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Standard Operating Procedure for Chemical Handling and StorageDCN1216
CNSE ConfidentialChemical Handling and Storage 0
DCN1216
CNSE Confidential
Page 4 of 43
milligrams per liter or less of mist, fume or dust, when administered by
continuous inhalation for 1 hour (or less if death occurs within 1 hour) to
albino rats weighing between 200 and 300 grams each.
3.7.4
Mixtures of these materials with ordinary materials, such as water, might
not warrant classification as highly toxic. While this system is basically
simple in application, any hazard evaluation that is required for the precise
categorization of this type of material shall be performed by experienced,
technically competent persons.
3.8
Oxidizer.
A material that readily yields oxygen or other oxidizing gas, or
that readily reacts to promote or initiate combustion of combustible
materials. Examples of other oxidizing gases include bromine, chlorine
and fluorine.
3.8.1
Class 4. An oxidizer that can undergo an explosive reaction due to
contamination or exposure to thermal or physical shock. In addition, the
oxidizer will enhance the burning rate and can cause spontaneous ignition
of combustibles.
3.8.2
Class 3. An oxidizer that will cause a severe increase in the burning rate
of combustible materials with which it comes in contact or that will undergo
vigorous self-sustained decomposition due to contamination or exposure
to heat.
3.8.3
Class 2. An oxidizer that will cause a moderate increase in the burning
rate or that causes spontaneous ignition of combustible materials with
which it comes in contact.
3.8.4
Class 1. An oxidizer whose primary hazard is that it slightly increases the
burning rate but which does not cause spontaneous ignition when it
comes in contact with combustible materials.
3.9
Toxic.
A chemical falling within any of the following categories:
3.9.1
Ingestion. A chemical that has a median lethal dose (LD
50
) of more than
50 milligrams per kilogram, but no more than 500 milligrams per kilogram
of body weight when administered orally to albino rats weighing between
200 and 300 grams each.
3.9.2
Absorption. A chemical that has a median lethal dose (LD
50
) of more than
200 milligrams per kilogram but not more than 1,000 milligrams per
kilogram of body weight when administered by continuous contact for 24
hours (or less if death occurs within 24 hours) with the bare skin of albino
rabbits weighing between 2 and 3 kilograms each.
3.9.3
Inhalation. A chemical that has a median lethal concentration (LC
50
) in
air of more than 200 parts per million but not more than 2,000 parts per
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