The Human Plutonium Injection Experiments



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The Human Plutonium Injection Experiments

208


Los Alamos Science Number 23  1995

Table 2.  The Eighteen Patients Injected With Plutonium

Case number and

Date 

Date

Survival 

Age at

Cause of

description

Injected*

of death

time

death*

death

HP-12


April 10, 1945

Apr. 13, 1953

2,925 days

63

heart failure



55-yr-old man

(8.0 yrs)

CHI-1

April 26, 1945



Oct. 3, 1945

160 days


68

cancer of chin, lungs

68-yr-old man

(5.2 months)

CAL-1

May 14, 1945



Jan. 9, 1966

7,545 days

79

heart disease



58-yr-old man

(20.7 yrs)

HP-1

Oct. 16, 1945



Jan. 12, 1960

5,201 days

81

bronchopneumonia



67-yr-old man

(14.2 yrs)

HP-2

Oct. 23, 1945



Apr. 4, 1948

894 days


50

brain disease

48-yr-old man

(2.4 yrs)

HP-3

Nov. 27, 1945



Jan. 24, 1983

13,571 days

85

acute cardiac arrest



48-yr-old woman

(37.2 yrs)

HP-4

Nov. 27, 1945



Apr. 29, 1947

518 days


20

Cushing’s syndrome

18-yr-old woman

(1.4 yrs)

HP-5

Nov. 30, 1945



Apr. 29, 1946

150 days


57

bronchopneumonia

56-yr-old man

(4.9 months)

CHI-2

Dec. 27, 1945



Jan. 13, 1946

17 days


56

breast cancer

56-yr-old woman

CHI-3 


Dec. 27, 1945

June 1946

about 170 days

not


probably

young adult male

(5.6 months)

known


Hodgin’s Disease

HP-6


Feb. 1, 1946

May 6, 1984

13,974 days

82

natural death



44-yr-old man

(38.2 yrs)

HP-7

Feb. 8, 1946



Oct. 27, 1946

261 days


60

pulmonary failure

59-yr-old woman

(8.5 months)

HP-11

Feb. 20, 1946



Feb. 26, 1946

6 days


69

bronchopneumonia

69-yr-old man

HP-8


March 9, 1946

Nov. 22, 1975

10,850 days

71

unknown



41-yr-old woman

(29.7 yrs)

HP-9

April 3, 1946



July 2, 1947

455 days


65

bronchopneumonia

64-yr-old man

(1.2 yrs)

CAL-2

April 26, 1946



Jan. 6, 1947

255 days


5

bone cancer

4-yr, 10-month-old boy

(8.4 months)

HP-10

July 16, 1946



June 2, 1957

3,974 days

63

heart disease



52-yr-old man

(10.9 yrs)

CAL-3

July 18, 1947



June 30, 1991

16,050 days

80

respiratory failure,



36-yr-old man

(44.0 yrs)

pneumonia

*The ages at injection and at death are based on the known dates of birth as determined by Pat Durbin; they differ in a few cases from the ages given by 

Langham, et. al., in LA-1151.  Some of the dates of death are based on information found by Eileen Welsome.

**The injection dose gives an upper limit for the patient’s body burden.  For example, it is now estimated that after 27 years, about 82.4 per cent of the injected 

dose would still remain in the body.



The Human Plutonium Injection Experiments

Number 23  1995  Los Alamos Science  

209

Weight of

Activity

Total

Dose to

Ailments, tissue samples,

injected

of Pu-239

effective

background

and remarks

Pu-239 (

m

g)**



(nCi)

dose (rem)



ratio

4.7


290

230


80

auto accident victim at Oak Ridge Hospital; bone

sample taken in surgery, teeth obtained later

6.5


400

19

120



cancer of chin, metastasis to lungs; near death

when injected; autospy samples taken

0.75 (239)

46 (239)


6400

858


gastric neoplasm; misdiagnosed with stomach

0.20 (238)

3,500 (238)

cancer; tumor and other tissue taken in surgery

4.6

280


380

74

duodenal ulcer, severe



gastrointestinal hemorrhage

5.1


310

80

92



hemophilia and heart disease

4.9


300

880


66

rash, hepatitis, and hypoproteinemia

4.9

300


46

90

Cushing’s syndrome, a metabolic disorder



5.1

310


14

95

Lou Gehrig’s disease;



autopsy samples taken

94.9


5,900

29

1730



breast cancer that had metastasized;

autospy samples taken

94.9

5,900


300

1790


Hodgkin’s disease

5.3


330

990


72

Addison’s disease, a hormonal deficiency disease

6.3

390


30

117


rheumatic heart disease

6.5


400

0.6


100

chronic malnutrition, alcoholism, cirrhosis of liver;

moribund at injection; autospy samples taken

6.5


400

1000


94

scleroderma, a chronic skin disease,

and duodenal ulcer

6.3


390

52

116



generalized dermititis and weakness;

autospy samples taken

2.7 

(plus radio-



169

13

52



osteogenic sarcoma, a rare form of bone cancer;

cerium & yttrium)

bone samples taken

6.1


380

410


104

acute congestive heart failure

0.006 (238)

95

155



10

purportedly bone cancer in left knee; leg

amputation removed half the plutonium; bone

samples taken; injection was intramuscular



The total effective dose was calculated using biokinetic models recommended by the International Commission on Radiological Protection, ICRP Publication 30, 

and all the values represent the dose received by each individual over the period from the time of injection to the time of death.



The dose to background ratio was calculated by taking the ratio of the patient’s total effective dose to the estimated dose for an average U.S. citizen over the 

period from the time of injection to the time of death (where the average annual U.S. effective dose equivalent was taken to be 0.360 rem).




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