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Etiology
(Diphylobotrium latum)
Epidemiology
Zoonosis. Peroral biohelminthiasis
The source of the infection and definitive host is human.
Intermediate host is a copepod (crustacean)
The ancillary host is a fresh water fish
Infection of the human is realized only in the use into the food of the
thermic insufficiency cooking fish
Pathogenesis
Mechanic influence
Attachment to the intestinal wall
→ attachment by bot to mucous
membrane → athrophy and
necrotization of the mucous
membrane
Toxicoellergic influence
Sensibilization by products of the
metabolism of helminth →
endogenic hypo- and
avitaminosis B
12
and folic acid
Clinical
manifestations
weakness
dizziness
signs of the damage of the
gastrointestinal tract
it is possible dynamic or
occlusive obstruction ileus
anemia
pallor
glossitis
loss of tonque papillae
achilia
Compilations
anemia
obstruction of the intestine (till perforation)
finding of the helminth’s eggs
in the feci
Diagnostics
hyperchromic anemia
revealation of the eggs and proglotids of D.latum
Treatment
Etiotropic therapy
Pathogenetic therapy
fenasal
Filicis maris acterium
praziquantel
vermox
treatment of anemia
Prophylaxis
treatment of the patients
the quarding of the water reservoirs
from the pollution by feci
fish tapeworm infection is prevented by throught cooking of freshwater fish
ECHINOCOCCOSIS
52
Etiology
Echinococus granulosus
Epidemiology
Zoonosis. Peroral biohelmintisis.
There are 2 types of the foci:
1. The natural foci (wild animals: beers, elks, wolfs, foxes)
2. Synantropic foci (sheeps, goats, dogs) The definitive host is
dog.
Pathogenesis Eggs of helminths → fixation on the mucous membrane of
duodenum → oncosphere → V.portae → liver (or brain, heart,
kidney) → formation of the hydatid cyst in the site of the
penetration
↓
↓
Toxico-allergic action of the
metabolic products of
Echinococcus
↓
The local damage
compression of the tissues
the disorders of trophics
necroses, granulation
replacement of the perished
by connective tissue
Clinical
manifestations
weakness, fatique
headache
increase
of the temperature
dyspeptic manifestations
skin rash, itch
Location of hydatid cysts:
Liver
(usually in the right
lobe)
jaundice (cholestasis)
pain in the right part of the chest
pain in the right subribal area
on palpation – immovable
compact formation
Lungs
dyspnea
pain in the chests
cough
Brain
clinics of the tumor
Complications The rupture of hydatid cyst → anaphylactic shock
53
The cyst may rupture:
1.
into the biliary tract → cholangitis intermittent ductal
obstruction
through the capsule of the liver → into the peritoneal cavity →
dissemination of scolices → formation of daughter cysts
Complications
an acute inflammatory reactions (peritonitis, meningitis,
pleurisy)
the suppurating of the cysts → abscess
in prolonged invasion → amyloidosis of the parenchymatous
organs
echinococcosis of the liver
There are 3 stages
mechanic jaundice
cirrosis of the liver
portal hypertension
echinococcosis of the lungs → massive hemorrhage
echinococcosis of the brain → epileptic attacks, loss of the
vision, pareses, paralyses
echinococcosis of the ovaries → rupture of the salpinx →
hemorrhage
Diagnostics
leukocytosis
anemia
accelerated ESR
eosinophylia
roentgenograms
USD
computed tomography
serological reactions (complement
fixation, hemagglutination
and other)
a skin test (Casoni)
Treatment
the leading method of the treatment is surgical
Prophylaxis
roles of the personal hygiene
helminthological investigation and dehelminthization of the
dogs
HYMENOLEPIASIS