Sethoxydim Risk Assessment



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Worksheet C01b: Worker exposure estimates for boom spray (hydraulic ground spray) applications of 
sethoxydim [WkHyExp01] 
Verbal Description: The absorbed dose for the worker is calculated from the amount handled per day and the 
generic absorbed dose rate from several field studies on worker applications of a number of herbicides.  The 
amount handled per day is calculated from the application rates as well as estimates of the hours worked per day 
and acres treated per hour. 
Parameter/Assumption 
Value 
Units 
Source/Designation 
Application rates (R
Central 
0.3 
lb/acre 
APPL.TYP 
Lower 
0.09375 
APPL.LOW 
Upper 
0.375 
APPL.HI 
Hours of application per day (Hrs
Central 

hours 
USDA 1989a,b,c 
Lower 

Upper 

Acres_)_Central_16_acres/hour_USDA_1989a,b,c._Lower_11_Upper_21_Acres_treated_per_day_(_ATD_):_Hrs_×_Acres'>Acres treated per hour (Acres
Central 
16 
acres/hour 
USDA 1989a,b,c. 
Lower 
11 
Upper 
21 
Acres treated per day (ATD): Hrs × Acres 
Central 
112 
acres/day 
Lower 
66 
Upper 
168 
Amount handled per day (AHD): R × ATD 
Central 
33.6 
lb/day 
Lower 
6.1875 
Upper 
63 
Absorbed dose rate (ADR
Central 
0.0002 
(mg agent/kg bw) 
SERA 2001 
÷ (lbs agent
Lower 
0.00001 
handled per day)
Upper 
0.0009 
Absorbed dose [D
Abs
]: AHD × ADR 
Central 
6.72e-03 
mg/kg bw/day 
Lower 
6.19e-05 
Upper 
5.67e-02 
WS-19  


NOTE: T
HE 
F
OREST 
S
ERVICE WILL NOT USE AERIAL APPLICATIONS
.  T
HIS WORKSHEET IS INCLUDED AS A 
PLACE
-
HOLDER BUT THE RESULTS OF THE CALCULATIONS ARE NOT INCLUDED IN THE SUMMARY TABLES 
-
I
.
E
., 
W
ORKSHEETS 
E01
 AND 
E02. 
Worksheet C01c: Worker exposure estimates for aerial applications of sethoxydim [WKAREXP01] 
Verbal Description: The absorbed dose for the worker is calculated from the amount handled per day and the 
generic absorbed dose rate from several field studies on worker applications of a number of herbicides (SERA 
2001).  The amount handled per day is calculated from the application rates as well as estimates of the hours 
worked per day and acres treated per hour. 
Parameter/Assumption 
Value 
Units 
Source/Designation 
Application rates (R
Central 
0.3 
lb/acre 
Appl.Typ 
Lower 
0.09375 
Appl.Low 
Upper 
0.375 
Appl.Hi 
Hours of application per day (Hrs
Central 

hours 
USDA 1989a,b,c 
Lower 

Upper 

Acres treated per hour (Acres
Central 
70 
acres/hour 
USDA 1989a,b,c 
Lower 
40 
Upper 
100 
Acres treated per day (ATD): Hrs × Acres 
Central 
490 
acres/day 
Lower 
240 
Upper 
800 
Amount handled per day (AHD): R × ATD 
Central 
147 
lb/day 
Lower 
22.5 
Upper 
300 
Absorbed dose rate (ADR
Central 
0.00003 
(mg agent/kg bw) 
SERA 2001 
÷ (lbs agent
Lower 
0.000001 
handled per day)
Upper 
0.0001 
Absorbed dose [D
Abs
]: AHD × ADR 
Central 
4.41e-03 
mg/kg bw 
Lower 
2.25e-05 
Upper 
3.00e-02 
WS-20  


Worksheet C02a: Workers: Accidental Dermal Exposure Assessments Using Zero-Order Absorption Wearing 
Contaminated Gloves for One Minute [WrkDrmZr01] 
Verbal Description: Dermal absorption is calculated using the zero-order model from U.S. EPA/ORD (1992):  
Dose (mg/kg) = Kp × C × Time × S ÷ W  
Each of the above terms are described below. 
Parameter 
Value 
Units 
Source 
Body weight (W
70 
kg 
STD.BW 
Surface Area of hands (S
840 
cm

STD.Hands 
Dermal permeability (K
p

Central 
0.00027 
cm/hour 
DERM.KpC 
Lower 
0.00017 
cm/hour 
DERM.KpL 
Upper 
0.00042 
cm/hour 
DERM.KpU 
Concentration in solution (C)
 1 
Central 
3.6 
mg/mL 
APPL.TypDr 
Lower 
0.56 
mg/mL 
APPL.LowDr 
Upper 

mg/mL 
APPL.HI_Dr 
Duration of Exposure (T
0.0167 
hours 
1÷60 
Absorbed Dose (D
Abs
):  Kp × C × T × S ÷ W 
Central 
1.94e-04 
mg/kg 
Lower 
1.90e-05 
mg/kg 
Upper 
7.56e-04 
mg/kg 
1
 Note that 1 mL is equal to 1 cm
3
 and thus  mg/mL = mg/cm
3

WS-21  


Worksheet C02b: Workers: Accidental Dermal Exposure Assessments Using Zero-Order Absorption Wearing 
Contaminated Gloves for One Hour [WrkDrmZr60] 
Verbal Description: Dermal absorption is calculated using the zero-order model from U.S. EPA/ORD (1992):  
Dose (mg/kg) = Kp × C × Time × S ÷ W  
Each of the above terms are described below. 
Parameter 
Value 
Units 
Source 
Body weight (W
70 
kg 
STD.BW 
Surface Area of hands (S
840 
cm

STD.Hands 
Dermal permeability (K
p

Central 
0.00027 
cm/hour 
DERM.KpC 
Lower 
0.00017 
DERM.KpL 
Upper 
0.00042 
DERM.KpU 
Concentration in solution (C)

Central 
3.6 
mg/mL 
APPL.TypDr 
Lower 
0.56 
APPL.LowDr 
Upper 

APPL.HI_Dr 
Duration of Exposure (T

hours 
Absorbed Dose (D
Abs
):  Kp × C × T × S ÷ W 
Central 
1.17e-02 
mg/kg bw 
Lower 
1.14e-03 
Upper 
4.54e-02 
1
 Note that 1 mL is equal to 1 cm
3
 and thus  mg/mL = mg/cm
3

WS-22  


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