domestic animals. The company uses pathogen
differentiation to provide quick and effective methods for fighting pathogens. It performs
resistance tests and epidemiological analyses and also focuses on producing herd-specific
vaccines.
ripac-labor.de
RNL Europe GmbH
Manufacturing of stem cells from bone marrow and adipose tissue for therapeutic and
plastic-aesthetical application. Manufacturing of adult stem cells for research (mesenchy-
mal stem cells, endothelial precursor cells). Banking of stem cells.
rnleurope.com
Roboklon GmbH
Distribution, Marketing and Development of Products for Molecular Biological Research
and Genetic Engineering.
roboklon.de
ROVALAB GmbH
Our Master Mixes for QPCR, Standard-, Hot Start- and High Fidelity PCR as well as our
high quality critical raw materials and reagents such as DNA Polymerases and dNTPs are
designed to help you successfully and rapidly solve your scientific and manufacturing tasks.
rovalab.com
Royal Biotech GmbH
Royal focuses on developing, manufacturing and marketing innovative kits, portable or
micro-structured systems, and the next generation of diagnostic chips for near real-time
environmental, food safety, disease and laboratory diagnostics.
royalbiotech.com
Scienion AG
Scienion is a life science company in the markets of dispensing systems and microarray
technologies. The product portfolio comprises hardware, consumables and services. Sci-
enion’s leading product is the sciFLEXARRAYER dispensing system, available in a product
line of six size versions. The dispenser allows the aspiration of ultra low liquid volumes
from different reservoirs and non-contact micro drop delivery in the picoliter to microliter
range onto a variety of carriers.
scienion.de
Sepiatec GmbH
Production, development and sales of automated HPLC machines for high-throughput pu-
rification and fractioning of complex substance compounds.
sepiatec.com
Seramun Diagnostica GmbH
Seramun offers peptide synthesis, purification and conjugation of proteins, production of
antibodies, customer research, in vitro-Diagnostics. We focus on the development and
production of enzyme immunoassays for diagnosis of viral and bacterial infections and
autoimmune diseases of the gastrointestinal tract, the development of multi-parameter
assays as microtitre plate assays and as membrane immunoassays, as well as development
of ready-to-use substrate solutions and for protein stabilizers.
seramun.com
SGS INSTITUT FRESENIUS Berlin
GmbH & Co. KG
Analytical laboratory services and consulting for development, production and quality con-
trol of drugs.
institut-fresenius.de
SIFIN Institut für Immunpräparate
und Nährmedien GmbH Berlin
Development, production and purification of monoclonal antibodies for use in diagnostics.
Development and production of blood grouping reagents, Serafol
®
bedside cards and test
reagents for serotyping of Salmonellae, Shigellae, E. coli and Yersiniae. Development and
production of culture media for microbiological diagnosis.
sifin.de
Signature Diagnostics AG
Signature Diagnostics is dedicated to the discovery, validation and commercial develop-
ment of novel diagnostic products that predict outcome and drug response in patients with
colorectal cancer (CRC), non-small cell lung cancer (NSCLC) and ovarian cancer. Signature
believes that patient selection and stratification based on molecular gene signatures will
soon become an important component of routine cancer treatment.
signature-diagnostics.de
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Biotech Companies
Silence Therapeutics AG
Silence Therapeutics AG is a leading RNAi therapeutics development company and offers a
novel, proprietary siRNA technology (AtuRNAi) and proprietary systemic delivery systems
for siRNA (AtuPLEX, DACC and DBTC). SILENCE pipeline consists of both partnered and
internal programs of which 3 clinical phase II and 1 clinical phase I programs are partnered
with Pfizer/Quark (2 ophthalmic indications) and Novartis/Quark (2 kidney indications).
Silence?s internal lead compound Atu027 is currently in a Phase I clinical study for the
treatment of solid tumours.
silence-therapeutics.com
SINA Science Services GmbH
SINA is a modern company providing elaborate services in molecular biology and protein
biochemistry. Together with our industrial partners and customers from research institu-
tions we develop complex cloning and mutagenesis strategies including high-throughput
applications. We offer cloning of genes, expression and purification of proteins, DNA and
RNA isolation from numerous biological materials and the production of competent cells
with high transformation efficiency.
sina-science-services.de
SLM- Speziallabor für angewandte
Mikrobiologie GmbH
Microbiological quality control for medical devices, pharmaceuticals, cosmetics, drinking
water, foodstuff, monitoring in clean rooms.
speziallabor.com
STRATEC Molecular GmbH
STRATEC Molecular GmbH is a globally active provider of innovative system solutions for
nucleic acid sample collection, stabilization, and both manual and automated purifica-
tion from any sample type. Since 1992 the company is internationally respected for its
outstanding and high performance technology platforms and offers a broad spectrum of
superior products for molecular diagnostics, drug discovery and Life Science research.
invitek.de
Strix Diagnostics GmbH
Strix Diagnostics is a medical diagnostics company specializing in customized develop-
ment of certified analytical systems for multiparameter in vitro-diagnostics.
strix-diagnostics.de
Surflay Nanotec GmbH
Surflay Nanotec GmbH, a spin-off company from Capsulution NanoScience AG, is special-
ized on coating colloidal and planar materials with functional films. Key technology is the
patented LbL-Technology
®
with polymers. Applications are in the fields of separation mate-
rials, pigment encapsulation, bio-sensing and diagnostic particles. In addition to customer
tailored projects Surflay offers an unique range of products of tunable multifunctional
nano-or microparticles and dye-labeled polymers.
surflay.com
t-cell Europe GmbH
t-cell Europe GmbH, a spin-off of the Berlin Brandenburg Center for Regenerative Medi-
cines (BCRT), is aiming to become the world’s technology leader in the application of T-cell-
based therapies used in transplantation medicine. Over the next few years, with its three
proprietary platform technologies, the company will develop and clinically validate novel
T-cell-based products and corresponding diagnostics to regulate the immune system and
treat viral infections. The company’s lead reference product will be a first-in-class Treg cell
product/therapy for kidney transplantation that suppresses organ rejection in recipients
t-cell.de
Thanares GmbH
Development, use and marketing of analytical process for diagnostic and therapeutic pur-
poses. Future business activities: detection process for bioactive substances in bodily fluids,
isolation, characterization and investigation of bioactive compounds from plants, in partic-
ular insoluble proteins or low concentrations of proteins, development of low cost genetic
systems for over-expression and/or production of such proteins.
thanares.com
TheraKine BioDelivery GmbH
Development of antibody drug delivery systems and related tasks.
therakine.com
Thermo Fisher Scientific –
B·R·A·H·M·S GmbH
Thermo Scientific Biomarkers (B·R·A·H·M·S GmbH) explores, develops and produces
new diagnostic test procedures to improve the diagnosis, and thereby the treatment, of
life-threatening illnesses. This takes place with over 470 employees, in the disease areas
infectiology, cardiology and pneumology as well as thyroid, autoimmunity and cardiology
on the basis of our own patented biomarkers. Since October 2009 B·R·A·H·M·S GmbH
is part of Thermo Fisher Scientific Inc. (NYSE: TMO), the world leader in serving science.
thermoscientific.com/
brahms
TIB MOLBIOL Syntheselabor GmbH
In 1990, TIB MOLBIOL became the first German manufacturer of oligonucleotides. In ad-
dition to designing and synthesizing primers and probes for Real-Time PCR assays, we
develop and produce LightMix
®
Kits for Roche Diagnostics LightCycler
®
Instruments, cov-
ering applications in Clinical Chemistry, Pharmacogenetics, Pathogen Detection, as well as
Cancer Research. TIB MOLBIOL is ISO 13485 and ISO 9001 certified.
tib-molbiol.com
TissUse GmbH
TissUse is a vibrant growth company providing high-value services in the area of tissue
culture analysis of drug candidates, cosmetics, chemicals and consumer products.
tissuse.com
TransTissue Technologies GmbH
TransTissue has been a subsidiary of BioTissue Technologies, Freiburg since September
2001. With more than 15 years of experience in regenerative medicine, the scientists of
TransTissue Technologies have developed second-generation autologous tissue replace-
ments, e.g. cartilage and bone grafts. We are mainly concerned with inventions and the
development of tissue engineering products for regenerative medicine. We offer a broad
panel of services in the field of regenerative medicine.
transtissue.com
UGA Biopharma GmbH
UGA Biopharma a private Research and Development company, focuses on Research, De-
velopment and Commercialization of Biopharmaceutical products under contract with
other Biopharmaceutical companies. UGA Biopharma conducts power of biosciences to
develop high-tech, last generation of biomedicine, diagnostic kits, molecular biology items
and also offers world class services in biotechnology area.
ugabiopharma.com
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Biotech Companies
Umwelttechnik Dr. Bartetzko GmbH Feasibility studies, development, planning, construction and operation of biotechnological
plants for groundwater, process water and waste water purification. Accredited microbi-
ological laboratory for the investigation of drinking water, groundwater, bath water, soils,
food, anti-microbial active ingredients and sterility according to Ph.Eur, approved in ac-
cordance with BiostoffV and the German infection protection act (Infektionsschutzgesetz).
bartetzko.com
VasoTissue Technologies GmbH
The company is active in the field of product development for advanced medical therapies.
For its first product - the endothelialised vascular graft (“VasoGraft”)- VasoTissue obtained
a manufacturing license in 2008. Currently, VasoTissue´s focus is on conducting its first
clinical trial.
vasotissue.de
Zellwerk GmbH
Zellwerk produces the proprietary Z
®
RP cell cultivation system, comprising rotating bed
bioreactor, GMP Breeder, Control Unit, software. Bioreactors with 50-5000 ml volume,
0,2-2 m² seeding surface, different cell carriers, can be delivered. In this culturing system
cells grow tissue-like, being embedded in self-generated extra-cellular matrix. The tech-
nology opens unique opportunities for the GMP-compliant expansion of stem cells and
primary cells, manufacturing of cell-seeded implants as well as production of recombinant
proteins. In addition, we have recently developed a new bioreactor for expansion of im-
mune cells for cell therapy of leukemia and several types of cancer.
zellwerk.biz
Zentrum für molekulare Onkologie
GmbH
Innovative methods for diagnostic and therapy of tumor diseases - Molecular genetics
(K-RAS, PCA3, Septin9, ...) - Chemoresistance assay for prediction of chemotherapy - Pa-
thology Development of new biomarkers and analytical services for studies.
molekulare-onkologie.eu
Zytomed Systems GmbH
Zytomed Systems´ focus is the development, production and distribution of antibodies
and detection systems for immunohistochemical cancer diagnostics as well as reagents
and kits for in-situ hybridisation.
zytomed-systems.de
BioTOP is a joint initiative of the state of Berlin and the state of Brandenburg under the umbrella of the Berlin Partner für Wirtschaft und Technologie GmbH and takes part in the
Cluster Management HealthCapital. BioTOP is funded by the federal state of Berlin, the federal state of Brandenburg and the Investitionsbank Berlin, co-funded by the European
Union (European Fund for Regional Development). Investing in your Future
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