Proton and Heavy Ion Therapy: An overview: January 2017
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Table 7
Adaptation of caseload estimates by the UK’s National Proton Beam Therapy Service Development
Programme to the 2012 Australian and New Zealand populations
Country
Estimated Population
in 2012 (millions)
Estimated PBT Patients
Total
Adult
Paediatric
UK
63.2
1,235
252
1,487
Australia
22.7
444
91
534
New Zealand
4.4
86
18
104
Total AUS/NZ
530
109
638
NB: all figures rounded to nearest whole number
More recently, based on evidence arising from Japanese clinical experiences, ANSTO has
estimated that 0.02 to 0.04 per cent of the Australian population would benefit from access to
particle therapy each year. This equates to approximately 4,800-9,600 patients.
As previously stated, greater certainty of domestic patient demand would require an accepted list
of particle therapy clinical indications, and subsequent modelling from current and projected
Australian and New Zealand cancer incidence and radiotherapy referral rates. This would allow for
more accurate determination of facilities required to meet both current and projected demand.
Proposed Particle Therapy Facilities in Australia
Within Australia, several jurisdictions have indicated interest in establishing PBT and carbon ion
facilities, including:
Victoria – as part of the 2015-2016 state budget, the State Government announced $2 million
funding to progress planning and development of a National Centre for Proton Beam Therapy
as part of the Victorian Comprehensive Cancer Centre (VCCC), undertaken in conjunction with
the University of Melbourne and Peter MacCallum Cancer Centre.
51
Subsequently, in August
2016, the Victorian Government announced $50 million for further planning activity, with
Parkville nominated as a potential PBT location
52
New South Wales - Westmead Hospital, in conjunction with the University of Sydney and the
University of Wollongong have developed a business case for a National Particle Therapy and
Research Centre (using carbon ions and protons) to be located at the Westmead Hospital
precinct
53
South Australia – South Australia is actively seeking to establish a proton therapy treatment
and research centre based at the South Australian Health and Biomedical Precinct
Proton and Heavy Ion Therapy: An overview: January 2017
24
Queensland (public) – the Queensland Metro North Hospital and Health Service have
developed a business plan for the potential introduction of a PBT facility at the Royal Brisbane
and Women’s Hospital. It is proposed that this facility will be developed in partnership with
the University of Queensland, the Queensland Institute of Technology, and Children’s Health
Queensland, and
Queensland (private) - in September 2014, Mater Health Services announced an alliance with
Proton Therapy Australia Pty Ltd to construct a $170 million proton beam facility,
54
and as at
October 2016 were seeking equity for land purchase near the Lady Cilento Children’s Hospital,
South Brisbane.
55
Currently, relevant entities involved in the proposed NSW, QLD and SA facilities have formalised
Memoranda of Understanding to network and integrate their planning activities. This clinician-led
collaboration has established links with ANSTO and RANZCR; and internationally with the New
Zealand government, the Queen's Medical Research Institute (UK), the European Organization for
Nuclear Research (CERN), and with particle centres in the USA, Germany, Denmark, Italy and
Japan. The collaboration is additionally seeking to undertake the development of standardised
protocols for particle therapy patient selection, treatment, physics, research, education and
training as a national collaborative effort, with professional representation through the tripartite
committee, the RANZCR, universities, and other relevant bodies, including the State public health
systems where appropriate.
Should more than one of these proposals progress to construction, there is great risk of
considerable expenditure and a potential oversupply of PBT facilities in Australia. It would be
considered preferable to have a coordinated, national approach to the introduction of particle
therapy to Australia, similar to the process recently undertaken within the UK where planning was
commenced in 2008 by the National Health Service. Following development of a strategic outline
case,
44
and hospital-led business cases, in 2013 the UK Health Secretary announced £250 million
(AU$396) funding for construction of two new PBT facilities in Manchester and London. Facility
construction commenced in 2015, with planned completion in 2018 and 2019, respectively.
If the current planning within Australia continues in the present manner, PBT is unlikely to be
introduced in a coordinated and controlled manner. The establishment of a formal bi-national
high-level reference group would provide an appropriate entity to consider and oversee the
potential introduction of this technology, with due respect to State and Territory rights. This
reference group could include appropriate representatives from the Commonwealth Government,
Australian and New Zealand jurisdictions; and relevant scientific, clinical and health consumer
entities.