Der vasodilatatorische Effekt der Aminosäure l-arginin Stereospezifität und Insulinabhängigkeit
Yüklə 0,52 Mb. Pdf görüntüsü
|
- Bu səhifədəki naviqasiya:
- VI Abkürzungen
- VII Literaturverzeichnis
70 VI Abkürzungen Akt/PKB
Proteinkinase B Proteinkinase B DBP Diastolic blood pressure Diastolischer Blutdruck EDNO Endothelium derived NO Endothel-abhängiges NO EDRF
Endothelium derived relaxing factor Endothel-abhängiger relaxierender Faktor EDV End diastolic flow velocity Enddiastolische Flussgeschwindigkeit FPA Fundus pulsation rate Funduspulsationsrate GFR
Glomerulare filtration rate Glomeruläre Filtrationsrate HUVEC Human umbilical vein endothalial cells Endothelzellen menschlicher Umbilikalvenen IRS
Insulin receptor subtype Insulin-Rezeptorsubtyp L-NAME Nitro-L-arginine methyl ester Nitro-L-Argininmethylester L-NMMA N G -monomethyl-L-arginine N G -monomethyl-L-arginin MAP Mean arterial pressure Mittlerer arterieller Druck MFV
Mean flow velocity Mittlere Flussgeschwindigkeit NO Nitric oxide Stickstoffmonoxid, Stickoxid, Stickstoff-(II)-oxid NOS Nitric oxide synthethase Stickstoffmonoxid-Synthetase PFV
Peak flow velocity Spitzenflussgeschwindigkeit PACAP Pituirary adenylat cyclase-activating polypeptid Hypophysäres Adenylatzyklase- aktivierendes Polypeptid PHI
Peptide histidine isoleucine Peptidisches Histidin-Isoleucin PI3K Phosphatidyl 3-kinase Phosphatidyl-3-kinase PR Pulse rate Pulsfrequenz PSV Peak systolic flow velocity Systolische Spitzen- flussgeschwindigkeit RI Resistance index
Widerstandsindex 71 RPF
Renal plasma flow Renaler Plasmafluss RVR Renal vascular resistance Renaler Gefäßwiderstand SBP Systolic blood pressre Systolischer Blutdruck VSMC Vascular smooth muscle cell Glatte Gefäßmuskelzellen PACAP
pituitary adenylat cyclase-activating polypeptid hypophysäres Adenylatzyklase- aktivierendes Polypeptid PHI Peptide histidine isoleucine Peptidisches Histidin-Isoleucin
72 VII Literaturverzeichnis
Akesson,B., Mosen,H., Panagiotidis,G. & Lundquist,I. Interaction of the islet nitric oxide system with L-arginine-induced secretion of insulin and glucagon in mice. Br. J. Pharmacol. 119, 758-764 (1996). Alm A. Adler's Physiology of the eye: Clinical application St. Louis Mosby year book. Ocular Circulation 9 th , 198-227 (1992). Alm,A. & Bill,A. Ocular and optic nerve blood flow at normal and increased intraocular pressures in monkeys (Macaca irus): a study with radioactively labelled microspheres including flow determinations in brain and some other tissues. Exp. Eye Res. 15, 15-29 (1973).
American National Standarts Institute. Safe use of lasers. (1986). Amezcua,J.L., Palmer,R.M., de Souza,B.M. & Moncada,S. Nitric oxide synthesized from L-arginine regulates vascular tone in the coronary circulation of the rabbit. Br. J.
Bacchus,R.A. & London,D.R. The measurement of arginine in plasma. Clin. Chim. Acta 33, 479-482 (1971). Baron,A.D. & Brechtel,G. Insulin differentially regulates systemic and skeletal muscle vascular resistance. Am. J. Physiol 265, E61-E67 (1993). Baron,A.D., Brechtel,G., Wallace,P. & Edelman,S.V. Rates and tissue sites of non- insulin- and insulin-mediated glucose uptake in humans. Am. J. Physiol 255, E769- E774 (1988). Baron,A.D. Hemodynamic actions of insulin. Am. J. Physiol 267, E187-E202 (1994).
73 Baron,A.D., Brechtel-Hook,G., Johnson,A. & Hardin,D. Skeletal muscle blood flow. A possible link between insulin resistance and blood pressure. Hypertension 21. 129-135 (1993).
Baron,A.D. Insulin resistance and vascular function. J. Diabetes Complications 16, 92- 102 (2002). Baron,A.D. Vascular reactivity. Am. J. Cardiol. 84, 25J-27J (1999). Baudouin,S.V., Bath,P., Martin,J.F., Du,B.R. & Evans,T.W. L-arginine infusion has no effect on systemic haemodynamics in normal volunteers, or systemic and pulmonary haemodynamics in patients with elevated pulmonary vascular resistance. Br. J. Clin. Pharmacol. 36 , 45-49 (1993). Baylis,C., Harton,P. & Engels,K. Endothelial derived relaxing factor controls renal hemodynamics in the normal rat kidney. J. Am. Soc. Nephrol. 1. 875-881 (1990). Bode-Boger,S.M. et al., L-arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects. Clin. Sci. (Lond) 87, 303-310 (1994). Bogle,R.G., Coade,S.B., Moncada,S., Pearson,J.D. & Mann,G.E. Bradykinin and ATP stimulate L-arginine uptake and nitric oxide release in vascular endothelial cells.
Bommel,H.M. et al., Anti-pterins as tools to characterize the function of tetrahydrobiopterin in NO synthase. J. Biol. Chem. 273, 33142-33149 (1998). Bredt,D.S. et al., Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase. Nature 351. 714-718 (1991). Butler,J.M. et al., Effects of VIIth (facial) nerve degeneration on vasoactive intestinal polypeptide and substance P levels in ocular and orbital tissues of the rabbit. Exp. Eye
Yüklə 0,52 Mb. Dostları ilə paylaş:
|