Zaporozhyan state medical university departement of infectious diseases



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41 

 

ENTEROBIOSIS 



Etiology 

Enterobius vermicularis 



Epidemiology 

Anthroponosis.  

Peroral contageous helminthiasis.  

 

The mechanism of the transmission is fecal-oral 



 

 

Pathogenesis 

The infection is realized in oral cavity  

 

The maturation of the invasive eggs with larvae is 

finished in 4-6 hours on the skin of the human.  

 

Larvae in the distal section of the small intestine → 

rectum (female) → eggs on the perianal area and 

perineum 



 

The mechanic lesion of the mucous membrane → 

inflammatory changes, hemorrhages  

Clinical  

manifestations 

  

 



itch 

 



pyodermia 

 



headache  

 



disorder of sleep 

 



irritation 

 



dizziness 

Compilations 

 



appendicitis 

 



perforation with peritonitis 

 

Diagnostics 

 

perianal scrape 



                                                       Treatment 

         Etiotropic – mebendazole  

(treatment is effective only in 

observance of the rules of the personal 

hygiene) 

                       Prophylaxis 

 



dehelmintization of the patients 

 



sanitary-hygienic measures  

in the foci chemioprophylaxis is 

performed 

 

 



 


42 

TRICHOCEPHALOSIS 

Etiology 

Trichocephalus trichiuris 



Epidemiology 

Anthroponosis.  Peroral biochelminthiasis  

 

The mechanism of transmission is fecal-oral 



 

The factors of transmission are vegetables, fuits, water 



 

The infection of the human is realized in use  

with the food only matured eggs  

Pathogenesis  The eggs with invasive larvae → penetrations into the mucous 

membrane of the small intestine → the large intestine 



 

 

 

 

Traumatization of the wall of 

the large intestine → 

admixture of the bacterial flora 

→ inflammatory reaction → 

formation of the infiltrates 

(typhlitis) 

Penetration into the mucous 

and submucous layers → 

constant irritation of the 

interoreceptors → disorders of 

the function of the stomach, 

duodenum and central nervous 

system 


Clinical  

manifestations

 

 

 

 



diarrhea  

 



hemocolitis 

 



tenesmus  

 



pain in the right hypogastrium 

 



 

hypochromic anemia  

 

weakness 



 

dizziness 



 

decrease of artherial pressure 



      tachycardia  

Compilations 

 



rectal prolapse 

 



appendicitis 

 



hypochromic anemia  

Diagnostics 

 



eosinophilia 

 



hypochromic anemia  

 



finding of the eggs of helminths in feci 

Treatment 

 



albendazolum 

 



mebendazolum 

Prophylaxis 

 



detection and treatment of the patient 

 



sanitary-hygienic measures 

 



washing of vegetables and fruits 


43 

ANCYLOSTOMIDOSES (ANCYLOSTOMOSIS AND NECATOROSIS) 

 

 

Etiology 

 Ancylostoma duodenale / Necator americanus  



Epidemiology 

Anthroponosis. Percutaneous and peroral heohelminthiases 



 

Main route of transmission - percutaneous 



 

The susceptibility is general  



Pathogenesis 

Early (migratory) phase  

Late (intestinal) phase 

 

 

 

 

 



allergic reaction 

 



perivascular infiltration of the 

lungs  


Fixation of ancylostoma to 

mucous membrane of the small 

intestine (hypoalbuminemia) 

 

 

 

Clinical  

manifestations 

  

 



itch, urticar rash, increase the 

temperature, cough with asthmatic 

component (sputum with blood)   

  

 



 

nausea  



 

vomiting 



 

pain in the epigastrium 



 

diarrhea 



 

anemia is leading symptom     



    (in 3-6 month)  

 



pain in the muscles 

 



dry skin 

 



edema of the low 

extremeties  



Compilations 

 



infection of the skin in the area 

of the entrance gate → sepsis, 

tetanus, erythypilas, carbuncule 

 



Quinke’s edema, laryngospasm 

 



hypochromic anemia 

Diagnostics 

General methods 

 



leukocytosis  

 



eosinophilia 

 



increase the ESR 

 



hypochromic anemia 

 Biochemical methods 

 

decrease general protein  



 

general of serum Fe  



 

 

Specific methods: finding of the eggs of helminths in the feci  

Treatment 

Etiotropic therapy: albendazole, levamizole, 

mebendazole, thiabendazole 

 

Prophylaxis dehelmintization of the patients 

sanitary-hygienic measures devastation of 

soil 


Pathogenetic therapy: treatment of 

anemia and hypoalbuminemia, 

desensibilization 

 

 




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